低能量激光对大鼠牙移动后复发的影响
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摘要
目的:建立低能量激光及其他干预措施下大鼠牙移动后复发曲线,探讨低能量激光在正畸保持过程中的作用。方法:60只Wistar大鼠随机分为4组,建立第一磨牙近中移动模型。4组分别进行以下处理:不施加任何措施、照射低能量激光、固定保持、固定保持加照射低能量激光,隔日进行3-shape三维扫描测量建立复发曲线,并对4组曲线进行重叠和描述性分析。结果:低能量激光组大鼠磨牙移动复发率显著高于基线组,固定保持加低能量激光组复发率显著低于保持组(P<0.01)。与保持组相比,固定保持加低能量激光组复发周期明显缩短。结论:大鼠磨牙主动矫治结束后,应用保持装置固定牙齿的位置并加以低能量激光照射,能够缩短保持期,减少复发。
Objective:To establish a recurrence curve after tooth movement in rats with low-energy laser and other interventions,and to explore the role of low-energy laser in orthodontic preservation.Methods:Sixty wistar rats were randomly divided into four groups.After the first molar proximal-to-medium movement model was established by the active treatment,the four groups were individually subjected with:no treatment(group B),low-energy laser irradiation(group L),fixed retention(group R),and fixed retention with low-energy laser irradiation(group RL).3-shape three-dimensional scans were performed every other day to establish a recurrence curve.Overlap and describe analysis of the four groups of curves were performed.Results:The recurrence rate of molar movement in group L was significantly higher than that in group B.The recurrence rate in RL group was significantly lower than that in group R(P<0.01).Compared with group R,the recurrence period was significantly shorter in group RL.Conclusion:After the active correction of the rat's molar,applying the holding device to fix the position of the tooth and applying low energy laser irradiation can shorten the retention period and reduce the recurrence.
Objective:To establish a recurrence curve after tooth movement in rats with low-energy laser and other interventions,and to explore the role of low-energy laser in orthodontic preservation.Methods:Sixty wistar rats were randomly divided into four groups.After the first molar proximal-to-medium movement model was established by the active treatment,the four groups were individually subjected with:no treatment(group B),low-energy laser irradiation(group L),fixed retention(group R),and fixed retention with low-energy laser irradiation(group RL).3-shape three-dimensional scans were performed every other day to establish a recurrence curve.Overlap and describe analysis of the four groups of curves were performed.Results:The recurrence rate of molar movement in group L was significantly higher than that in group B.The recurrence rate in RL group was significantly lower than that in group R(P<0.01).Compared with group R,the recurrence period was significantly shorter in group RL.Conclusion:After the active correction of the rat's molar,applying the holding device to fix the position of the tooth and applying low energy laser irradiation can shorten the retention period and reduce the recurrence.
引文
[1]林鹏,郭新星,魏竹亮.局部注射黄芪多糖对大鼠正畸牙保持阶段BMP-2表达的影响[J].口腔医学研究,2017,33(5)∶520-524
[2]Migliario M,Pittarella P,Fanuli M,et al.Laser-induced osteoblast proliferation is mediated by ROS production[J].Lasers Med Sci,2014,29(4)∶1463-1467
[3]Huertas RM,Lunabertos ED,Ramostorrecillas J,et al.Effect and clinical implications of the low-energy diode laser on bone cell proliferation[J].Bio Res Nurs,2014,16(2)∶191-196
[4]Matthias K,Christoffers AB,Britta W,et al.Effect of low-level GaAlAs laser irradiation on the proliferation rate of human periodontal ligament fibroblasts:anin vitro study[J].J Clin Periodontol,2003,30(30)∶353-358
[5]Habib FA,Gama SK,Ramalho LM,et al.Laser-induced alveolar bone changes during orthodontic movement:a histological study on rodents[J].Photomed Laser Surg,2010,28(6)∶823-830
[6]Kim YD,Kim SS,Kim SJ,et al.Low-level laser irradiation facilitates fibronectin and collagen type I turnover during tooth movement in rats[J].Lasers Med Sci,2008,25(1)∶25-31
[7]周骢,伍宝琴,朱中焰,等.正畸移动大鼠牙过程牙周组织中PLAP-1、BMP-2的表达及意义[J].口腔医学研究,2017,33(1)∶33-37
[8]赵鹏,金鑫,吴建刚,等.激光医学中准分子激光器能量检测的探讨[J].中国医疗设备,2014,29(5)∶131-133
[9]Shirazi M,Ahmad Akhoundi MS,Javadi E,et al.The effects of diode laser(660nm)on the rate of tooth movements:an animal study[J].Lasers Med Sci,2015,30(2)∶713-718
[10]Altan BA,Sokucu O,Ozkut MM,et al.Metrical and histological investigation of the effects of low-level laser therapy on orthodontic tooth movement[J].Lasers Med Sci,2012,27(1)∶131-140
[2]Migliario M,Pittarella P,Fanuli M,et al.Laser-induced osteoblast proliferation is mediated by ROS production[J].Lasers Med Sci,2014,29(4)∶1463-1467
[3]Huertas RM,Lunabertos ED,Ramostorrecillas J,et al.Effect and clinical implications of the low-energy diode laser on bone cell proliferation[J].Bio Res Nurs,2014,16(2)∶191-196
[4]Matthias K,Christoffers AB,Britta W,et al.Effect of low-level GaAlAs laser irradiation on the proliferation rate of human periodontal ligament fibroblasts:anin vitro study[J].J Clin Periodontol,2003,30(30)∶353-358
[5]Habib FA,Gama SK,Ramalho LM,et al.Laser-induced alveolar bone changes during orthodontic movement:a histological study on rodents[J].Photomed Laser Surg,2010,28(6)∶823-830
[6]Kim YD,Kim SS,Kim SJ,et al.Low-level laser irradiation facilitates fibronectin and collagen type I turnover during tooth movement in rats[J].Lasers Med Sci,2008,25(1)∶25-31
[7]周骢,伍宝琴,朱中焰,等.正畸移动大鼠牙过程牙周组织中PLAP-1、BMP-2的表达及意义[J].口腔医学研究,2017,33(1)∶33-37
[8]赵鹏,金鑫,吴建刚,等.激光医学中准分子激光器能量检测的探讨[J].中国医疗设备,2014,29(5)∶131-133
[9]Shirazi M,Ahmad Akhoundi MS,Javadi E,et al.The effects of diode laser(660nm)on the rate of tooth movements:an animal study[J].Lasers Med Sci,2015,30(2)∶713-718
[10]Altan BA,Sokucu O,Ozkut MM,et al.Metrical and histological investigation of the effects of low-level laser therapy on orthodontic tooth movement[J].Lasers Med Sci,2012,27(1)∶131-140