胸腰椎压缩骨折后路内固定术后复位丢失的临床研究
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摘要
目的观察经皮角度椎弓根螺钉修复急性胸腰椎压缩骨折术后复位丢失最大发生的时间段,并分析对临床效果影响的相关因素。方法回顾分析2013年7月至2016年1月通过经皮角度椎弓根螺钉修复急性胸腰椎压缩骨折患者共78例,男57例,女21例;年龄21~65岁,平均(48±12)岁。所有患者于术后8~10个月间取出内固定物,于术后3个月、6个月、取内固定时、取出内固定后3个月、1年、2年、末期进行随访。测量不同时间点X线片上病椎前缘高度百分比(anterior vertebral height,AVH)、后缘高度百分比(posterior vertebral height,PVH)、后凸角(Cobb角)。使用视觉模拟评分(visual analogue scale,VAS)及Oswestry功能障碍指数(Oswestry disability index,ODI)评价腰背部疼痛及功能状况。结果患者随访时间2.8~4.9年,平均随访时间3.6年。术后即刻及末次随访时病椎前后缘高度百分比、后凸角较术前明显改善,差异有统计学意义(P<0.01)。病椎前后缘高度、后凸角丢失随时间推移一直存在,其丢失最大发生在术后3个月及内固定取出后3个月内(组间ANOVA对比P<0.05,差异有统计学意义),内固定取出1年后复位丢失不大。末次随访患者腰背部平均ODI评分为(7.84±2.05)%,影响因素为术前AVH(回归系数B=-0.062,P=0.048)和末次随访AVH(B=-0.034,P=0.046),PVH、Cobb角度以及内固定取出前后各指标丢失值与ODI评分无相关性。末次随访平均VAS评分(2.25±0.58)分,与上述指标均无明显相关性。结论经皮角度椎弓根螺钉系统对于急性胸腰椎压缩骨折具有良好的畸形矫正能力和临床疗效,但在术后3个月及内固定取出后3个月内复位丢失最大,需要有效的预防。椎体前缘高度可以预测远期的手术效果,而不同时间段椎体少量的丢失并不影响这种治疗的效果。
        
引文
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