祛瘀化痰法治疗非酒精性脂肪性肝病35例临床观察
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摘要
目的观察自拟祛瘀化痰方治疗痰瘀互结型非酒精性脂肪性肝病(NAFLD)的临床疗效。方法将70例符合条件患者随机分为2组,对照组35例采用水飞蓟宾胶囊治疗,观察组在对照组基础上加服自拟祛瘀化痰方。2组疗程均为3个月,疗程结束后评定疗效。结果观察组在改善肝脏彩超、肝功能、血脂、临床症状方面均显著优于对照组,2组总有效率比较,差异具有统计学意义(P<0.05)。结论祛瘀化痰法治疗非酒精脂肪性肝病疗效显著。
Objective To observe the clinical effect of removing blo od stasis and resolving phlegm method in the treatment of nonalcoholic fatty liver disease. Methods 70 patients were randomly divided into two groups. 35 cases in the control group were treated with Shuifei Jibin capsule, and the observation group of 35 cases was given removing blood stasis and resolving phlegm method on the basis of the control group. The two groups of treatment were 3 months, and the efficacy was evaluated after the treatment. Results The observation group was significantly better than the control group in improving liver color, liver function, blood lipid and clinical symptoms, and the total effective rate of the two groups was statistically significant( P<0.05). Conclusion The curative effect of removing blood stasis and resolving phlegm method in treating non-alcoholic fatty liver disease is significant.
Objective To observe the clinical effect of removing blo od stasis and resolving phlegm method in the treatment of nonalcoholic fatty liver disease. Methods 70 patients were randomly divided into two groups. 35 cases in the control group were treated with Shuifei Jibin capsule, and the observation group of 35 cases was given removing blood stasis and resolving phlegm method on the basis of the control group. The two groups of treatment were 3 months, and the efficacy was evaluated after the treatment. Results The observation group was significantly better than the control group in improving liver color, liver function, blood lipid and clinical symptoms, and the total effective rate of the two groups was statistically significant( P<0.05). Conclusion The curative effect of removing blood stasis and resolving phlegm method in treating non-alcoholic fatty liver disease is significant.
引文
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[2] Fan J G,Falrell G C. Epidemiology of non-alcoholic fatty liver disease in China[J]. J Hepatol,2009,50(1):204-210.
[3]中华医学会肝病学分会脂肪肝和酒精性肝病学组.非酒精性脂肪性肝病诊疗指南(2010年修订版)[J].中华肝脏病杂志(电子版),2010,8(3):163-166.
[4]危北海,陈治水,李道本,等.非酒精性脂肪性肝病的中西医结合诊治方案(试行方案2008上海)[J].中国中西医结合消化杂志,2009,17(3):208-210.
[5]李琰.柴胡药理作用的研究进展[J].河北医学,2010,16(5):633-635.
[6]刘华钢,刘俊英,赖茂祥,等.郁金化学成分及药理作用的研究进展[J].广西中医学院学报,2008,11(2):81-83,86.
[7]张霄潇,李正勇,马玉玲,等.中药枳实的研究进展[J].中国中药杂志,2015,40(2):185-190.
[8] Kim G S,Park H J,Woo J H,et al. Citrus aurantium flavonoids inhibit adipogenesis through the Akt signaling pathway in 3T3-L1 cells[J]. BMC Complement Altern Med,2012,12:31.
[9]洪行球,沃兴德,何一中,等.半夏降血脂作用研究[J].浙江中医学院学报,1995,19(2):28-29,56.
[10]梁学清,李丹丹,黄忠威.茯苓药理作用研究进展[J].河南科技大学学报(医学版),2012,30(2):154-156.
[11]吴士杰,李秋津,肖学凤,等.山楂化学成分及药理作用的研究[J].药物评价研究,2010,33(4):316-319.
[12]方圣鼎,严修6,李静芳,等.有效成份垂盆草甙的分离与结构[J].科学通报,1979,30(9):431-432.
[13]付辛芳,刘晓红.丹参的药理作用与临床应用[J].中国药业,2006(1):76-77.
[14]张利.白芍的药理作用及现代研究进展[J].中国临床研究,2014,6(29):25-26.
[15]卢金清,黎强,李肖爽,等.决明子研究进展[J].湖北中医药大学学报,2014,16(4):124-126.
[16]邓胜国,邓泽元,黄丽.荷叶黄酮体外抗氧化活性的研究[J].食品科技,2006,32(7):274-276.