头孢菌素类抗菌药物在预防阑尾炎术后切口感染的效果及超声表现探究
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摘要
目的:探究在阑尾炎术后患者预防切口感染中应用头孢菌素类抗菌药物的临床效果及超声表现。方法:抽取本院在2013年4月1日至2018年6月30日收治并实施阑尾炎术治疗的60例患者。对其采用头孢菌素类抗菌药物——头孢哌酮钠治疗,探究并分析头孢哌酮钠预防切口感染的临床效果及超声表现。结果:在对本次研究的35例单纯性阑尾炎患者与25例化脓性阑尾炎患者均采用头孢哌酮钠治疗后,两组临床总有效率分别为100%、96%,比较无统计学意义(P>0.05);两组术前、术后体温测量比较无统计学意义(P>0.05);在25例化脓性阑尾炎中,有1例(4.00%)患者出现切口感染,其超声表现为切口处皮下水肿、右下腹阑尾区周边脂肪与网膜明显增厚,回声增强,可见不规则积液。结论:在阑尾炎术后患者中有效应用头孢菌素类抗菌药物可达到预防切口感染的目的,并保障手术治疗效果。故具有较高应用价值。
Objective: To investigate the clinical effect and ultrasonic manifestation of cephalosporins in prevention of incision infection in postoperative appendicitis patients. Methods: 60 patients with appendicitis were selected from our hospital from April 1, 2013 to June 30, 2018. Cefoperazone sodium was used to treat cefoperazone sodium. The clinical effect and ultrasonic manifestation of cefoperazone sodium in prevention of incisional infection were investigated and analyzed. Results: After the treatment of cefoperazone sodium in 35 patients with simple appendicitis and 25 patients with suppurative appendicitis in this study, the total effective rate of the two groups was 100%, 96%. There was no significant difference between the two groups(P>0.05), and there was no significant difference in body temperature before and after operation between the two groups(P>0.05). Of the 25 cases of suppurative appendicitis, 1 case(4.00%) had incision infection. The ultrasonic findings were subcutaneous edema at the incision, thickening of fat and omentum around the right lower abdominal appendicitis, enhanced echo and irregular effusion. Conclusion: The effective use of cephalosporins in postoperative appendicitis patients can prevent incision infection and ensure the effect of surgical treatment. Therefore, it has high application value.
Objective: To investigate the clinical effect and ultrasonic manifestation of cephalosporins in prevention of incision infection in postoperative appendicitis patients. Methods: 60 patients with appendicitis were selected from our hospital from April 1, 2013 to June 30, 2018. Cefoperazone sodium was used to treat cefoperazone sodium. The clinical effect and ultrasonic manifestation of cefoperazone sodium in prevention of incisional infection were investigated and analyzed. Results: After the treatment of cefoperazone sodium in 35 patients with simple appendicitis and 25 patients with suppurative appendicitis in this study, the total effective rate of the two groups was 100%, 96%. There was no significant difference between the two groups(P>0.05), and there was no significant difference in body temperature before and after operation between the two groups(P>0.05). Of the 25 cases of suppurative appendicitis, 1 case(4.00%) had incision infection. The ultrasonic findings were subcutaneous edema at the incision, thickening of fat and omentum around the right lower abdominal appendicitis, enhanced echo and irregular effusion. Conclusion: The effective use of cephalosporins in postoperative appendicitis patients can prevent incision infection and ensure the effect of surgical treatment. Therefore, it has high application value.
引文
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[2]靳艳文,叶辉,李富宇,等.抗菌药物与手术治疗单纯性急性阑尾炎的系统评价[J].重庆医学,2017,46(09):1235-1239.
[3]王海飞,吴连平,孙国平.急性阑尾炎单病种临床路径抗菌药物成本-效果分析[J].中国医药,2016,11(07):1080-1083.
[4]祝孟川,曾永娟,刘登瑞,等.阑尾切除术与抗生素比较治疗急性单纯性阑尾炎疗效和安全性的Meta分析[J].中国循证医学杂志,2017,17(02):188-194.
[5]彭俊华,郑晓华,李群英,等.普外科患者术后抗菌药物应用对切口感染的影响研究[J].中华医院感染学杂志,2016,26(20):4664-4666.
[6]曹松山,陶兴茹,裴保方.儿童急性阑尾炎围术期抗菌药物合理应用的干预研究[J].中国药房,2016,27(32):4584-4586.
[7]周舟,葛驰宇,陈海燕.药师干预对急性阑尾炎儿童抗生素应用的临床研究[J].中国医院药学杂志,2016,36(03):236-240.
[8]徐汉英,肖艳平,肖华.阑尾切除术后腹腔感染的病原学[J].中国感染控制杂志,2017,16(07):647-649.