高通量血液透析治疗老年肾性骨病患者的临床研究
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摘要
目的:研究高通量血液透析治疗老年肾性骨病患者的临床疗效。方法:选定本院收治的100例老年肾性骨病(Renal Osteodystropl,ROD)患者,研究时段为2017年2-12月,在随机数字表法的分组原则下,分为研究组(50例,高通量血液透析)、对照组(50例,普通低通量透析),比较临床指标、治疗效果。结果:研究组β2-微球蛋白、磷显著较对照组低,钙、临床总有效率显著较对照组高,P <0.05。结论:高通量血液透析可有效改善老年ROD患者病情,提高血钙水平,效果显著,值得借鉴。
Objective: To study clinical efficacy of high throughput hemodialysis on elderly renal osteodystrophy. Methods: 100 cases were divided into two groups, 50 cases in each. The control group was given low flux hemodialysis; and the study group was given high throughput hemodialysis. Results: The β2-microglobulin and phosphorus in the study group were significantly lower than the control group;calcium and clinical total efficiency were significantly higher than the control group, P<0.05. Conclusion: High throughput hemodialysis on elderly renal osteodystrophy shows a good effect, increase blood calcium levels, and is worthy of promotion.
Objective: To study clinical efficacy of high throughput hemodialysis on elderly renal osteodystrophy. Methods: 100 cases were divided into two groups, 50 cases in each. The control group was given low flux hemodialysis; and the study group was given high throughput hemodialysis. Results: The β2-microglobulin and phosphorus in the study group were significantly lower than the control group;calcium and clinical total efficiency were significantly higher than the control group, P<0.05. Conclusion: High throughput hemodialysis on elderly renal osteodystrophy shows a good effect, increase blood calcium levels, and is worthy of promotion.
引文
[1]孙高中.高转运型肾性骨病患者实施高通量血液透析联合血液灌流对其临床症状及生化指标的影响[J].临床和实验医学杂志,2015,14(21):1825-1827.
[2]白丽萍.高通量血液透析串联血液灌流治疗老年肾性骨病患者的疗效研究[J].中外医学研究,2014,12(21):47-48.
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[5]安凌春,黄春泉.高通量血液透析与普通血液透析对肾性骨病患者相关因子的影响[J].白求恩医学杂志,2016,14(01):33-34.
[6]Fournier A,Oprisiu R,Hottelart C,et al.Renal osteodystrophy in dialysis patients:diagnosis and treatment[J].Artificial Organs,2015,22(07):530-557.
[7]洪义芬.用高通量血液透析联合血液灌流治疗老年肾性骨病的效果研究[J].当代医药论丛,2015,13(17):237-238.
[8]王夏莲,张久德,石丽丽.高通量血液透析治疗老年肾性骨病患者的疗效观察[J].医学临床研究,2017,34(10):2021-2022.
[9]Melek E,Aynac?S,Atm??B,et al.A rare manifestation of renal osteodystrophy in a non-compliant hemodialysis child:Questions[J]Pediatric Nephrology,2016,31(09):1449-1450.
[10]高震.高通量血液透析对血清FGF23、β2-微球蛋白及钙磷代谢的影响[J].中国现代医药杂志,2015,17(08):79-81.
[11]陈曦,臧丛生,于大川.高通量血液透析对尿毒症患者β2微球蛋白清除效果的临床疗效[J].中国老年学,2015,35(08):2237-2238.
[12]刘希宁,林崇亭,杨江成.高通量透析对肾性骨病患者血清成纤维细胞生长因子-23及骨代谢的影响[J].滨州医学院学报,2015,38(02):88-90.
[2]白丽萍.高通量血液透析串联血液灌流治疗老年肾性骨病患者的疗效研究[J].中外医学研究,2014,12(21):47-48.
[3]樊均明.肾脏疾病[M].北京:人民卫生出版社,2008.
[4]葛敬标.比较普通血液透析和高通量血液透析对肾性骨病相关因子的影响[J].中国医师进修杂志,2014,37(05):52-54.
[5]安凌春,黄春泉.高通量血液透析与普通血液透析对肾性骨病患者相关因子的影响[J].白求恩医学杂志,2016,14(01):33-34.
[6]Fournier A,Oprisiu R,Hottelart C,et al.Renal osteodystrophy in dialysis patients:diagnosis and treatment[J].Artificial Organs,2015,22(07):530-557.
[7]洪义芬.用高通量血液透析联合血液灌流治疗老年肾性骨病的效果研究[J].当代医药论丛,2015,13(17):237-238.
[8]王夏莲,张久德,石丽丽.高通量血液透析治疗老年肾性骨病患者的疗效观察[J].医学临床研究,2017,34(10):2021-2022.
[9]Melek E,Aynac?S,Atm??B,et al.A rare manifestation of renal osteodystrophy in a non-compliant hemodialysis child:Questions[J]Pediatric Nephrology,2016,31(09):1449-1450.
[10]高震.高通量血液透析对血清FGF23、β2-微球蛋白及钙磷代谢的影响[J].中国现代医药杂志,2015,17(08):79-81.
[11]陈曦,臧丛生,于大川.高通量血液透析对尿毒症患者β2微球蛋白清除效果的临床疗效[J].中国老年学,2015,35(08):2237-2238.
[12]刘希宁,林崇亭,杨江成.高通量透析对肾性骨病患者血清成纤维细胞生长因子-23及骨代谢的影响[J].滨州医学院学报,2015,38(02):88-90.