植物中介体及其在非生物胁迫调控中的功能研究综述
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摘要
中介体复合物(Mediator Complex)是多蛋白复合物,在真核生物的转录装置中发挥着重要作用。中介体可参与调控植物的生长发育以及对非生物胁迫的响应。本文概述了中介体复合物的结构、命名方式和在转录调控中的功能,以及中介体参与植物对干旱、高盐、低温和渗透胁迫等环境下响应。
Mediator Complex is a polyprotein complex,which plays an important role in eukaryotic transcription devices. Mediators are involved in regulating plant growth and development and in response to abiotic stresses. This paper summarizes the mediator's structure,nomenclature and functions in transcriptional regulation,and its participation in plant response to drought,high salinity,low temperature and osmotic stress.
Mediator Complex is a polyprotein complex,which plays an important role in eukaryotic transcription devices. Mediators are involved in regulating plant growth and development and in response to abiotic stresses. This paper summarizes the mediator's structure,nomenclature and functions in transcriptional regulation,and its participation in plant response to drought,high salinity,low temperature and osmotic stress.
引文
[1] G GILL,M PTASHNE. Negative effect of the transcriptional activator GAL4[J]. Nature,1988,334(6184):721-724.
[2] R J KELLEHER, P M FLANAGAN, ARD KORNBERG. A novel mediator between activator proteins and the RNA polymerase II transcription apparatus[J]. Cell,1990,61(7):1209-1215.
[3] NILS ELFVING,C魪LINE DAVOINE,REYES BENLLOCH, et al. The Arabidopsis thaliana Med25 mediator subunit integrates environmental cues to control plant development.[J].PNAS,2011,108(20):8245-8250.
[4] BACKSTROM S,ELFVING N,NILSSON R,et al. Purification of a plant mediator from Arabidopsis thaliana identifies PFT1 as the Med25subunit[J]. Mol. Cell, 2007, 26(5), 717-729.
[5] H M BOURBON, A AGUILERA, A Z ANSARI, et al. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II[J]. Molecular Cell,2004,14(5):553-557.
[6] J M PARK,H S KIM,S J HAN,et al. In vivo requirement of activator-specific binding targets of mediator[J]. Molecular&Cellular Biology,2000,20(23):8709-8019.
[7] N YUDKOVSKY, J A RANISH, S HAHN.A transcription reinitiation intermediate that is stabilized by activator[J]. Nature,2000,408(6809):225-229.
[8] S BJ魻RKLUND, C M GUSTAFSSON. The yeast Mediator complex and its regulation[J].Trends in Biochemical Sciences, 2005, 30(5):240-244.
[9] S AKOULITCHEV,S CHUIKOV,D REINBERG. TFIIH is negatively regulated by cdk8-containing mediator complexes[J]. Nature,2000,407(6800):102-106.
[10] GILLMOR C S,PARK M Y,SMITH M R,et al. The MED12-MED13 module of Mediator regulates the timing of embryo patterning in Arabidopsis[J]. Development,2010,137(1):113-122.
[11] AUTRAN D,JONAK C,BELCRAM K,et al. Cell numbers and leaf development in Arabidopsis:a functional analysis of the STRUWWELPETER gene[J]. EMBO J.,2002;21(22):6036-6049.
[12] KIDD B N,EDGAR C I,KUMAR K K,et al. The Mediator complex subunit PFT1 is a key regulator of jasmonate-dependent defense in Arabidopsis[J]. Plant Cell,2009,21(8):2237-2252.
[13] SUNDARAVELPANDIAN,KALAIPANDIAN,CHANDRIKA, et al. PFT1, a transcriptional Mediator complex subunit, controls root hair differentiation through reactive oxygen species(ROS)distribution in Arabidopsis[J]. New Phytol.,2012,197(1):151-161.
[14] THAKUR J K, AGARWAL P,PARIDA S,et al. Sequence and expression analyses of KIX domain proteins suggest their importance in seed development and determination of seed size in rice, and genome stability in Arabidopsis[J]. Mol. Genet. Genomics:MGG,2013,288(7):329-346.
[15] DEEPTHI L WATHUGALA,SHANE A RICHARDS,HEATHER KNIGHT,et al. OsSFR6 is a functional rice orthologue of sensitive to freezing-6 and can act as a regulator of COR gene expression, osmotic stress and freezing tolerance in Arabidopsis[J]. New Phytol,2011,191(4):984-995.
[16] P D CERD魣N, J CHORY. Regulation of flowering time by light quality[J]. Nature,2003,423(6942):881-885.
[17] LI XIAOHUI, YANG RUI, GONG YIFU,et al. The Arabidopsis Mediator complex subunit MED19a is involved in ABI5-mediated ABA responses[J]. Journal of Plant Biology,2018, 61(2):97-110.
[18] SALONI MATHUR,SHAILENDRA VYAS,SANJAY KAPOOR,et al. The Mediator complex in plants:Structure, phylogeny, and expression profiling of representative genes in a dicot(Arabidopsis)and a monocot(rice)during reproduction and abiotic stress[J].Plant physiology,2011,157(4):1609-1627.
[19]魏荷,李海朝,练云,等.大豆中介体亚基基因鉴定及表达特性分析[J].大豆科学,2016,35(1):31-38.
[20]王晶,赵军,宗娜.玉米中介体亚基ZmMED7基因的克隆及表达分析[J].生物技术进展,2016,6(5):328-335.
[21] KNIGHT H, MUGFORD NEE GARTON S G,ULKER B,et al. Identification of SFR6,a key component in cold acclimation acting post-translationally on CBF function[J]. The Plant Journal,2009,58(1):97-108.
[22] HEMSLEY P A,HURST C H, KALIYADASA E,et al. The Arabidopsis Mediator complex subunits MED16, MED14, and MED2regulate mediator and RNA polymerase II recruitment to CBF-responsive cold-regulated genes[J]. The Plant Cell,2014(1),26:465-484.
[23] YAN YANG, BIN OU, JINZHE ZHANG.The Arabidopsis Mediator subunit MED 16regulates iron homeostasis by associating with EIN 3/EIL 1 through subunit MED 25[J].The Plant journal,2014,77(6):838-851.
[24] BOYCE J M,KNIGHT H,DEYHOLOS M,et al. The sfr6 mutant of Arabidopsis is defective in transcriptional activation via CBF/DREB1 and DREB2 and shows sensitivity to osmotic stress[J]. The Plant Journal,2003,34(4):395-406.
[25] QIN F, SHINOZAKI K,YAMAGUCHI S K.Achievements and challenges in understanding plant abiotic stress responses and tolerance[J]. Plant Cell Physiol,2011,52(9):1569-1582.
[2] R J KELLEHER, P M FLANAGAN, ARD KORNBERG. A novel mediator between activator proteins and the RNA polymerase II transcription apparatus[J]. Cell,1990,61(7):1209-1215.
[3] NILS ELFVING,C魪LINE DAVOINE,REYES BENLLOCH, et al. The Arabidopsis thaliana Med25 mediator subunit integrates environmental cues to control plant development.[J].PNAS,2011,108(20):8245-8250.
[4] BACKSTROM S,ELFVING N,NILSSON R,et al. Purification of a plant mediator from Arabidopsis thaliana identifies PFT1 as the Med25subunit[J]. Mol. Cell, 2007, 26(5), 717-729.
[5] H M BOURBON, A AGUILERA, A Z ANSARI, et al. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II[J]. Molecular Cell,2004,14(5):553-557.
[6] J M PARK,H S KIM,S J HAN,et al. In vivo requirement of activator-specific binding targets of mediator[J]. Molecular&Cellular Biology,2000,20(23):8709-8019.
[7] N YUDKOVSKY, J A RANISH, S HAHN.A transcription reinitiation intermediate that is stabilized by activator[J]. Nature,2000,408(6809):225-229.
[8] S BJ魻RKLUND, C M GUSTAFSSON. The yeast Mediator complex and its regulation[J].Trends in Biochemical Sciences, 2005, 30(5):240-244.
[9] S AKOULITCHEV,S CHUIKOV,D REINBERG. TFIIH is negatively regulated by cdk8-containing mediator complexes[J]. Nature,2000,407(6800):102-106.
[10] GILLMOR C S,PARK M Y,SMITH M R,et al. The MED12-MED13 module of Mediator regulates the timing of embryo patterning in Arabidopsis[J]. Development,2010,137(1):113-122.
[11] AUTRAN D,JONAK C,BELCRAM K,et al. Cell numbers and leaf development in Arabidopsis:a functional analysis of the STRUWWELPETER gene[J]. EMBO J.,2002;21(22):6036-6049.
[12] KIDD B N,EDGAR C I,KUMAR K K,et al. The Mediator complex subunit PFT1 is a key regulator of jasmonate-dependent defense in Arabidopsis[J]. Plant Cell,2009,21(8):2237-2252.
[13] SUNDARAVELPANDIAN,KALAIPANDIAN,CHANDRIKA, et al. PFT1, a transcriptional Mediator complex subunit, controls root hair differentiation through reactive oxygen species(ROS)distribution in Arabidopsis[J]. New Phytol.,2012,197(1):151-161.
[14] THAKUR J K, AGARWAL P,PARIDA S,et al. Sequence and expression analyses of KIX domain proteins suggest their importance in seed development and determination of seed size in rice, and genome stability in Arabidopsis[J]. Mol. Genet. Genomics:MGG,2013,288(7):329-346.
[15] DEEPTHI L WATHUGALA,SHANE A RICHARDS,HEATHER KNIGHT,et al. OsSFR6 is a functional rice orthologue of sensitive to freezing-6 and can act as a regulator of COR gene expression, osmotic stress and freezing tolerance in Arabidopsis[J]. New Phytol,2011,191(4):984-995.
[16] P D CERD魣N, J CHORY. Regulation of flowering time by light quality[J]. Nature,2003,423(6942):881-885.
[17] LI XIAOHUI, YANG RUI, GONG YIFU,et al. The Arabidopsis Mediator complex subunit MED19a is involved in ABI5-mediated ABA responses[J]. Journal of Plant Biology,2018, 61(2):97-110.
[18] SALONI MATHUR,SHAILENDRA VYAS,SANJAY KAPOOR,et al. The Mediator complex in plants:Structure, phylogeny, and expression profiling of representative genes in a dicot(Arabidopsis)and a monocot(rice)during reproduction and abiotic stress[J].Plant physiology,2011,157(4):1609-1627.
[19]魏荷,李海朝,练云,等.大豆中介体亚基基因鉴定及表达特性分析[J].大豆科学,2016,35(1):31-38.
[20]王晶,赵军,宗娜.玉米中介体亚基ZmMED7基因的克隆及表达分析[J].生物技术进展,2016,6(5):328-335.
[21] KNIGHT H, MUGFORD NEE GARTON S G,ULKER B,et al. Identification of SFR6,a key component in cold acclimation acting post-translationally on CBF function[J]. The Plant Journal,2009,58(1):97-108.
[22] HEMSLEY P A,HURST C H, KALIYADASA E,et al. The Arabidopsis Mediator complex subunits MED16, MED14, and MED2regulate mediator and RNA polymerase II recruitment to CBF-responsive cold-regulated genes[J]. The Plant Cell,2014(1),26:465-484.
[23] YAN YANG, BIN OU, JINZHE ZHANG.The Arabidopsis Mediator subunit MED 16regulates iron homeostasis by associating with EIN 3/EIL 1 through subunit MED 25[J].The Plant journal,2014,77(6):838-851.
[24] BOYCE J M,KNIGHT H,DEYHOLOS M,et al. The sfr6 mutant of Arabidopsis is defective in transcriptional activation via CBF/DREB1 and DREB2 and shows sensitivity to osmotic stress[J]. The Plant Journal,2003,34(4):395-406.
[25] QIN F, SHINOZAKI K,YAMAGUCHI S K.Achievements and challenges in understanding plant abiotic stress responses and tolerance[J]. Plant Cell Physiol,2011,52(9):1569-1582.