能谱CT血管钙化参数与腹主动脉钙化指数的相关性研究
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摘要
目的探讨能谱CT血管钙化参数与腹主动脉钙化指数的相关性。方法回顾性选取2018年5月到2018年7月首都医科大学附属北京友谊医院收治的行能谱CT腹部平扫的肾内科患者30例,对其能谱腹部CT平扫数据进行分析。首先测量常规指标腹主动脉钙化指数,同时获得腹主动脉钙化容积重建的钙(水)基物质图,记录腹主动脉钙化体积、腹主动脉平均钙化浓度,并计算腹主动脉钙化评分,观察能谱CT血管钙化参数与腹主动脉钙化指数的相关性。结果腹主动脉钙化指数、钙化体积与腹主动脉钙化积分之间呈极强相关性(r> 0. 8),钙化平均浓度与腹主动钙化指数、钙化体积和腹主动脉钙化积分3个参数呈强正相关性(0. 6 Objective To discuss the correlation between gemstone spectral CT vascular calcification parameters and aortic calcification index. Methods Thirty patients were retrospectively selected in the department of nephrology of Beijing friendship hospital from May 2018 to July2018. Abdominal gemstone spectral CT scans were performed on all patients and the data were analyzed. Abdominal aortic calcification index was obtained from the CT scan. Diagram of calcium( water) base material was generated for the volume rendering images of abdominal aortic. Abdominal aortic calcification volume,mean concentration and calcification scores were recorded. The relationship between the aortic calcification index and vascular calcification parameters was analyzed. Results There was a strong correlation between the abdominal aortic calcification index,calcification volume and the calcification score( r > 0. 8). The mean calcium concentration was positively correlated with abdominal aortic calcification index,abdominal aortic calcification volume and calcification scores( 0. 6 < r < 0. 8). Conclusion Gemstone spectral CT is a reliable method to analyze the calcification of abdominal aorta,which can better reflect the characteristics of vascular calcification.
引文
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[2]刘艺涵,孔炜.血管中膜钙化的机制[J].生理学报,2016,68(5):592-610.
[3]Disthabanchong S,Boongird S.Role of different imaging modalities of vascular calcification in predicting outcomes in chronic kidney disease[J].World J Nephrol,2017,6(3):100-110.
[4]Mannelli L,Mac Donald L,Mancini M,et al.Dual energy computed tomography quantification of carotid plaques calcification:comparison between monochromatic and polychromatic energies with pathology correlation[J].Eur Radiol,2015,25(5):1238-1246.
[5]Nasr Allah MM,Nassef A,Elshaboni TH,et al.Comparing diffetent calcification scores to detect outcomes in chronic kidney disease patients with vascular calcification[J].Int J Cardiol,2016,220:884-889.
[6]Disthabanchong S,Vipattawat K,Phakdeekitcharoen B,et al.Abdominal aorta and pelvic artery calcifcations on plain radiographs may predict mortality in chronic kidney disease,hemodialysis and renal transplantation[J].Int Urol Nephrol,2018,50(2):355-364.
[7]Honkanen E,Kauppila L,Wikstr9m B,et al.Abdominal aortic calcification in dialysis patients:results of the CORD study[J].Nephrol Dial Transplant,2008,23(12):4009-4015.
[8]Criqui MH,Denenberg JO,Ix JH,et al.Calcium density of coronary artery plaque and risk of incident cardiovascular events[J].JAMA,2014,311(3):271-278.
[9]IHou ZH,Lu B,Gao Y,et al.Prognostic value of coronary CT angiography and calcium score for major adverse cardiac events in outpatients[J].JACC Cardiovasc Imaging,2012,5(10):990-999.