祛痰化瘀法联合噻托溴铵雾化吸入治疗对COPD缓解期患者康复进程及肺功能的影响
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摘要
目的研究祛痰化瘀法联合噻托溴铵雾化吸入治疗对慢性阻塞性肺疾病(COPD)缓解期患者康复进程及肺功能的影响。方法选取我院2012年3月~2014年9月COPD缓解期患者84例作为研究对象,将患者随机分为观察组和对照组,每组42例,观察组采用祛痰化瘀法联合噻托溴铵雾化吸入治疗,对照组采用单纯噻托溴铵雾化吸入治疗,比较两组肺功能改善情况。结果观察组治疗后的1 s用力呼气容积(FEV1)为(2.34±0.59)L,高于对照组的(1.82±0.63)L(P<0.05)。结论祛痰化瘀法联合噻托溴铵雾化吸入治疗COPD缓解期患者,具有宣肃肺气、化痰理气、泻热祛淤的功效,可以缓解患者的临床症状,改善肺功能,同时提高患者的免疫力,加快康复进程。
Objective To study effects of expelling phlegm and relieving blood stasis principle combined with tiotropium bromide aerosol inhalation treatment on recovery process and lung function of patients with chronic obstructive pulmoriary disease(COPD) in remission. Methods 84 COPD patients in remission of our hospital from March 2012 to September 2014 were selected as the research objects, they were randomly divided intoobservation group and control group, 42 cases in each group, observation group was given expelling phlegm and relieving blood stasis principle combined with tiotropium bromide aerosol inhalation treatment, control group was given simple tiotropium bromide aerosol inhalation treatment, clinical efficacy and improvement of lung function of two groups were compared. Results The 1s forced expiratory volume(FEV1) in the observation group was(2.34±0.59) L, higher than that in the control group(1.82±0.63) L(P<0.05).Conclusion Expelling phlegm and relieving blood stasis principle combined with tiotropium bromide aerosol inhalation treatment for COPD patients in remission has the effects of xuansufeiqi, resolving phlegm, regulating qi, purging heat and removing silt, can relieve clinical symptoms and improve lung function, and improve patients' immunity, speed up recovery process.
Objective To study effects of expelling phlegm and relieving blood stasis principle combined with tiotropium bromide aerosol inhalation treatment on recovery process and lung function of patients with chronic obstructive pulmoriary disease(COPD) in remission. Methods 84 COPD patients in remission of our hospital from March 2012 to September 2014 were selected as the research objects, they were randomly divided intoobservation group and control group, 42 cases in each group, observation group was given expelling phlegm and relieving blood stasis principle combined with tiotropium bromide aerosol inhalation treatment, control group was given simple tiotropium bromide aerosol inhalation treatment, clinical efficacy and improvement of lung function of two groups were compared. Results The 1s forced expiratory volume(FEV1) in the observation group was(2.34±0.59) L, higher than that in the control group(1.82±0.63) L(P<0.05).Conclusion Expelling phlegm and relieving blood stasis principle combined with tiotropium bromide aerosol inhalation treatment for COPD patients in remission has the effects of xuansufeiqi, resolving phlegm, regulating qi, purging heat and removing silt, can relieve clinical symptoms and improve lung function, and improve patients' immunity, speed up recovery process.
引文
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[2]秦茵茵,吴国锋,黎锐发,等.吸入噻托溴铵对老年慢性阻塞性肺病患者肺功能与气道炎症的影响[J].中国老年学杂志,2013,33(2):249-251.
[3]中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华内科杂志,2007,46(1):254-261.
[4]郑筱萸.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002,57-58.
[5]郑苏群,王真,杨珺超.浅谈COPD表型与中医证型的相关性[J].浙江中医药大学学报,2014,38(8):1037-1040.
[6]张永梅,肖成志.中西医结合治疗对COPD急性加重期患者肺功能改善和免疫功能的影响[J].海南医学院学报,2015,21(1):73-76.
[7]吕志超,丁林.健脾益肾祛痰化瘀通络法治疗慢性阻塞性肺疾病稳定期40例临床观察[J].河北中医,2014,36(4):514-515.
[8]相洁.清肺祛痰化瘀法治疗慢性阻塞性肺疾病32例[J].陕西中医,2013,34(6):697-699.