连续性血液净化治疗重症脓毒症的疗效观察
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摘要
目的观察分析在临床中对重症脓毒症患者行连续性血液净化治疗的效果。方法择取98例重症脓毒症患者,将随机数字表法作为分组依据,均分为49例甲组、49例乙组,予以甲组患者行常规方式治疗,予以乙组患者行连续性血液净化方式治疗,对比临床效果。结果治疗后,乙组各项指标均显著优于甲组(P<0.05);甲组临床治疗总有效率为75.51%,乙组为93.87%,经对比乙组临床治疗总有效率明显更高(P<0.05)。结论针对重症脓毒症患者而言,对其行连续性血液净化治疗是一种有效的方式,在临床中的应用意义重大。
Objective To observe and analyze the effect of continuous blood purification treatment in patients with severe sepsis in clinical practice. Methods 98 patients with severe sepsis were selected. The random number table method was used as the grouping basis. They were divided into 49 cases of group A and 49 cases of group B. The patients in group A were treated by routine treatment, while patients in group B were treated by continuous blood purification, and the clinical effects were compared. Results After treatment, the indexes of group B were significantly better than group A(P<0.05). The total effective rate of group A was 75.51%, and that of group B was 93.87%. The total effective rate of group B was significantly higher(P<0.05). Conclusion For patients with severe sepsis, continuous blood purification treatment is an effective way, and its application in clinical is of great significance.
Objective To observe and analyze the effect of continuous blood purification treatment in patients with severe sepsis in clinical practice. Methods 98 patients with severe sepsis were selected. The random number table method was used as the grouping basis. They were divided into 49 cases of group A and 49 cases of group B. The patients in group A were treated by routine treatment, while patients in group B were treated by continuous blood purification, and the clinical effects were compared. Results After treatment, the indexes of group B were significantly better than group A(P<0.05). The total effective rate of group A was 75.51%, and that of group B was 93.87%. The total effective rate of group B was significantly higher(P<0.05). Conclusion For patients with severe sepsis, continuous blood purification treatment is an effective way, and its application in clinical is of great significance.
引文
[1]汪永斌,姬晓伟,占林兵.连续性血液净化治疗29例重症脓毒血症的疗效观察[J].中华全科医学,2016,14(4):580-582.
[2]蔡莉芬,张建集,董建霞.连续性血液净化治疗重症脓毒症合并应激性心肌病疗效分析[J].中国医药导刊,2016,18(5):458-459.
[3]霍志荣,杨世杰.参芪扶正注射液联合连续性血液净化治疗重症脓毒症的临床研究[J].现代中西医结合杂志,2017,26(7):756-758.
[4]俸小飞,邓琳,黄华.连续性血液净化治疗重症脓毒症的微循环及免疫改善效果分析[J].标记免疫分析与临床,2017,24(8):925-928.
[5]江贤威.连续性血液净化治疗重症脓毒症合并应激性心肌病的临床效果观察[J].临床合理用药杂志,2016,9(23):81-82.
[6]周瑞祥,翁方中,戴伟.严重脓毒症早期应用连续性血液净化的时机及其器官保护作用:一项随机双盲对照研究[J].中华危重病急救医学,2016,28(3):241-245.
[7]杨洪光,李峰,邹颋.连续性血液净化对脓毒症患者免疫功能及预后的影响[J].当代医学,2016,22(33):54-55.
[8]黄小甜.连续性血液净化治疗ICU重症脓毒血症的临床疗效及安全性评价[J].齐齐哈尔医学院学报,2017,38(18):2150-2151.
[9]罗醒政,王涛,郭敏.连续性血液净化对高降钙素原水平脓毒症患者的影响[J].内科急危重症杂志,2016,22(2):113-115.
[10]罗家庆.连续性血液净化应用于ICU重症脓毒血症治疗临床疗效及安全性评价[J].中国实用医药,2016,11(9):124-125.
[11]宋付民.探究连续性血液净化应用在重症脓毒血症患者治疗中的临床价值[J].临床医药文献电子杂志,2016,3(34):6752-6753.
[12]问军锋.连续性血液净化治疗腹腔感染和肺部感染引起脓毒症患者临床效果观察[J].临床肺科杂志,2017,22(2):307-309.
[13]王孛,陈力,孙荣距.连续性血液净化治疗严重脓毒症患者临床疗效分析[J].中国急救复苏与灾害医学杂志,2016,11(5):462-465.
[14]闫笛,宋岩,谭博.连续性血液净化疗法对重症脓毒血症患者疗效及炎症因子的影响[J].当代医学,2017,23(6):27-28.
[15]孙锡同.连续性血液净化治疗腹腔感染和肺部感染引起脓毒症患者临床效果分析[J].临床医药文献电子杂志,2017,4(67):13143-13144.
[16]Putzu A,Fang MX,Boscolo BM,et al.Blood purification with continuous venovenous hemofiltration in patients with sepsis or acute respiratory distress syndrome.A systematic review and meta-analysis of randomized evidence[J].Minerva Anestesiologica,2017,83(8):867-877.
[17]Schorr C,Odden A,Evans L,et al.Implementation of a multicenter performance improvement program for early detection and treatment of severe sepsis in general medical-surgical wards[J].Journal of Hospital Medicine,2016,11(S1):S32-S39.
[18]Arends S,Defosse J,Diaz C,et al.Successful treatment of severe Clostridium difficile infection by administration of crushed fidaxomicin via a nasogastric tube in a critically ill patient[J].International Journal of Infectious Diseases,2017,55(55):27-28.
[2]蔡莉芬,张建集,董建霞.连续性血液净化治疗重症脓毒症合并应激性心肌病疗效分析[J].中国医药导刊,2016,18(5):458-459.
[3]霍志荣,杨世杰.参芪扶正注射液联合连续性血液净化治疗重症脓毒症的临床研究[J].现代中西医结合杂志,2017,26(7):756-758.
[4]俸小飞,邓琳,黄华.连续性血液净化治疗重症脓毒症的微循环及免疫改善效果分析[J].标记免疫分析与临床,2017,24(8):925-928.
[5]江贤威.连续性血液净化治疗重症脓毒症合并应激性心肌病的临床效果观察[J].临床合理用药杂志,2016,9(23):81-82.
[6]周瑞祥,翁方中,戴伟.严重脓毒症早期应用连续性血液净化的时机及其器官保护作用:一项随机双盲对照研究[J].中华危重病急救医学,2016,28(3):241-245.
[7]杨洪光,李峰,邹颋.连续性血液净化对脓毒症患者免疫功能及预后的影响[J].当代医学,2016,22(33):54-55.
[8]黄小甜.连续性血液净化治疗ICU重症脓毒血症的临床疗效及安全性评价[J].齐齐哈尔医学院学报,2017,38(18):2150-2151.
[9]罗醒政,王涛,郭敏.连续性血液净化对高降钙素原水平脓毒症患者的影响[J].内科急危重症杂志,2016,22(2):113-115.
[10]罗家庆.连续性血液净化应用于ICU重症脓毒血症治疗临床疗效及安全性评价[J].中国实用医药,2016,11(9):124-125.
[11]宋付民.探究连续性血液净化应用在重症脓毒血症患者治疗中的临床价值[J].临床医药文献电子杂志,2016,3(34):6752-6753.
[12]问军锋.连续性血液净化治疗腹腔感染和肺部感染引起脓毒症患者临床效果观察[J].临床肺科杂志,2017,22(2):307-309.
[13]王孛,陈力,孙荣距.连续性血液净化治疗严重脓毒症患者临床疗效分析[J].中国急救复苏与灾害医学杂志,2016,11(5):462-465.
[14]闫笛,宋岩,谭博.连续性血液净化疗法对重症脓毒血症患者疗效及炎症因子的影响[J].当代医学,2017,23(6):27-28.
[15]孙锡同.连续性血液净化治疗腹腔感染和肺部感染引起脓毒症患者临床效果分析[J].临床医药文献电子杂志,2017,4(67):13143-13144.
[16]Putzu A,Fang MX,Boscolo BM,et al.Blood purification with continuous venovenous hemofiltration in patients with sepsis or acute respiratory distress syndrome.A systematic review and meta-analysis of randomized evidence[J].Minerva Anestesiologica,2017,83(8):867-877.
[17]Schorr C,Odden A,Evans L,et al.Implementation of a multicenter performance improvement program for early detection and treatment of severe sepsis in general medical-surgical wards[J].Journal of Hospital Medicine,2016,11(S1):S32-S39.
[18]Arends S,Defosse J,Diaz C,et al.Successful treatment of severe Clostridium difficile infection by administration of crushed fidaxomicin via a nasogastric tube in a critically ill patient[J].International Journal of Infectious Diseases,2017,55(55):27-28.