中医辨证联合长春西汀注射液治疗伴发眩晕的突发性聋的效果
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摘要
目的探讨中医辨证联合长春西汀注射液治疗伴发眩晕的突发性聋的临床效果。方法选取2016年10月～2018年10月我院收治的60例伴发眩晕的突发性聋患者作为研究对象,按照随机数字表法分为对照组(30例)和观察组(30例)。对照组采用静脉滴注长春西汀注射液治疗,观察组在对照组治疗的基础上结合中医辨证治疗。两组患者均连续治疗10 d。比较两组突发性聋和眩晕的治疗效果及治疗前后的纯音听阈。结果观察组患者突发性聋的治疗总有效率为66.7%,高于对照组的50.0%,差异有统计学意义(P<0.05);治疗后,两组患者的纯音听阈低于治疗前,观察组患者的纯音听阈低于对照组,差异均有统计学意义(P<0.05);观察组患者眩晕症状的治疗总有效率为83.3%,高于对照组的70.0%,差异有统计学意义(P<0.05)。结论中医辨证联合长春西汀注射液治疗伴发眩晕的突发性聋效果优于单纯西药治疗,具有一定的临床推广应用价值。
Objective To explore the clinical effect of TCM syndrome differentiation combined with Vinpocetine Injection in the treatment of sudden deafness with vertigo. Methods A total of 60 cases of sudden deafness accompanied with vertigo admitted to our hospital from October 2016 to October 2018 were selected as the study objects, they were randomly divided into control group(30 cases) and observation group(30 cases) according to random number table method. The control group was treated with intravenous Vinpocetine Injection, while the observation group was treated with TCM syndrome differentiation on the basis of the control group. Two groups of patients were treated continuously for 10 days. The therapeutic effect of sudden deafness and vertigo and pure tone hearing threshold before and after treatment were compared between the two groups. Results The total effective rate of treatment for sudden deafness in the observation group was 66.7%, which was higher than 50.0% in the control group, the difference was significant(P<0.05). After treatment, the pure tone hearing threshold of the two groups was lower than that before treatment, and the pure tone hearing threshold of the observation group was lower than that of the control group, the differences were statistically significant(P<0.05). The total effective rate of vertigo symptoms in the observation group was 83.3%, which was higher than 70.0% in the control group, the difference was significant(P<0.05). Conclusion The effect of TCM syndrome differentiation combined with vinpocetine injection in treating sudden deafness with vertigo is better than that of Western medicine alone, which has certain clinical application value.
Objective To explore the clinical effect of TCM syndrome differentiation combined with Vinpocetine Injection in the treatment of sudden deafness with vertigo. Methods A total of 60 cases of sudden deafness accompanied with vertigo admitted to our hospital from October 2016 to October 2018 were selected as the study objects, they were randomly divided into control group(30 cases) and observation group(30 cases) according to random number table method. The control group was treated with intravenous Vinpocetine Injection, while the observation group was treated with TCM syndrome differentiation on the basis of the control group. Two groups of patients were treated continuously for 10 days. The therapeutic effect of sudden deafness and vertigo and pure tone hearing threshold before and after treatment were compared between the two groups. Results The total effective rate of treatment for sudden deafness in the observation group was 66.7%, which was higher than 50.0% in the control group, the difference was significant(P<0.05). After treatment, the pure tone hearing threshold of the two groups was lower than that before treatment, and the pure tone hearing threshold of the observation group was lower than that of the control group, the differences were statistically significant(P<0.05). The total effective rate of vertigo symptoms in the observation group was 83.3%, which was higher than 70.0% in the control group, the difference was significant(P<0.05). Conclusion The effect of TCM syndrome differentiation combined with vinpocetine injection in treating sudden deafness with vertigo is better than that of Western medicine alone, which has certain clinical application value.
引文
[1]张聪,唐玲,杨晓琦,等.大剂量巴曲酶治疗平坦型和全聋型突发性聋的疗效观察[J].实用临床医药杂志,2017,21(7):150-151.
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[11]田波.针灸联合西药治疗突发性耳聋疗效观察[J].湖北中医杂志,2017,39(12):22-24.
[12]张浩然.突发性耳聋相关影响因素回顾性分析[J].中国卫生产业,2015,12(32):64-66.
[13]吴子明,张素珍,周娜,等.伴眩晕的突发性聋患者椭圆囊-球囊功能分析[J].听力及言语疾病杂志,2005,13(6):397-399.
[14]Edizer DT,Celebi O,Hamit B,et al.Recovery of idiopathic suddensensorineural hearing loss[J].J Int Adv Oto,2015,11(2):122-126.
[15]刘博,韩德民,张祎,等.伴有眩晕或头晕的突发性聋患者的临床疗效分析[J].中华耳鼻咽喉头颈外科杂志,2015,50(6):463-467.
[16]高峰,顾平,汪旭,等.地塞米松联合长春西汀和胞磷胆碱钠治疗突发性耳聋的临床疗效[J].现代药物与临床,2017,32(12):2417-2421.
[17]吴飞虎,朱丹华.通窍活血汤联合脑蛋白水解物治疗气滞血瘀型突发性耳聋的临床观察[J].中成药,2017,39(1):228-229.
[18]刘琴,姚行齐.突发性耳聋中医病因病机探析[J].中西医结合研究,2016,8(4):214-215.
[2]陈玉卿,朱婕,张磊.突发性耳聋患者血脂代谢及凝血功能的临床分析[J].山西医药杂志,2017,46(17):2095-2096.
[3]岳金静,冯顺治,王关琴,等.伴发眩晕的突发性耳聋患者临床特征及诊治分析[J].解放军医学院学报,2016,37(8):830-852.
[4]中华耳鼻咽喉头颈外科杂志编辑委员会.突发性耳聋诊断和治疗指南(2015)[J].中华耳鼻咽喉头颈外科科杂志,2015,50(6):443-447.
[5]王德鑑.中医耳鼻喉科学[M].5版.上海:上海科学技术出版社,1985:25-31.
[6]中华医学会耳鼻咽喉科学会,中华耳鼻咽喉科杂志编辑委员会.突发性耳聋的诊断依据和疗效分级标准[J].中华耳鼻咽喉科杂志,1997,32(2):72.
[7]Wang CT,Huang TW,Kuo SW,et al.Correlation between audiovesti bular fun ction tests and hearing outcomes in severe to profound sudden sens orineural he aring loss[J].Ear Hear,2009,30(1):110-114.
[8]刘蕊,张秀利.突发性耳聋(暴聋)组方用药规律的古代文献研究[J].新疆中医药,2017,20(6):36-39.
[9]伦杰,张亚楠,薛建军,等.突发性耳聋患者临床治疗效果及相关影响因素分析[J].中国耳鼻咽喉颅底外科杂志,2016,22(3):198-202.
[10]汪琼,陈其国,胡福云,等.突发性耳聋的流行病学调查[J].中外医学研究,2016,14(33):55-57.
[11]田波.针灸联合西药治疗突发性耳聋疗效观察[J].湖北中医杂志,2017,39(12):22-24.
[12]张浩然.突发性耳聋相关影响因素回顾性分析[J].中国卫生产业,2015,12(32):64-66.
[13]吴子明,张素珍,周娜,等.伴眩晕的突发性聋患者椭圆囊-球囊功能分析[J].听力及言语疾病杂志,2005,13(6):397-399.
[14]Edizer DT,Celebi O,Hamit B,et al.Recovery of idiopathic suddensensorineural hearing loss[J].J Int Adv Oto,2015,11(2):122-126.
[15]刘博,韩德民,张祎,等.伴有眩晕或头晕的突发性聋患者的临床疗效分析[J].中华耳鼻咽喉头颈外科杂志,2015,50(6):463-467.
[16]高峰,顾平,汪旭,等.地塞米松联合长春西汀和胞磷胆碱钠治疗突发性耳聋的临床疗效[J].现代药物与临床,2017,32(12):2417-2421.
[17]吴飞虎,朱丹华.通窍活血汤联合脑蛋白水解物治疗气滞血瘀型突发性耳聋的临床观察[J].中成药,2017,39(1):228-229.
[18]刘琴,姚行齐.突发性耳聋中医病因病机探析[J].中西医结合研究,2016,8(4):214-215.