血清降钙素原、超敏C反应蛋白在急性阑尾炎诊断中的应用价值
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摘要
目的探讨血清降钙素原、超敏C反应蛋白在急性阑尾炎诊断中的应用价值。方法选取某院2016年2月～2018年2月收治的80例急性阑尾炎患者作为观察组,另选取同期在某院接受体检的80例健康者作为对照组,对所有研究者进行血清降钙素原和超敏C反应蛋白水平检测,比较两组的检测结果。结果观察组的血清降钙素原水平为(0.92±0.15)ng/ml,高于对照组的(0.08±0.02)ng/ml,差异有统计学意义(P<0.05)。观察组的超敏C反应蛋白水平为(17.68±2.36)mg/L,高于对照组的(4.82±1.14)mg/L,差异有统计学意义(P<0.05)。穿孔性阑尾炎患者血清降钙素原浓度、超敏C反应蛋白浓度明显高于单纯性阑尾炎、坏疽性及化脓性阑尾炎,差异有统计学意义(P<0.05)。急性阑尾炎患者治疗后的血清降钙素原、超敏C反应蛋白水平明显低于治疗前,差异有统计学意义(P<0.05)。结论血清降钙素原和超敏C反应蛋白既可区分健康人群和急性阑尾炎患者,也可将急性穿孔性阑尾炎与其他非穿孔性阑尾炎区分开来,可作为临床诊断该疾病的参考依据,为后续治疗方案的制订与执行奠定良好基础。
Objective To explore the application value of serum procalcitonin and hypersensitive C-reactive protein in the diagnosis of acute appendicitis. Methods A total of 80 patients with acute appendicitis treated in a hospital from February 2016 to February 2018 were selected as the observation group, and 80 healthy patients who received physical examination in a hospital during the same period were selected as the control group. Serum procalcitonin and hypersensitive C-reactive subjects levels of all subjects were tested, and the test results of the two groups were compared.Results The serum procalcitonin level in the observation group was(0.92±0.15) ng/ml, which was higher than(0.08±0.02) ng/ml in the control group, the difference was statistically significant(P<0.05). The level of hypersensitive C-reactive protein in the observation group was(17.68±2.36) mg/L, which was higher than(4.82±1.14) mg/L in the control group, the difference was statistically significant(P<0.05). The serum levels of procalcitonin and hypersensitive C-reactive protein in patients with perforated appendicitis were significantly higher than those in patients with simple appendicitis, gangrenous appendicitis and suppurative appendicitis respectively, and the differences were statistically significant(P<0.05). The serum levels of procalcitonin and hypersensitive C-reactive protein in patients with acute appendicitis after treatment were significantly lower than those before treatment, the differences were statistically significant(P<0.05). Conclusion Serum procalcitonin and hypersensitive C-reactive protein can distinguish between healthy people and patients with acute appendicitis, acute perforated appendicitis and will also be apart from the rest of the non perforated appendicitis, which can be used as a reference for clinical diagnosis of the disease, for the formulation and implementation of the follow-up treatment to lay the good foundation.
Objective To explore the application value of serum procalcitonin and hypersensitive C-reactive protein in the diagnosis of acute appendicitis. Methods A total of 80 patients with acute appendicitis treated in a hospital from February 2016 to February 2018 were selected as the observation group, and 80 healthy patients who received physical examination in a hospital during the same period were selected as the control group. Serum procalcitonin and hypersensitive C-reactive subjects levels of all subjects were tested, and the test results of the two groups were compared.Results The serum procalcitonin level in the observation group was(0.92±0.15) ng/ml, which was higher than(0.08±0.02) ng/ml in the control group, the difference was statistically significant(P<0.05). The level of hypersensitive C-reactive protein in the observation group was(17.68±2.36) mg/L, which was higher than(4.82±1.14) mg/L in the control group, the difference was statistically significant(P<0.05). The serum levels of procalcitonin and hypersensitive C-reactive protein in patients with perforated appendicitis were significantly higher than those in patients with simple appendicitis, gangrenous appendicitis and suppurative appendicitis respectively, and the differences were statistically significant(P<0.05). The serum levels of procalcitonin and hypersensitive C-reactive protein in patients with acute appendicitis after treatment were significantly lower than those before treatment, the differences were statistically significant(P<0.05). Conclusion Serum procalcitonin and hypersensitive C-reactive protein can distinguish between healthy people and patients with acute appendicitis, acute perforated appendicitis and will also be apart from the rest of the non perforated appendicitis, which can be used as a reference for clinical diagnosis of the disease, for the formulation and implementation of the follow-up treatment to lay the good foundation.
引文
[1]沈献芳.循证护理措施改善急性阑尾炎患者临床症状的效果评价[J].实用临床护理学电子杂志,2017,2(50):92-93.
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[4]李光明,李智锋,孙小会,等.多层螺旋CT征象诊断急性阑尾炎病理类型的价值[J].中国医学影像学杂志,2016,24(6):451-454.
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[8]徐晓红.B超对临床拟诊为急性阑尾炎患者的诊断及鉴别诊断意义[J].影像研究与医学应用,2017,1(4):108-109.
[9]赵倩,谢月群,张涛,等.降钙素原对脓毒症患者病情及预后的临床价值[J].中华急诊医学杂志,2016,25(7):937-943.
[10]李凤珠,胡然然,张晓蒙,等.降钙素原检测在儿童急性阑尾炎和肠系膜淋巴结炎鉴别诊断中的应用[J].实用临床医药杂志,2016,20(13):80-82.
[11]赖鑫,刘国梁,郑敏伟,等.急性阑尾炎患者血清降钙素原检测的临床意义探究[J].江西医药,2016,51(9):979-980.
[12]赵劭懂,陈俊,葛许华,等.降钙素原在儿科重症感染中的诊断价值[J].实用医学杂志,2016,32(2):300-303.
[13]杨权.免疫功能与超敏C反应蛋白(hs-CRP)检验对小儿支原体肺炎(MPP)的临床价值[J].医药前沿,2017,7(33):201.
[14]刘仕欣,钟伯年,杨伟煌.超敏C反应蛋白在评估支气管哮喘严重程度及疗效中的价值[J].临床肺科杂志,2016,21(5):937-939.
[15]曹雪.灯盏花素治疗急性脑梗死对超敏C反应蛋白(hsCRP)的影响及疗效机制[J].中国医药指南,2017,15(11):210-211.
[2]张学华.伴有腹泻症状急性阑尾炎的诊断探究[J].世界最新医学信息文摘,2016,16(44):129.
[3]陈国星.C-反应蛋白在急性阑尾炎诊断中的价值研究[J].黑龙江医学,2016,40(8):757-758.
[4]李光明,李智锋,孙小会,等.多层螺旋CT征象诊断急性阑尾炎病理类型的价值[J].中国医学影像学杂志,2016,24(6):451-454.
[5]关俊慧.急性阑尾炎术后切口的护理探讨[J].中西医结合心血管病电子杂志,2017,5(19):60-61.
[6]刘新爱,王同明,任月勤.三种病理类型急性阑尾炎患者的临床体征及多层螺旋CT征象特点差异性分析[J].中国CT和MRI杂志,2017,15(8):124-127.
[7]诸玮.以右下腹痛为首发症状的疑似急性阑尾炎患者的超声诊断分析[J].影像技术,2017,29(5):67-69.
[8]徐晓红.B超对临床拟诊为急性阑尾炎患者的诊断及鉴别诊断意义[J].影像研究与医学应用,2017,1(4):108-109.
[9]赵倩,谢月群,张涛,等.降钙素原对脓毒症患者病情及预后的临床价值[J].中华急诊医学杂志,2016,25(7):937-943.
[10]李凤珠,胡然然,张晓蒙,等.降钙素原检测在儿童急性阑尾炎和肠系膜淋巴结炎鉴别诊断中的应用[J].实用临床医药杂志,2016,20(13):80-82.
[11]赖鑫,刘国梁,郑敏伟,等.急性阑尾炎患者血清降钙素原检测的临床意义探究[J].江西医药,2016,51(9):979-980.
[12]赵劭懂,陈俊,葛许华,等.降钙素原在儿科重症感染中的诊断价值[J].实用医学杂志,2016,32(2):300-303.
[13]杨权.免疫功能与超敏C反应蛋白(hs-CRP)检验对小儿支原体肺炎(MPP)的临床价值[J].医药前沿,2017,7(33):201.
[14]刘仕欣,钟伯年,杨伟煌.超敏C反应蛋白在评估支气管哮喘严重程度及疗效中的价值[J].临床肺科杂志,2016,21(5):937-939.
[15]曹雪.灯盏花素治疗急性脑梗死对超敏C反应蛋白(hsCRP)的影响及疗效机制[J].中国医药指南,2017,15(11):210-211.