针药结合治疗急性缺血性脑卒中的疗效与安全性的系统评价
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摘要
目的系统评价针药结合治疗急性缺血性脑卒中的疗效及安全性。方法根据Cochrane系统评价方法,采用Revman5.3软件对纳入研究进行Meta分析。结果共纳入26项研究,共计2 275例急性缺血性脑卒中患者。Meta分析结果显示,针药联合治疗急性缺血性脑卒中较对照组可提高总有效率、改善神经功能缺损、提高日常生活活动能力,治疗较为安全。结论针药结合治疗急性缺血性脑卒中比单纯西药组有效安全。
Objective: To systematically evaluate the efficacy and safety of acupuncture combined with medicine on acute ischemic stroke. Methods: According to the Cochrane systematic evaluation method,the included studies were analyzed with Revman 5.3 software. Results: 2 275 cases with acute ischemic stroke were included in 26 studies. The results of meta-analysis showed that the combined acupuncture and drug therapy for acute ischemic stroke could improve the overall efficiency,neurological function defect,daily living ability and safety compared with the control group. Conclusion: Combined acupuncture and drug therapy is more effective and safer on acute ischemic stroke than Western medicine alone.
Objective: To systematically evaluate the efficacy and safety of acupuncture combined with medicine on acute ischemic stroke. Methods: According to the Cochrane systematic evaluation method,the included studies were analyzed with Revman 5.3 software. Results: 2 275 cases with acute ischemic stroke were included in 26 studies. The results of meta-analysis showed that the combined acupuncture and drug therapy for acute ischemic stroke could improve the overall efficiency,neurological function defect,daily living ability and safety compared with the control group. Conclusion: Combined acupuncture and drug therapy is more effective and safer on acute ischemic stroke than Western medicine alone.
引文
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[13]张军锋,郭长江,范远,等.针刺联合益智汤对脑梗死后认知障碍患者神经缺损功能及生活质量的影响[J].现代诊断与治疗,2017,28(11):1986-1987.
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[17]王迅.醒脑开窍针法联合扶正消栓汤对缺血性中风急性期患者hs-CRP的影响[J].针灸临床杂志,2016,32(4):17-19.
[18]宗振勇,耿连岐.针药结合治疗痰湿瘀阻型缺血性中风急性期临床疗效观察[J].内蒙古中医药,2017,36(16):120-121.
[19]曹峰.醒脑开窍针刺法联合通心络胶囊治疗83例急性脑梗死疗效观察[J].当代医学,2014,20(30):112-113.
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[21]曹军.尤瑞克林联合针刺对急性脑梗死病人S100B、MMP-9、TIMP-1及NIHSS评分的影响[J].中西医结合心脑血管病杂志,2017,15(11):1392-1395.
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[24]刘海花,魏雪涛,李淑杰,等.尿激酶联合“醒脑开窍”针刺法治疗急性脑梗死患者50例[J].中西医结合心脑血管病杂志,2015,13(5):653-655.
[25]曹改杰.醒脑开窍针刺与巴曲酶治疗脑梗死疗效及炎症细胞因子检测[J].上海针灸杂志,2013,32(8):621-623.
[26]柳学勇,郑佳英,段晓琼.醒脑开窍针法联合依达拉奉、纤溶酶治疗脑梗死急性期患者的疗效及对神经功能的影响[J].实用中西医结合临床,2017,17(5):121-122.
[27]柳晓莉,李卫华.醒脑开窍针法联合依达拉奉、纤溶酶治疗对脑梗死急性期患者神经功能的影响[J].内科,2016,11(4):525-528.
[28]Shimizu M,Yoshimura S,Takizawa S,et al.Effect of single nucleotide polymorphisms of the prostacyclin receptor gene on platelet activation in Japanese healthy subjects and patients with cerebral infarction[J].J Clin eurosci,2013,20(6):851-856.
[2]刘智宇,马彪.长春西汀结合“醒脑开窍”针法对急性缺血性脑卒中患者影响研究[J].针灸临床杂志,2016,32(4):27-30.
[3]李梦雪,洒玉萍.“醒脑开窍”针法治疗急性缺血性脑卒中的疗效及对MMP-9的影响[J].针灸临床杂志,2016,32(12):17-19.
[4]李珍,孙菊光.头皮针联合平衡针治疗缺血性中风急性期偏瘫30例[J].针灸临床杂志,2016,32(5):30-32.
[5]王海涛,方丽丽,谭占国.醒脑开窍针法对脑梗死急性期患者认知功能、运动功能及神经功能的影响[J].上海针灸杂志,2017,36(10):1168-1172.
[6]罗艳丽.急性脑梗死应用针灸治疗的临床效果评价[J].中国医药指南,2017,15(3):184-185.
[7]楚海波,张双勇,付俊丽.帖氏“飞针”法治疗急性脑梗死偏瘫:随机对照研究[J].中国针灸,2017,37(11):1153-1156.
[8]范崇桂,付国惠,闪海霞.通脑活络针刺法治疗急性脑梗死60例[J].南京中医药大学学报,2014,30(4):379-382.
[9]王宇,沐榕,陈莉.针刺对急性脑梗死患者血清S-100、hsCRP及神经功能的影响[J].上海针灸杂志,2014,33(4):296-298.
[10]刘德芳,赵波,吕云利,等.针刺治疗对脑梗死急性期患者血液循环、神经功能及日常生活能力的影响[J].现代中西医结合杂志,2015,24(28):3095-3097.
[11]倪浩斌,张萃艺,王华政.化痰通络法联合针灸醒脑开窍法治疗急性期脑梗死的临床观察[J].中国中医急症,2016,25(4):707-708.
[12]刘燕,孙培.针药结合治疗气虚血瘀证急性脑梗死疗效观察[J].针灸临床杂志,2015,31(12):20-22.
[13]张军锋,郭长江,范远,等.针刺联合益智汤对脑梗死后认知障碍患者神经缺损功能及生活质量的影响[J].现代诊断与治疗,2017,28(11):1986-1987.
[14]张贤明,余皓,王莎.扶正祛瘀化痰方联合针灸治疗急性缺血性脑卒中49例[J].河南中医,2015,35(6):1276-1278.
[15]李俊,王珊,陈瑶.针刺回阳九针穴联合加味补中益气汤治疗急性脑梗死的疗效观察[J].世界中医药,2017,12(2):398-400.
[16]杜奋飞,王艳.针刺结合星蒌承气汤治疗急性脑卒中临床观察[J].新中医,2015,47(6):246-247.
[17]王迅.醒脑开窍针法联合扶正消栓汤对缺血性中风急性期患者hs-CRP的影响[J].针灸临床杂志,2016,32(4):17-19.
[18]宗振勇,耿连岐.针药结合治疗痰湿瘀阻型缺血性中风急性期临床疗效观察[J].内蒙古中医药,2017,36(16):120-121.
[19]曹峰.醒脑开窍针刺法联合通心络胶囊治疗83例急性脑梗死疗效观察[J].当代医学,2014,20(30):112-113.
[20]肖艳春.急性脑梗死中医针药并用的治疗效果观察[J].中国实用神经疾病杂志,2017,20(1):49-50.
[21]曹军.尤瑞克林联合针刺对急性脑梗死病人S100B、MMP-9、TIMP-1及NIHSS评分的影响[J].中西医结合心脑血管病杂志,2017,15(11):1392-1395.
[22]李建坤,肖春风,韦哲,等.醒脑开窍针刺法配合尤瑞克林治疗急性脑梗死60例[J].河南中医,2013,33(7):1059-1060.
[23]王国祥,刘振彪,王献胜.醒脑开窍针法联合丁苯酞软胶囊治疗脑梗死的疗效观察[J].实用心脑肺血管病杂志,2013,21(8):54-55.
[24]刘海花,魏雪涛,李淑杰,等.尿激酶联合“醒脑开窍”针刺法治疗急性脑梗死患者50例[J].中西医结合心脑血管病杂志,2015,13(5):653-655.
[25]曹改杰.醒脑开窍针刺与巴曲酶治疗脑梗死疗效及炎症细胞因子检测[J].上海针灸杂志,2013,32(8):621-623.
[26]柳学勇,郑佳英,段晓琼.醒脑开窍针法联合依达拉奉、纤溶酶治疗脑梗死急性期患者的疗效及对神经功能的影响[J].实用中西医结合临床,2017,17(5):121-122.
[27]柳晓莉,李卫华.醒脑开窍针法联合依达拉奉、纤溶酶治疗对脑梗死急性期患者神经功能的影响[J].内科,2016,11(4):525-528.
[28]Shimizu M,Yoshimura S,Takizawa S,et al.Effect of single nucleotide polymorphisms of the prostacyclin receptor gene on platelet activation in Japanese healthy subjects and patients with cerebral infarction[J].J Clin eurosci,2013,20(6):851-856.