近视眼及远视眼在眼角膜生物力学研究中的作用
摘要
目的研究并比较近视眼、远视眼在眼角膜生物力学研究中的作用。方法选取2014年1月至2016年12月眼科门诊收治的60例近视眼、60例远视眼患者作为研究对象,分别将其设置为近视组、远视组,采用眼反应分析仪对2组患者角膜生物力学指标进行测量,比较2组患者等效球镜(spherical equivalent,SE)、角膜屈光力(Ave K)、中央角膜厚度(central corneal thickness,CCT)、眼压(intraocular pressure,IOP)、角膜阻力因子(corneal resistance factor,CRF)、角膜滞后量(corneal hysteresis,CH),并计算角膜生物力学参数的相关性。结果近视组与远视组等效球镜、角膜屈光力比较差异有统计学意义(P<0.05),其余各项参数比较差异均无统计学意义(P>0.05);等效球镜、角膜屈光力、眼压均与角膜生物力学参数无线性相关,中央角膜厚度与角膜阻力因子、角膜滞后量等角膜生物力学参数密切相关,且呈正相关;中央角膜厚度、角膜屈光力与非接触眼压计测得的眼压均密切相关,而与眼反应分析仪测得的眼压无线性相关。结论近视眼、远视眼患者的角膜生物力学参数受到其中央角膜厚度的影响,而不受眼压、角膜屈光状态等因素的影响,且近视或远视的角膜生物力学参数并不存在显著差异。
引文
1孙倩,周跃华.远视眼与近视眼角膜生物力学研究及眼压的比较.眼科新进展,2014,34:971-974.
2 Yu AY,Duan SF,Zhao YE,et al.Correlation between corneal biomechanical properties,applanation tonometry and direct intracameral tonometry.British journal of ophthalmology,2012,96:640-644.
3 吴含春,付玲玲.屈光度与不同眼球参数的关系分析.中国实用眼科杂志,2013,31:1204-1207.
4 肖信,刘伟民,黄建忠,等.角膜生物力学分析仪测量近视患者中央角膜厚度和眼压的准确性评价.中华实验眼科杂志,2016,34:340-344.
5 邓铮铮,李仕明,周跃华,等.近视人群角膜生物力学特性的变化及其影响因素.中华实验眼科杂志,2016,34:842-846.
6 侯杰,雷玉琳,郑秀云,等.近视眼角膜上皮厚度分布特点及其与角膜生物力学性能的关系.中华眼视光学与视觉科学杂志,2014,16:291-296.
7 Kara N,Altinkaynak H,Baz O,et al.Biomechanical evaluation of cornea in topographically normal relatives of patients with keratoconus.Cornea,2013,32:262-266.
8 阚菲菲,胡琦,崔静,等.角膜生物力学属性对角膜塑形镜效果的影响.中国斜视与小儿眼科杂志,2016,24:1-5.
9 毛欣杰,周杭帅,刘然,等.角膜塑形术后角膜生物力学属性研究.眼科,2012,21:381-383.
10 Niyazmand H,Ostadi Moghaddam H,Sedaghat MR,et al.Anterior segment changes following short-term reading and its correlation with corneal Biomechanical Characteristics.Ophthalmic&physiological optics:the journal of the British College of Ophthalmic Opticians(Optometrists),2013,33:592-596.
11 曹雪倩,张章,王林农,等.角膜生物力学测量及其临床应用新进展.医学研究生学报,2016,29:319-322.
12 Kozobolis V,Sideroudi H,Giarmoukakis A,et al.Corneal biomechanical properties and anterior segment parameters in forme fruste keratoconus.European journal of ophthalmology,2012,22:920-930.
13 吴迪,王雁.角膜屈光手术后角膜生物力学变化特点的研究进展.国际眼科纵览,2012,36:260-265.
14 魏升升,李勇,李晶,等.圆锥角膜与健康角膜生物力学的对比研究.中华眼科杂志,2016,52:669-673.
15 Teke MY,Elgin U,Sen E,et al.Early effects of pars plana vitrectomy combined with intravitreal gas tamponade on corneal biomechanics.Ophthalmologica:International Journal of Ophthalmology=Journal International d'Ophtalmologie,2013,229:137-141.
16 Ali M,Kamiya K,Shimizu K,et al.Clinical evaluation of corneal biomechanical parameters after posterior chamber phakic intraocular lens implantation.Cornea,2014,33:470-474.
17 Acar BT,Akdemir MO,Acar S,et al.Corneal biomechanical properties in eyes with no previous surgery,with previous penetrating keratoplasty and with deep anterior lamellar keratoplasty.Japanese Journal of Ophthalmology,2013,57:85-89.
18 汪倩,王琳琳,张妍,等.角膜生物力学特性的测量方法研究现状.国际眼科杂志,2016,16:1840-1846.
19 宋沙沙,李军,宋慧,等.角膜生物力学测量研究进展.中国实用眼科杂志,2015,33:1193-1196.
20 Cankaya AB,Anayol A,Zcelik D,et al.Ocular response analyzer to assess corneal biomechanical properties in exfoliation syndrome and exfoliative glaucoma.Graefe’s archive for clinical and experimental ophthalmology:Albrecht von Graefes Archiv fur klinische und experimentelle Opthalmologie,2012,250:255-260.
21 Hon Y,Cheung SW,Cho P,et al.Repeatability of corneal biomechanical measurements in children wearing spectacles and orthokeratology lenses.Ophthalmic&physiological optics:the journal of the British College of Ophthalmic Opticians(Optometrists),2012,32:349-354.
22 高韶晖,方梦园,李士清,等.角膜生物力学与角巩膜物理特性及眼前段结构的相关研究.中国实用眼科杂志,2015,33:1341-1344.
23 Vázquez PRR,Delrivo M,Bonthoux FF,et al.Combining ocular response analyzer metrics for corneal biomechanical diagnosis.Journal of refractive surgery,2013,29:596-602.
24 杨铮,雷方,周瑞雅,等.眼压在儿童不同程度近视和眼轴变化中的作用.中华实验眼科杂志,2016,34:635-638.
25 Tranchina L,Lombardo M,Oddone F,et al.Influence of corneal biomechanical properties on intraocular pressure differences between an airpuff tonometer and the goldmann applanation tonometer.Journal of glaucoma,2013,22:416-421.
2 Yu AY,Duan SF,Zhao YE,et al.Correlation between corneal biomechanical properties,applanation tonometry and direct intracameral tonometry.British journal of ophthalmology,2012,96:640-644.
3 吴含春,付玲玲.屈光度与不同眼球参数的关系分析.中国实用眼科杂志,2013,31:1204-1207.
4 肖信,刘伟民,黄建忠,等.角膜生物力学分析仪测量近视患者中央角膜厚度和眼压的准确性评价.中华实验眼科杂志,2016,34:340-344.
5 邓铮铮,李仕明,周跃华,等.近视人群角膜生物力学特性的变化及其影响因素.中华实验眼科杂志,2016,34:842-846.
6 侯杰,雷玉琳,郑秀云,等.近视眼角膜上皮厚度分布特点及其与角膜生物力学性能的关系.中华眼视光学与视觉科学杂志,2014,16:291-296.
7 Kara N,Altinkaynak H,Baz O,et al.Biomechanical evaluation of cornea in topographically normal relatives of patients with keratoconus.Cornea,2013,32:262-266.
8 阚菲菲,胡琦,崔静,等.角膜生物力学属性对角膜塑形镜效果的影响.中国斜视与小儿眼科杂志,2016,24:1-5.
9 毛欣杰,周杭帅,刘然,等.角膜塑形术后角膜生物力学属性研究.眼科,2012,21:381-383.
10 Niyazmand H,Ostadi Moghaddam H,Sedaghat MR,et al.Anterior segment changes following short-term reading and its correlation with corneal Biomechanical Characteristics.Ophthalmic&physiological optics:the journal of the British College of Ophthalmic Opticians(Optometrists),2013,33:592-596.
11 曹雪倩,张章,王林农,等.角膜生物力学测量及其临床应用新进展.医学研究生学报,2016,29:319-322.
12 Kozobolis V,Sideroudi H,Giarmoukakis A,et al.Corneal biomechanical properties and anterior segment parameters in forme fruste keratoconus.European journal of ophthalmology,2012,22:920-930.
13 吴迪,王雁.角膜屈光手术后角膜生物力学变化特点的研究进展.国际眼科纵览,2012,36:260-265.
14 魏升升,李勇,李晶,等.圆锥角膜与健康角膜生物力学的对比研究.中华眼科杂志,2016,52:669-673.
15 Teke MY,Elgin U,Sen E,et al.Early effects of pars plana vitrectomy combined with intravitreal gas tamponade on corneal biomechanics.Ophthalmologica:International Journal of Ophthalmology=Journal International d'Ophtalmologie,2013,229:137-141.
16 Ali M,Kamiya K,Shimizu K,et al.Clinical evaluation of corneal biomechanical parameters after posterior chamber phakic intraocular lens implantation.Cornea,2014,33:470-474.
17 Acar BT,Akdemir MO,Acar S,et al.Corneal biomechanical properties in eyes with no previous surgery,with previous penetrating keratoplasty and with deep anterior lamellar keratoplasty.Japanese Journal of Ophthalmology,2013,57:85-89.
18 汪倩,王琳琳,张妍,等.角膜生物力学特性的测量方法研究现状.国际眼科杂志,2016,16:1840-1846.
19 宋沙沙,李军,宋慧,等.角膜生物力学测量研究进展.中国实用眼科杂志,2015,33:1193-1196.
20 Cankaya AB,Anayol A,Zcelik D,et al.Ocular response analyzer to assess corneal biomechanical properties in exfoliation syndrome and exfoliative glaucoma.Graefe’s archive for clinical and experimental ophthalmology:Albrecht von Graefes Archiv fur klinische und experimentelle Opthalmologie,2012,250:255-260.
21 Hon Y,Cheung SW,Cho P,et al.Repeatability of corneal biomechanical measurements in children wearing spectacles and orthokeratology lenses.Ophthalmic&physiological optics:the journal of the British College of Ophthalmic Opticians(Optometrists),2012,32:349-354.
22 高韶晖,方梦园,李士清,等.角膜生物力学与角巩膜物理特性及眼前段结构的相关研究.中国实用眼科杂志,2015,33:1341-1344.
23 Vázquez PRR,Delrivo M,Bonthoux FF,et al.Combining ocular response analyzer metrics for corneal biomechanical diagnosis.Journal of refractive surgery,2013,29:596-602.
24 杨铮,雷方,周瑞雅,等.眼压在儿童不同程度近视和眼轴变化中的作用.中华实验眼科杂志,2016,34:635-638.
25 Tranchina L,Lombardo M,Oddone F,et al.Influence of corneal biomechanical properties on intraocular pressure differences between an airpuff tonometer and the goldmann applanation tonometer.Journal of glaucoma,2013,22:416-421.