聚乳酸共聚增韧研究及其应用进展
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摘要
聚乳酸(PLA)具有优异的生物可降解性、可吸收性、良好的力学性能和可塑性,但也存在脆性大、冲击强度较低等缺陷。通过共聚增韧改性的方式能够有效地改善上述缺陷,扩大其应用范围。综述了PLA共聚增韧的主要方法及研究发展现状,主要包括嵌段共聚、接枝共聚和交联增韧3种方法。介绍了改性后聚乳酸的在医学和包装工业上的应用。对未来聚乳酸共聚增韧发展方向作出展望,开发绿色化的合成工艺、降低生产成本、提高聚合物稳定性、寻找更合适的改性单体是研究重点。
Polylactic acid(PLA)has fine biodegradable,bioabsorbable and fine mechanical properties,but it is brittle and has poor pliability.Thus,it has to be modified to enhance its pliability to expand its scope of application via the way of copolymerization.The main methods and recent research progress of toughening modification of PLA by copolymerization were reviewed,including the block copolymerization,grafting copolymerization and crosslinking toughening.The application of modified PLA in medicine and packaging industry was also introduced.In the future,it should focus on that the development of green chemical synthesis,reduced the production cost,improved the stability of the polymer and found a more suitable monomer.
Polylactic acid(PLA)has fine biodegradable,bioabsorbable and fine mechanical properties,but it is brittle and has poor pliability.Thus,it has to be modified to enhance its pliability to expand its scope of application via the way of copolymerization.The main methods and recent research progress of toughening modification of PLA by copolymerization were reviewed,including the block copolymerization,grafting copolymerization and crosslinking toughening.The application of modified PLA in medicine and packaging industry was also introduced.In the future,it should focus on that the development of green chemical synthesis,reduced the production cost,improved the stability of the polymer and found a more suitable monomer.
引文
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[24]Deng L D,Li A,Yao C,et al.Methoxy poly(ethylene glycol)-b-poly(L-lactic acid)copolymer nanoparticles as delivery vehicles for paclitaxel[J].Journal of Applied Polymer Science,2005,98(5):2116-2122.
[25]王勤,王传栋,刘阳,等.聚乙二醇改性聚乳酸嵌段共聚物的合成与亲水性研究[J].化工新型材料,2012,40(7):81-84.
[26]Suesat J,Phillips D A S,Wilding M A,et al.The influence of yarn-processing parameters on the tensile properties and structure of poly(L-lactic acid)fibres[J].Polymer,2003,44(19):5993-6002.
[27]卓仁禧,尹超,吴颖楠,等.聚乳酸眼科植入材料的制备及其降解性能[J].应用化学,1997(2):102-104.
[2]宋谋道,朱吉亮,张邦华,等.聚乙二醇改性聚乳酸的研究[J].高分子学报,1998(4):454-458.
[3]Cohn D,Hotovely-Salomon A.Designing biodegradable multiblock PCL/PLA thermoplastic elastomers[J].Biomaterials,2005,26(15):2297-2305.
[4]Cohn D,Hotovely-Salomon A.Biodegradable multiblock PEO/PLA thermoplastic elastomers:molecular designand properties[J].Polymer,2005,46(7):2068-2075.
[5]焦明立,郑瑾,杨凯,等.PLA/PEG多嵌段共聚物的合成与表征[J].中原工学院学报,2009,20(5):1671-6906.
[6]邹俊,魏芸,吴毅炳,等.聚乳酸/聚丁二酸丁二醇酯嵌段共聚物的合成与表征[J].塑料工业,2013,41(5):1005-5770.
[7]饶炬,龚飞荣,陈建定,等.环状碳酸酯共聚改性聚乳酸性能[J].华东理工大学学报,2009,35(2):1006-3008.
[8]李启蒸,张国艺,黄晋,等.结构可控的聚亚甲基/聚乳酸嵌段共聚物的合成及其性能研究[J].化学学报,2011,69(4):497-502.
[9]Odent J,Leclère P,Raquez J M,et al.Toughening of polylactide by tailoring phase-morphology with P[CL-co-LA]random copolyesters as biodegradable impact modifiers[J].European Polymer Journal,2013,49(4):914-922.
[10]Slivniak R.Lacticacid and ricinoleicacid based copolyesters[J].Macromolecules,2005,38(13):5545-5553.
[11]Bishai M,De S,Adhikari B,et al.Copolymerization of lactic acid for cost-effective PLA synthesis and studies on its improved characteristics[J].Food Sci.Biotechnol,2013,22(1S):73-77.
[12]Xiao Z,Wu B,Wu L,et al.Poly(L-lactic acid)-block-poly(butylene succinate-co-butylene adipate)multiblock copolymers:from synthesis to thermo-mechanical properties[J].Industrial&Engineering Chemistry Research,2014,53(9):3550-3558.
[13]Qi R,Luo M,Huang M.Synthesis of styrene-ethylene-butylene-styrene triblock copolymer-g-polylactic acid copolymer and its potential application as a toughener for polylactic acid[J].Journal of Applied Polymer Science,2011,120(5):2699-2706.
[14]Li C,Qiu X,Deng M,et al.The starch grafted poly(L-lactide)and the physical properties of its blending composites[J].Polymer,2005,46(15):5723-5729.
[15]彭少贤,池彩云,应继儒,等.丙烯酸接枝聚乳酸的初步研究[J].现代塑料加工应用,2006,18(4):19-21.
[16]彭朝荣,王静霞,陈竹平,等.聚-L-乳酸辐射接枝N-乙烯基吡咯烷酮的研究[J].辐射研究与辐射工艺学报,2009,27(2):75-78.
[17]赵宇超,张举,吴智华.甲基丙烯酸缩水甘油酯接枝聚乳酸共聚物的制备与表征[J].工程塑料应用,2014.42(1):1001-3539.
[18]Ding J,Chen S C,Wang X L,et al.Synthesis and properties of thermoplastic poly(vinyl alcohol)-graft-lactic acid copolymers[J].Industrial&Engineering Chemistry Research,2009,48(2):788-793.
[19]Zhong K H,Qiu X,Sun J,et al.Grafting polymerization of L-lactide on the surface of hydroxyapatite nano-crystals[J].Polymer,2004,45(19):6699-6706.
[20]Bhardwaj R,Mohanty A K.Modification of brittle polylactide by novel hyperbranched polymer-based nanostructures[J].Biomacromolecules,2007,8(8):2476-2484.
[21]Huang S,Sun H,Sun J,et al.Biodegradable tough blends of poly(L-lactide)and poly(castor oil)-poly(L-lactide)copolymer[J].Materials Letters,2014,133(73):87-90.
[22]Cannizzaro S M,Pandera A R,Langer R,et al.Anovel biotinylated degradable polymer for cell-interactive applications[J].Biotechnol and Bioengeng,1998,58(5):529-535.
[23]邓联东,姚芳莲,孙多先,等.聚乙二醇单甲醚-聚(D,L-乳酸)嵌段共聚物的研究[J].中国生物医学工程学报,2005,24(6):736-739.
[24]Deng L D,Li A,Yao C,et al.Methoxy poly(ethylene glycol)-b-poly(L-lactic acid)copolymer nanoparticles as delivery vehicles for paclitaxel[J].Journal of Applied Polymer Science,2005,98(5):2116-2122.
[25]王勤,王传栋,刘阳,等.聚乙二醇改性聚乳酸嵌段共聚物的合成与亲水性研究[J].化工新型材料,2012,40(7):81-84.
[26]Suesat J,Phillips D A S,Wilding M A,et al.The influence of yarn-processing parameters on the tensile properties and structure of poly(L-lactic acid)fibres[J].Polymer,2003,44(19):5993-6002.
[27]卓仁禧,尹超,吴颖楠,等.聚乳酸眼科植入材料的制备及其降解性能[J].应用化学,1997(2):102-104.