康柏西普玻璃体腔注射联合青光眼阀治疗新生血管性青光眼的临床观察
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摘要
目的观察全视网膜光凝后康柏西普玻璃体腔注射联合青光眼阀治疗新生血管性青光眼的临床疗效。方法临床选取24例来我院就诊的新生血管性青光眼患者,分为治疗组及对照组各12例(12只眼),治疗组给予全视网膜光凝后康柏西普玻璃体腔注射联合青光眼阀植入手术治疗和对照组全视网膜光凝后联合青光眼阀植入手术治疗。治疗后一周、一个月、二个月、三个月分别行最佳矫正视力、裂隙灯检查、眼压检查。结果治疗一个月后,治疗组总有效率为91.67%,对照组总有效率为58.33%,治疗三个月后治疗组与对照组总有效率比较差异有统计学意义(P<0.05),治疗组优于对照组。结论全视网膜光凝后康柏西普玻璃体腔注射联合青光眼阀植入治疗新生血管性青光眼疗效确切,保护残存视力,减少青光眼复发。
Objective To observe the clinical efficacy of intravitreal injection combined with Ahmed drainage vaIve impIantation in the treatment of neovascular glaucoma after panretinopathy photocoagulation(PRP). Methods Clinically collected the patient diagnosed as NVG,patients are divided into observed group(12 eyes) and contrasted group(12 eyes) at random, the observed group intravitreal injection combined with Ahmed drainage vaIve impIantation after panretinopathy photocoagulation(PRP),the contrasted group treated by the only Ahmed drainage vaIve impIantation after panretinopathy photocoagulation(PRP); After 1 week、1 month、2 months、3 months, according to the vision、slit lamp、non-contact to intraocular pressure, observation before and after treatment in patients of clinical effect. Results After 3 months,the total effectiveness of the observed group was 91.67%, the contrasted group was 58.33%, there were significant diffience between the two groups(P<0.05). Conclusions The combercept intravitreal injection combined with Ahmed drainage vaIve impIantation after panretinopathy photocoagulation in treat of neovascular glaucoma is safe and reliable.
Objective To observe the clinical efficacy of intravitreal injection combined with Ahmed drainage vaIve impIantation in the treatment of neovascular glaucoma after panretinopathy photocoagulation(PRP). Methods Clinically collected the patient diagnosed as NVG,patients are divided into observed group(12 eyes) and contrasted group(12 eyes) at random, the observed group intravitreal injection combined with Ahmed drainage vaIve impIantation after panretinopathy photocoagulation(PRP),the contrasted group treated by the only Ahmed drainage vaIve impIantation after panretinopathy photocoagulation(PRP); After 1 week、1 month、2 months、3 months, according to the vision、slit lamp、non-contact to intraocular pressure, observation before and after treatment in patients of clinical effect. Results After 3 months,the total effectiveness of the observed group was 91.67%, the contrasted group was 58.33%, there were significant diffience between the two groups(P<0.05). Conclusions The combercept intravitreal injection combined with Ahmed drainage vaIve impIantation after panretinopathy photocoagulation in treat of neovascular glaucoma is safe and reliable.
引文
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[2] 魏鹏程(导师:高永峰).新生血管性青光眼的综合治疗分析.郑州大学硕士学位论文,2017-03.
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[4] 马金瑞,律鹏,张文芳.新生血管性青光眼不同治疗方法和疗效评价.国际眼科杂志,2018,18(12):2173.
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[6] 李雪丽(导师:周丽霞).全视网膜光凝联合葛芪复明Ⅲ号治疗糖尿病性视网膜病变的临床观察.黑龙江中医药大学硕士学位论文,2007-05-01.
[7] Chen KH, Wu CC, Roy S,et al. Increased interleukin-6 in aqueous humor of neovascular glaucoma[J] .Invest Ophthalmol Vis Sci 1999;40(11):2627-2632.
[8] 褚梦琪.视网膜静脉阻塞继发黄斑水肿的最新治疗进展. 眼视光学杂志中华实验眼科杂志,2018,36(1):66-67.
[9] 张爱平.玻璃体腔注射康柏西普联合小梁切除术及视网膜光凝治疗新生血管性青光眼,山西医学杂志,2018,47(15):1755.
[10] 赵瑞苓,高峰,刘都红,等.新生血管性青光眼治疗新思路.中华眼外伤职业眼病杂志,2018,40(8):608.
[2] 魏鹏程(导师:高永峰).新生血管性青光眼的综合治疗分析.郑州大学硕士学位论文,2017-03.
[3] 葛坚.眼科学.人民卫生出版社,2005,264.
[4] 马金瑞,律鹏,张文芳.新生血管性青光眼不同治疗方法和疗效评价.国际眼科杂志,2018,18(12):2173.
[5] 李凤鸣.眼科全书.人民卫生出版社,1996,1946-1947.
[6] 李雪丽(导师:周丽霞).全视网膜光凝联合葛芪复明Ⅲ号治疗糖尿病性视网膜病变的临床观察.黑龙江中医药大学硕士学位论文,2007-05-01.
[7] Chen KH, Wu CC, Roy S,et al. Increased interleukin-6 in aqueous humor of neovascular glaucoma[J] .Invest Ophthalmol Vis Sci 1999;40(11):2627-2632.
[8] 褚梦琪.视网膜静脉阻塞继发黄斑水肿的最新治疗进展. 眼视光学杂志中华实验眼科杂志,2018,36(1):66-67.
[9] 张爱平.玻璃体腔注射康柏西普联合小梁切除术及视网膜光凝治疗新生血管性青光眼,山西医学杂志,2018,47(15):1755.
[10] 赵瑞苓,高峰,刘都红,等.新生血管性青光眼治疗新思路.中华眼外伤职业眼病杂志,2018,40(8):608.