MRI对高级别胶质瘤与原发性中枢神经淋巴瘤的诊断鉴别作用
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摘要
目的探讨MRI对高级别胶质瘤与原发性中枢神经淋巴瘤的诊断鉴别作用。方法选取25例经病理证实的高级别胶质瘤与28例原发性中枢神经淋巴瘤为研究对象,所有患者均接受MRI检查,对两种疾病的MRI表现进行对比观察。结果高级别胶质瘤与原发性中枢神经淋巴瘤在DWI信号、囊变坏死、增强形态、肿瘤内血管评分、病灶ADC值、rADC值等方面存在明显差异(P <0.05)。结论高级别胶质瘤与原发性中枢神经淋巴瘤可通过MRI特征进行鉴别,为临床早期治疗提供参考依据。
Objective To explore the differential diagnosis of high-grade glioma and primary central neurolymphoma by MRI. Methods Twenty-five cases of high-grade glioma confirmed by pathology and 28 cases of primary central neuro-lymphoma were selected as subjects. All patients underwent MRI.MRI findings of both diseases were observed. Results There were significant differences in DWI signal,cystic necrosis,enhanced morphology,intratumoral vascular score,lesion ADC value and rADC value between high-grade glioma and primary central neurolymphoma(P<0.05). Conclusion High-grade gliomas and primary central neuro-lymphomas can be identified by MRI features,providing a reference for early clinical treatment.
Objective To explore the differential diagnosis of high-grade glioma and primary central neurolymphoma by MRI. Methods Twenty-five cases of high-grade glioma confirmed by pathology and 28 cases of primary central neuro-lymphoma were selected as subjects. All patients underwent MRI.MRI findings of both diseases were observed. Results There were significant differences in DWI signal,cystic necrosis,enhanced morphology,intratumoral vascular score,lesion ADC value and rADC value between high-grade glioma and primary central neurolymphoma(P<0.05). Conclusion High-grade gliomas and primary central neuro-lymphomas can be identified by MRI features,providing a reference for early clinical treatment.
引文
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[8]张颖,牛广明,韩晓东,等.磁共振灌注成像对脑内占位性病变鉴别诊断的价值[J].内蒙古医科大学学报,2016,58(1):25-29,34.
[2]王旭华.对原发性中枢神经系统淋巴瘤影像学特点的分析[J].当代医药论丛,2016,14(8):34-35.
[3]耿磊,孙毅,孙志先,等.MRI鉴别诊断原发性中枢神经系统淋巴瘤与高级别胶质瘤深部病灶[J].中国介入影像与治疗学,2018,15(2):95-99.
[4]吴敏,赵红光,关锋,等.18F-FDG PET/CT显像在原发性中枢神经系统淋巴瘤诊断中的应用[J].吉林大学学报(医学版),2015,41(2):401-404.
[5]景治涛,崔启韬,李连翔,等.原发性中枢神经系统淋巴瘤CT、MRI表现及临床病理特征[J].陕西医学杂志,2016,45(6):690-692.
[6]曹中华,谭得力,高锋,等.SWI对脑淋巴瘤及高级别胶质瘤的鉴别诊断价值[J].中国CT和MRI杂志,2017,15(11):28-30.
[7]王海莉,张中冕.原发性中枢神经系统淋巴瘤临床表现、影像学特征及病理诊断分析[J].中国实验血液学杂志,2018,26(1):171-176.
[8]张颖,牛广明,韩晓东,等.磁共振灌注成像对脑内占位性病变鉴别诊断的价值[J].内蒙古医科大学学报,2016,58(1):25-29,34.