化浊明目汤治疗玻璃体混浊及对患者眼底及血流变指标的影响
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摘要
目的:观察自拟化浊明目汤治疗玻璃体混浊的疗效及对患者眼底、视网膜血流动力学指标与血流变指标的影响。方法:选取90例玻璃体混浊患者作为研究资料,随机均分为对照组与观察组,对照组采取碘化钾离子导入治疗,观察组于对照组治疗的基础上给予自拟化浊明目汤治疗;治疗一个疗程后,对比两组临床疗效,观察两组治疗前后眼底病变程度以及视网膜中心动脉血流动力学指标、血液流变学(血流变)指标的变化情况。结果:观察组临床总有效率84.44%,对照组为62.22%;观察组整体疗效水平优于对照组(P<0.05)。治疗后两组眼底病变程度均较前减轻,组内对比差异具有统计学意义(P<0.05);治疗后观察组眼底病变程度较对照组轻,组间对比差异具有统计学意义(P<0.05)。治疗后两组各项血流变指标均较前改善,组内对比差异具有统计学意义(P<0.05);治疗后观察组各项血流变指标较对照组理想,组间对比差异具有统计学意义(P<0.05)。治疗后两组各项视网膜中央动脉血流动力学指标均较前改善,组内对比差异具有统计学意义(P<0.05);治疗后观察组上述指标均较对照组理想,组间对比差异具有统计学意义(P<0.05)。结论:自拟化浊明目汤对于玻璃体混浊疗效理想,能够更有效的降低眼底病变程度,改善患者血流变指标与视网膜中心动脉血流动力学指标。
objective:Observe the effect of Huazhuo Mingmu decoction on vitreous turbidity and its effect on patients' fundus,retinal hemodynamics index and blood rheological index.Methods:Selection 90 patients with vitreous opacity as research materials,randomly divided into control group and observation group,control group treated with potassium iodide ion import,on the basis of the observation group in the control group treatment to give the Huazhuo Mingmu decoction;treatment after a period of treatment,compared two groups of clinical curative effect,observe two groups before and after treatment fundus lesions and center of the retina arterial blood flow mechanics index,blood rheology(showed)the changes of the indicators.Results:The total clinical efficiency of the observation group was 84.44%,and the control group was 62.22%.The overall effect of the observation group was better than that of the control group(P<0.05).After treatment,the level of fundus lesions in both groups was lower than before(P<0.05).After treatment,the level of fundus lesions in the observation group was lower than that in the control group(P<0.05).The blood rheological indexes of the two groups were better than those in the control group(P<0.05).After the treatment,both of the two groups of the retinal arterial blood flow mechanical indicators were better than the previous ones,and the observation group was all better than the control group(P<0.05).Conclusion:Huazhuo Mingmu decoction is ideal for the treatment of vitreous turbidity,which can effectively reduce the degree of fundus lesion,improve the blood flow index and the arterial blood flow mechanical index of the retinal center.
objective:Observe the effect of Huazhuo Mingmu decoction on vitreous turbidity and its effect on patients' fundus,retinal hemodynamics index and blood rheological index.Methods:Selection 90 patients with vitreous opacity as research materials,randomly divided into control group and observation group,control group treated with potassium iodide ion import,on the basis of the observation group in the control group treatment to give the Huazhuo Mingmu decoction;treatment after a period of treatment,compared two groups of clinical curative effect,observe two groups before and after treatment fundus lesions and center of the retina arterial blood flow mechanics index,blood rheology(showed)the changes of the indicators.Results:The total clinical efficiency of the observation group was 84.44%,and the control group was 62.22%.The overall effect of the observation group was better than that of the control group(P<0.05).After treatment,the level of fundus lesions in both groups was lower than before(P<0.05).After treatment,the level of fundus lesions in the observation group was lower than that in the control group(P<0.05).The blood rheological indexes of the two groups were better than those in the control group(P<0.05).After the treatment,both of the two groups of the retinal arterial blood flow mechanical indicators were better than the previous ones,and the observation group was all better than the control group(P<0.05).Conclusion:Huazhuo Mingmu decoction is ideal for the treatment of vitreous turbidity,which can effectively reduce the degree of fundus lesion,improve the blood flow index and the arterial blood flow mechanical index of the retinal center.
引文
[1]曾繁丽,王昭霞,罗霁菡,等.综合性心理干预对YAG激光治疗生理性玻璃体混浊的作用研究[J].重庆医科大学学报,2017,42(10):1324-1328.
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[11]薛晓辉.VEGF和bFGF在增生性玻璃体视网膜病变患者玻璃体中的表达及意义[J].陕西医学杂志,2016,45(6):707-708,719.
[12]秦常军,梁丽娜.和血明目片联合羟苯磺酸钙胶囊口服治疗玻璃体混浊疗效观察[J].世界最新医学信息文摘,2015,15(25):82-83.
[13]郁肆青,郑志.玻璃体视网膜交界面疾病发病因素的研究进展[J].中华眼底病杂志,2015,31(1):104-108.
[14]祁岗,陈彦群,朱明娟,等.加减退翳明目汤辅助90锶敷贴治疗角膜云翳的疗效观察[J].陕西中医,2016,37(12):1638-1639.
[15]王雪.明目清浊汤治疗玻璃体浑浊的疗效分析[J].中国医药指南,2017,15(16):201-202.
[2]罗霁菡,匡毅,赵琳,等.YAG激光治疗生理性玻璃体混浊的临床研究[J].国际眼科杂志,2016,16(9):1753-1755.
[3]黎佳敏,董玉.三仁汤在眼科的应用研究进展[J].云南中医中药杂志,2016,37(12):95-97.
[4]雷洪涛.中西医结合治疗玻璃体积血临床研究[J].中医学报,2017,32(10):1997-2000.
[5]梁晓凡.和血明目片联合羟苯磺酸钙胶囊口服治疗玻璃体混浊的疗效[J].中国处方药,2016,14(11):70-71.
[6]邓向明.氨碘肽注射液在近视性玻璃体混浊治疗中的应用分析[J].黑龙江医药,2016,29(6):1142-1144.
[7]孙宁.复方碘化钾滴眼液联合氨碘肽滴眼液治疗玻璃体混浊的效果观察[J].泰山医学院学报,2015,36(4):419-420.
[8]张可.氨碘肽注射液治疗玻璃体混浊的临床疗效[J].临床合理用药杂志,2015,8(9C):99-100.
[9]张祝强,左韬,王梦楠,等.中西医结合治疗老年性湿性黄斑变性34例临床观察[J].辽宁医学杂志,2013,27(3):126-127.
[10]陈晓刚,董冠斌,黄江丽.明目清障汤联合碘化钾离子导入对玻璃体混浊患者视力及眼底的改善作用[J].新中医,2016,48(11):143-145.
[11]薛晓辉.VEGF和bFGF在增生性玻璃体视网膜病变患者玻璃体中的表达及意义[J].陕西医学杂志,2016,45(6):707-708,719.
[12]秦常军,梁丽娜.和血明目片联合羟苯磺酸钙胶囊口服治疗玻璃体混浊疗效观察[J].世界最新医学信息文摘,2015,15(25):82-83.
[13]郁肆青,郑志.玻璃体视网膜交界面疾病发病因素的研究进展[J].中华眼底病杂志,2015,31(1):104-108.
[14]祁岗,陈彦群,朱明娟,等.加减退翳明目汤辅助90锶敷贴治疗角膜云翳的疗效观察[J].陕西中医,2016,37(12):1638-1639.
[15]王雪.明目清浊汤治疗玻璃体浑浊的疗效分析[J].中国医药指南,2017,15(16):201-202.