临产孕妇凝血四项检测调查研究
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摘要
目的对临产孕妇进行凝血四项检测,观察和分析临床孕妇的凝血四项变化和凝血功能状况,研究凝血四项对于孕妇的临床意义。方法选取我院在2015年1月-2017年1月收治的800例临产孕妇和800例非妊娠妇女作为研究对象。其中800例非妊娠妇女作为对照组,800例临产妇女作为实验组,分别对其进行凝血四项检测并对两组检测结果的差别进行对比分析。结果对照组四项检测中的凝血酶时间(TT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)明显高于实验组,纤维蛋白原(FIB)明显低于实验组,差异均有统计学意义(P<0.05)。结论临产孕妇与非妊娠妇女在凝血四项中具有明显的差异,因此孕妇在临产期间的凝血四项检测对预防血液高凝等现象具有很重大的意义。
Objective Four items of blood coagulation were tested for parturient women. We analyzed four items of coagulation and coagulation function of clinical pregnant women, and studied the clinical significance of four items of coagulation for pregnant women. Methods 800 cases of parturient pregnant women and 800 non-pregnant women who were treated in our hospital from January 2015 to January 2017 were selected as the research subjects. 800 cases of non-pregnant women as control group, 800 cases of parturient women as experimental group, four coagulation tests were carried out, and the difference between two groups was compared. Results The thrombin time(TT), prothrombin time(PT), activated partial thromboplastin time(APTT) of patients in the control group were significantly higher than those in the experimental group, while fibrinogen(FIB) was significantly lower than that in the experimental group, and the differences were statistically significant(P<0.05). Conclusion Pregnant women and non pregnant women have significant differences in the four items of blood coagulation. Therefore, four tests of pregnant women's blood coagulation during labor are of great significance for preventing blood hypercoagulability.
Objective Four items of blood coagulation were tested for parturient women. We analyzed four items of coagulation and coagulation function of clinical pregnant women, and studied the clinical significance of four items of coagulation for pregnant women. Methods 800 cases of parturient pregnant women and 800 non-pregnant women who were treated in our hospital from January 2015 to January 2017 were selected as the research subjects. 800 cases of non-pregnant women as control group, 800 cases of parturient women as experimental group, four coagulation tests were carried out, and the difference between two groups was compared. Results The thrombin time(TT), prothrombin time(PT), activated partial thromboplastin time(APTT) of patients in the control group were significantly higher than those in the experimental group, while fibrinogen(FIB) was significantly lower than that in the experimental group, and the differences were statistically significant(P<0.05). Conclusion Pregnant women and non pregnant women have significant differences in the four items of blood coagulation. Therefore, four tests of pregnant women's blood coagulation during labor are of great significance for preventing blood hypercoagulability.
引文
[1]张长虹.临产孕妇凝血四项指标检测的临床分析[J].中国社区医师,2017,33(23):118,120.
[2]霍小琴.临产孕妇凝血四项及血常规检测的临床价值分析[J].基层医学论坛,2016,20(3):349-350.
[3]蔡琴.临产孕妇凝血四项检测的临床意义[J].实验与检验医学,2014,32(4):463-464.
[4]胡志愿,郭璐娣,刘俊峰,等.临产孕妇凝血四项及血常规检测的临床意义[J].现代医院,2013,13(1):46-48.
[5]凌晓午,安邦权,黄盛文,等.1,154例临产孕妇凝血四项检测调查研究[J].中国妇幼保健,2012,27(34):5553-5555.
[6]何周瑜.D-二聚体与凝血四项联合检测对临产孕妇的临床意义[J].吉林医学,2012,33(28):6102-6103.
[7]Kjellberg U,van Rooijen M,Bremme K,et al.Increased activation of blood coagulation in pregnant women with the factor V leiden mutation[J].Thromb Res,2014,134(4):837-845.
[8]Shakhbazov SG.The changes of the main indices of the blood coagulation system in pregnant women with thrombotic complications[J].Klin Khir,2009(4):47-50.
[9]Savelieva GM,Efimov VS,Grishin VL,et al.Blood coagulation changes in pregnant women at risk of developing preeclampsia[J].Int J Gynaecol Obstet,1995,48(1):3-8.
[2]霍小琴.临产孕妇凝血四项及血常规检测的临床价值分析[J].基层医学论坛,2016,20(3):349-350.
[3]蔡琴.临产孕妇凝血四项检测的临床意义[J].实验与检验医学,2014,32(4):463-464.
[4]胡志愿,郭璐娣,刘俊峰,等.临产孕妇凝血四项及血常规检测的临床意义[J].现代医院,2013,13(1):46-48.
[5]凌晓午,安邦权,黄盛文,等.1,154例临产孕妇凝血四项检测调查研究[J].中国妇幼保健,2012,27(34):5553-5555.
[6]何周瑜.D-二聚体与凝血四项联合检测对临产孕妇的临床意义[J].吉林医学,2012,33(28):6102-6103.
[7]Kjellberg U,van Rooijen M,Bremme K,et al.Increased activation of blood coagulation in pregnant women with the factor V leiden mutation[J].Thromb Res,2014,134(4):837-845.
[8]Shakhbazov SG.The changes of the main indices of the blood coagulation system in pregnant women with thrombotic complications[J].Klin Khir,2009(4):47-50.
[9]Savelieva GM,Efimov VS,Grishin VL,et al.Blood coagulation changes in pregnant women at risk of developing preeclampsia[J].Int J Gynaecol Obstet,1995,48(1):3-8.