重金属对水生生物的生态毒理效应及生物耐受机制研究进展
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摘要
近年来,随着国民经济的快速发展,重金属以其特有的性质而被大量的应用于生产生活当中,同时也由于各种原因造成了水体重金属污染现象。水体重金属污染不仅对水生生物的生长和繁殖造成了严重的威胁,同时也威胁到人类的健康。因此,重金属污染具有潜在的生态与健康风险。本文主要概括介绍了重金属对水生植物、动物、微生物的生态毒理效应以及水生生物对重金属的各种耐受机制,展望了重金属对水生生物生态毒理效应的未来研究重点和方向。
With the rapid development of economy,heavy metals have been widely used in industry and life due to their unique properties. This also results in seriously environmental pollution. The heavy metal pollution in water is a serious threat not only to the growth and reproduction of aquatic organisms,but also to human health. Therefore,heavy metal pollution possess the potential risk of ecological and health. In this paper,the ecotoxicological effect of heavy metals on aquatic plants,animals and microorganisms,and the tolerance mechanisms of aquatic organisms to heavy metals are reviewed. In addition,the research emphasis and direction of aquatic ecological toxicity effects of heavy metals were also discussed.
With the rapid development of economy,heavy metals have been widely used in industry and life due to their unique properties. This also results in seriously environmental pollution. The heavy metal pollution in water is a serious threat not only to the growth and reproduction of aquatic organisms,but also to human health. Therefore,heavy metal pollution possess the potential risk of ecological and health. In this paper,the ecotoxicological effect of heavy metals on aquatic plants,animals and microorganisms,and the tolerance mechanisms of aquatic organisms to heavy metals are reviewed. In addition,the research emphasis and direction of aquatic ecological toxicity effects of heavy metals were also discussed.
引文
[1]Yuan G L,Liu C,Chen L,et al.Inputting history of heavy metals into the inland lake recorded in sediment profiles:Poyang Lake in China[J].Journal of Hazardous Materials,2011,185(1):336-345
[2]Fernandes A R,Mortimer D N,Rose M,et al.Occurrence of dioxins(PCDDs,PCDFs)and polychlorinated biphenyls(PCBs)in wild,farmed and processed fish,and shellfish[J].Food Additives&Contaminants Part B Surveillance,2009,2(1):15-20
[3]Rose M,Fernandes A,Mortimer D,et al.Contamination of fish in UK fresh water systems:Risk assessment for human consumption[J].Chemosphere,2015,122(10):183-189
[4]Sfakianakis D G,Renieri E,Kentouri M,et al.Effect of heavy metals on fish larvae deformities:A review[J].Environmental Research,2015,137:246-255
[5]Valko M,Morris H,Cronin M T.Metals,toxicity and oxidative stress[J].Current Medicinal Chemistry,2005,12(10):1161-1208
[6]Islam M S,Tanaka M.Impacts of pollution on coastal and marine ecosystems including coastal and marine fisheries and approach for management:A review and synthesis[J].Systematic Biology,2004,48(7-8):624-649
[7]Mohanty D,Samanta L.Multivariate analysis of potential biomarkers of oxidative stress in Notopterus notopterus tissues from Mahanadi River as a function of concentration of heavy metals[J].Chemosphere,2016,155:28-38
[8]韦丽丽,周琼,谢从新,等.三峡库区重金属的生物富集、生物放大及其生物因子的影响[J].环境科学,2016,37(1):325-334Wei L L,Zhou Q,Xie C X,et al.Bioaccumulation and biomagnification of heavy metal in Three Gorges Reservoir and effect of biological factors[J].Envioronmentd Science,2016,37(1):325-334(in Chinese)
[9]王宏镔,束文圣,蓝崇钰.重金属污染生态学研究现状与展望[J].生态学报,2005,25(3):596-605Wang H B,Shu W S,Lan C Y.Ecology for heavy metal pollution:Recent advances and future prospects[J].Acta Ecologica Sinica,2005,25(3):596-605(in Chinese)
[10]Mann R M,Hyne R V,Choung C B,et al.Amphibians and agricultural chemicals:Review of the risks in a complex environment[J].Environmental Pollution,2009,157(11):2903-2927
[11]刘健康.高级水生生物学[M].北京:科学出版社,1999:224-225Liu J K.Advanced Aquatic Biology[M].Beijing:Science Press,1999:224-225(in Chinese)
[12]张义贤.重金属对大麦(Hordeum vulgare)毒性的研究[J].环境科学学报,1997(2):199-205Zhang Y X.Toxicity of heavy metals to Hordeum vulgare[J].Acta Scientiae Circumstantiae,1997(2):199-205(Chinese)
[13]胡金朝.重金属污染对不同生境水生植物的毒害机理研究[D].南京:南京师范大学,2006:10-21Hu J Z.The toxic mechanism study of heavy metal pollution on aquatic plant under different growth conditions[D].Nanjing:Nanjing Normal University,2006:10-21(in Chinese)
[14]Zhang W,Tan N G J,Fu B,et al.Metallomics and NMR-based metabolomics of Chlorella sp.reveal the synergistic role of copper and cadmium in multi-metal toxicity and oxidative stress[J].Metallomics,2015,7(3):426-438
[15]Prado C,Rodríguez-Montelongo L,González J A,et al.Uptake of chromium by Salvinia minima:Effect on plant growth,leaf respiration and carbohydrate metabolism[J].Journal of Hazardous Materials,2010,177(1-3):546-553
[16]Vesel'y T,SzákováP T J.The use of water lettuce(Pistia stratiotes L.)for rhizofiltration of a highly polluted solution by cadmium and lead[J].International Journal of Phytoremediation,2011,13(9):859-872
[17]涂俊芳,储昭霞,欧智涛,等.Zn/Pb与Cr单一胁迫下青萍的生长状况及其富集能力[J].生物学杂志,2015,32(4):38-42Tu J F,Chu Z X,Ou Z T,et al.Growth and bioaccumulation of Lemna minor exposed to Zn,Pb and Cr[J].Journal of Biology,2015,32(4):38-42(in Chinese)
[18]Malar S,Sahi S V,Favas P J C,et al.Mercury heavymetal-induced physiochemical changes and genotoxic alterations in water hyacinths[Eichhornia crassipes,(Mart.)][J].Environmental Science&Pollution Research,2015,22(6):4597-4608
[19]Samardakiewicz S,Wozny A.Cell division in Lemna minor roots treated with lead[J].Aquatic Botany,2005,83(3):289-295
[20]Basile A,Sorbo S,Cardi M,et al.Effects of heavy metals on ultrastructure and Hsp70 induction in Lemna minor L.exposed to water along the Sarno River,Italy[J].Ecotoxicology and Environmental Safety,2015,114:93-101
[21]Zhang W,Tan N G,Fu B,et al.Metallomics and NMR-based metabolomics of Chlorella sp.reveal the synergistic role of copper and cadmium in multi-metal toxicity and oxidative stress[J].Metallomics Integrated Biometal Science,2015,7(3):426-438
[22]Gupta M,Sarin N B.Heavy metal induced DNA changes in aquatic macrophytes:Random amplified polymorphic DNA analysis and identification of sequence characterized amplified region marker[J].Journal of Environmental Sciences,2009,21(5):686-690
[23]陈雷,郑青松,刘兆普,等.不同Cu2+浓度处理对斜生栅藻生长及叶绿素荧光特性的影响[J].生态环境学报,2009,18(4):1231-1235Chen L,Zheng Q S,Liu Z P,et al.Effects of different concentrations of copper ion on the growth and chlorophyll fluorescence characteristics of Scendesmus obliquus[J].Ecology and Environment,2009,18(4):1231-1235(in Chinese)
[24]简敏菲,汪斯琛,余厚平,等.Cd2+、Cu2+胁迫对黑藻(Hydrilla verticillata)的生长及光合荧光特性的影响[J].生态学报,2016,36(6):1719-1727Jian M F,Wang S C,Yu H P,et al.Influence of Cd2+or Cu2+stress on the growth and photosynthetic fluorescence characteristics of Hydrilla verticillata[J].Acta Ecologica Sinica,2016,36(6):1719-1727(in Chinese)
[25]樊香绒,尹黎燕,李伟,等.不同价态砷对斜生栅藻生长及叶绿素荧光的影响[J].水生态学杂志,2013,34(5):60-64Fan X R,Yin L Y,Li W,et al.Effect of arsenic species on the growth and chlorophyll fluorescence characteristics of Scenedesmus obliquus[J].Journal of Hydroecology,2013,34(5):60-64(in Chinese)
[26]Deng G,Li M,Li H,et al.Exposure to cadmium causes declines in growth and photosynthesis in the endangered aquatic fern(Ceratopteris pteridoides)[J].A-quatic Botany,2014,112(112):23-32
[27]潘义宏,王宏镔,谷兆萍,等.大型水生植物对重金属的富集与转移[J].生态学报,2010,30(23):6430-6441Pan Y H,Wang H B,Gu Z P,et al.Accumulation and translocation of heavy metals by macrophytes[J].Acta Ecologica Sinica,2010,30(23):6430-6441(in Chinese)
[28]Rezania R,Taib S M,Din M F M,et al.Comprehensive review on phytotechnology:Heavy metals removal by diverse aquatic plants species from wastewater[J].Journal of Hazardous Materials,2016,318:587-599
[29]Solanki R,Dhankhar R.Biochemical changes and adaptive strategies of plants under heavy metal stress[J].Biologia,2011,66(66):195-204
[30]Hall J L.Cellular mechanisms for heavy metal detoxification and tolerance[J].Journal of Experimental Botany,2002,53(366):1-11
[31]Piotrowska A,Bajguz A,Godlewska-Z·ykiewicz B,et al.Changes in growth,biochemical components,and antioxidant activity in aquatic plant Wolffia arrhiza(Lemnaceae)exposed to cadmium and lead[J].Archives of Environmental Contamination&Toxicology,2010,58(3):594-604
[32]Morel J L,Mench M,Guckert A.Measurement of Pb2+,Cu2+and Cd2+binding with mucilage exudates from maize(Zea mays L.)roots[J].Biology&Fertility of Soils,1986,2(1):29-34
[33]Xin W,Liu Y G,Zeng G M,et al.Subcellular distribution and chemical forms of cadmium in Bechmeria nivea(L.)Gaud[J].Environmental&Experimental Botany,2008,62(3):389-395
[34]Monteiro C M,Castro P M L,Malcata F X.Metal uptake by microalgae:Underlying mechanisms and practical applications[J].Biotechnology Progress,2012,28(2):299-311
[35]Kramer U.Cadmium for all meals-plants with an unusual appetite[J].New Phytologist,2000,145(1):1-3
[36]Oveˇc ka M,Takáˇc T.Managing heavy metal toxicity stress in plants:Biological and biotechnological tools[J].Biotechnology Advances,2014,32(1):73-86
[37]Liu Z,Gu C,Chen F,et al.Heterologous expression of a Nelumbo nucifera phytochelatin synthase gene enhances cadmium tolerance in Arabidopsis thaliana[J].Applied Biochemistry&Biotechnology,2012,166(3):722-734
[38]Xu W,Shi W,Yan F,et al.Mechanisms of cadmium detoxification in cattail(Typha angustifolia L.)[J].A-quatic Botany,2011,94(1):37-43
[39]Kumar K S,Dahms H U,Won E J,et al.Microalgae-Apromising tool for heavy metal remediation[J].Ecotoxicology&Environmental Safety,2015,113:329-352
[40]Islam E,Khan M T,Irem S.Biochemical mechanisms of signaling:Perspectives in plants under arsenic stress[J].Ecotoxicology&Environmental Safety,2015,114:126-133
[41]Haq N U,Raza S,Luthe D S,et al.A dual role for the chloroplast small heat shock protein of Chenopodium album,including protection from both heat and metal stress[J].Plant Molecular Biology Reporter,2013,31(2):398-408
[42]袁秋红.重金属对水生植物抗氧化系统的影响及重金属胁迫蛋白研究[D].南京:南京师范大学,2008:14Yuan Q H.The study on effect of antioxidant system of heavy metals on the aquatic plants and heavy metal stress protein[D].Nanjing:Nanjing Normal University,2008:14(in Chinese)
[43]Kuyucak N,Volesky B.Biosorbents for recovery of metals from industrial solutions[J].Biotechnology Letters,1988,10(2):137-142
[44]刘清泉,陈亚华,沈振国,等.细胞壁在植物重金属耐性中的作用[J].植物生理学报,2014,50(5):605-611Liu Q Q,Chen Y H,Shen Z G,et al.Roles of cell wall in plant heavy metal tolerance[J].Plant Physiology Journal,2014,50(5):605-611(in Chinese)
[45]Soldo D,Hari R,Sigg L,et al.Tolerance of Oocystis nephrocytioides to copper:Intracellular distribution and extracellular complexation of copper[J].Aquatic Toxicology,2005,71(4):307-317
[46]Nies D H,Silver S.Ion efflux systems involved in bacterial metal resistances[J].Journal of Industrial Microbiology,1995,14(2):186-199
[47]Ishaque A B,Linda J,Tonya G,et al.Assessment of individual and combined toxicities of four non-essential metals(As,Cd,Hg and Pb)in the microtox assay[J].International Journal of Environmental Research&Public Health,2006,3(1):118-120
[48]Wada S,Suziki S.Inhibitory effect of zinc on the remineralisation of dissolved organic matter in the coastal environment[J].Aquatic Microbial Ecology,2011,63(1):47-59
[49]Giller K E,Witter E,Mcgrath S P.Toxicity of heavy metals to microorganisms and microbial processes in agricultural soils:A review[J].Soil Biology&Biochemistry,1998,30(10-11):1389-1414
[50]Taylor M G,Simkiss K,Greaves G N,et al.Corrosion of intracellular granules and cell death[J].Royal Society of London Proceedings,1988,234(1277):463-476
[51]刘瑞霞,汤鸿霄,劳伟雄.重金属的生物吸附机理及吸附平衡模式研究[J].化学进展,2002,14(2):87-92Liu R X,Tang H X,Lao W X.Advances in biosorption mechanism and equilibrium modeling for heavy metals on biomaterials[J].Progress in Chemistry,2002,14(2):87-92(in Chinese)
[52]张甲耀.环境微生物学(下)[M].武汉:武汉大学出版社,2008:127-128Zhang J Y.Environmental Microbiology(2)[M].Wuhan:Wuhan University Press,2008:127-128(in Chinese)
[53]Houba C,Remacle J.Composition of the saprophytic bacterial communities in freshwater systems contaminated by heavy metals[J].Microbial Ecology,1980,6(1):55-69
[54]陈素华,孙铁珩,周启星,等.微生物与重金属间的相互作用及其应用研究[J].应用生态学报,2002,13(2):239-242Chen S H,Sun T H,Zhou Q X,et al.Interaction between microorganisms and heavy metals and its application[J].Chinese Journal of Applied Ecology,2002,13(2):239-242(in Chinese)
[55]孙晋伟,黄益宗,石孟春,等.土壤重金属生物毒性研究进展[J].生态学报,2008,28(6):2861-2869Sun J W,Huang Y Z,Shi M C,et al.The review of heavy metals biotoxicity[J].Acta Ecologica Sinica,2008,28(6):2861-2869(in Chinese)
[56]Wang C,Shan B,Zhang H,et al.Limitation of spatial distribution of ammonia-oxidizing microorganisms in the Haihe River,China,by heavy metals[J].Journal of Environmental Sciences,2014,26(3):502-511
[57]Zhou S,Wei C H,Liao C D,et al.Damage to DNA of effective microorganisms by heavy metals:Impact on wastewater treatment[J].Journal of Environmental Sciences,2008,20(12):1514-1518
[58]Ozdemir G,Ozturk T,Ceyhan N,et al.Heavy metal biosorption by biomass of Ochrobactrum anthropi producing exopolysaccharide in activated sludge[J].Bioresource Technology,2003,90(1):71-74
[59]丁为群,刘迪秋,葛锋,等.鱼类对重金属胁迫的分子反应机理[J].生物学杂志,2012,29(2):84-87Ding W Q,Liu D Q,Ge F,et al.The molecular mechanism by heavy metal stress in fish[J].Journal of Biology,2012,29(2):84-87(in Chinese)
[60]Craig A,Hare L,Tessier A.Experimental evidence for cadmium uptake via calcium channels in the aquatic insect Chironomus staegeri[J].Aquatic Toxicology,1999,44(98):255-262
[61]杜建国,赵佳懿,陈彬,等.应用物种敏感性分布评估重金属对海洋生物的生态风险[J].生态毒理学报,2013,8(4):561-570Du J G,Zhao J Y,Chen B,et al.Assessing eological risks of heavy metals to marine organisms by species sensitivity distributions[J].Asian Journal of Ecotoxicology,2013,8(4):561-570(in Chinese)
[62]Bian B,Zhou Y,Fang B B.Distribution of heavy metals and benthic macroinvertebrates:Impacts from typical inflow river sediments in the Taihu Basin,China[J].Ecological Indicators,2016,69:348-359
[63]Javed M,Usmani N.Impact of heavy metal toxicity on hematology and glycogen status of fish:A review[J].Proceedings of the National Academy of Sciences,India-Section B:Biological Sciences,2014,85(4):889-900
[64]Agrawal S J,Srivastava A K,Chaudhry H S.Haematological effects of nickel toxicity on a fresh water teleost,Colisa fasciatus[J].Acta Pharmacologica et Toxicologica,1979,45(3):215-217
[65]Tripathi S,Mishra B B,Tripathi S P.Effect of heavy metal cadmium sulphate on the toxicity and biochemical parameters of reproductive cycle of Colisa fasciatus[J].Researcher,2012,4(4):65-68
[66]Ryvolova M,Krizkova S,Adam V,et al.Analytical methods for metallothionein detection[J].Current Analytical Chemistry,2011,700(3):243-261
[67]Fatima M,Usmani N,Firdaus F,et al.In vivo induction of antioxidant response and oxidative stress associated with genotoxicity and histopathological alteration in two commercial fish species due to heavy metals exposure in northern India(Kali)river[J].Comparative Biochemistry&Physiology Part C Toxicology&Pharmacology,2015,176-177:17-30
[68]Morcillo P,Esteban M,Cuesta A.Heavy metals produce toxicity,oxidative stress and apoptosis in the marine teleost fish SAF-1 cell line.[J].Chemosphere,2015,144:225-233
[69]马京津,徐团,轩瑞晶,等.铅对河南华溪蟹卵巢抗氧化酶活力和脂质过氧化水平的影响[J].环境科学学报,2012,32(9):2346-2352Ma J J,Xu T,Xuan R J,et al.Effects of lead on ovaries lipid peroxidation level and antioxidant enzyme activity in freshwater crab Sinopotamon henanense[J].Acta Scientiae Circumstantiae,2012,32(9):2346-2352(in Chinese)
[70]Kim B M,Rhee J S,Jeong C B,et al.Heavy metals induce oxidative stress and trigger oxidative stress-mediated heat shock protein(hsp)modulation in the intertidal copepod Tigriopus japonicus[J].Comparative Biochemistry&Physiology Part C Toxicology&Pharmacology,2014,166(1):65-74
[71]殷健.重金属对斑马鱼的毒性效应及作用机制研究[D].北京:北京协和医学院,2014:53Yin J.Studies on toxic effect and mechanism of heavy metals on zebrafish[D].Beijing:Peking Union Medical College,2014:53(in Chinese)
[72]Morcillo P,Cordero H,Meseguer J,et al.Toxicological in vitro effects of heavy metals on gilthead seabream(Sparus aurata L.)head-kidney leucocytes[J].Toxicology in Vitro,2015,30(1):412-420
[73]Handy R D.Chronic effects of copper exposure versus endocrine toxicity:Two sides of the same toxicological process?[J].Comparative Biochemistry&Physiology Part A Molecular&Integrative Physiology,2003,135(1):25-38
[74]韩雨薇,张彦峰,陈萌,等.沉积物中重金属Pb和Cd对河蚬的毒性效应研究[J].生态毒理学报,2015,10(4):129-137Han Y W,Zhang Y F,Chen M,et al.Toxicity of Pb,Cd-spiked freshwater sediments to Corbicula fluminea[J].Asian Journal of Ecotoxicology,2015,10(4):129-137(in Chinese)
[75]沈洪艳,曹志会,张红燕,等.淡水沉积物中Cd和Cu对河蚬的毒性效应研究[J].中国环境科学,2016,36(1):286-292Shen H Y,Cao Z H,Zhang H Y,et al.The toxic effects of Cd and Cu in freshwater sediments on Corbicula fluminea[J].China Environmental Science,2016,36(1):286-292(in Chinese)
[76]Morcillo P,Cordero H,Meseguer J,et al.In vitro immunotoxicological effects of heavy metals on European sea bass(Dicentrarchus labrax L.)head-kidney leucocytes.[J].Fish&Shellfish Immunology,2015,47(1):245-254
[77]Witeska M,Sarnowski P,ugowska K,et al.The effects of cadmium and copper on embryonic and larval development of ide Leuciscus idus L.[J].Fish Physiology&Biochemistry,2013,40(1):151-163
[78]穆景利,王莹,王新红,等.Cd2+、Hg2+、Cr6+和Pb2+对黑点青鳉(Oryzias melastigma)早期生活阶段的毒性效应研究[J].生态毒理学报,2011,6(4):352-360Mu J,Wang Y,Wang X,et al.Toxic effects of cadmium,mercury,chromium and lead on the early life stage of marine medaka(Oryzias melastigma)[J].Asian Journal of Ecotoxicology,2011,6(4):352-360(in Chinese)
[79]Jezierska B,ugowska K,Witeska M.The effects of heavy metals on embryonic development of fish(a review)[J].Fish Physiology and Biochemistry,2009,35(4):625-640
[80]孙翰昌,徐敬明,甘桂云.4种重金属对禾花鱼胚胎的毒性效应[J].水生态学杂志,2013,34(1):92-95Sun H C,Xu J M,Gan G Y.Toxicity effects of four heavy metals on the embryo of Procypris merus[J].Journal of Hydroecology,2013,34(1):92-95(in Chinese)
[81]章强,辛琦,强丽媛,等.铜及其与四环素的联合暴露对斑马鱼胚胎的毒性效应[J].生态毒理学报,2015,10(5):35-46Zhang Q,Xin Q,Qiang L Y,et al.Developmental toxicity of Cu and tetracycline on zebrafish embryos(Danio rerio)[J].Asian Journal of Ecotoxicology,2015,10(5):35-46(in Chinese)
[82]Kessabi K,Kerkeni A,Sa6d K,et al.Involvement of Cd bioaccumulation in spinal deformities occurrence in natural populations of mediterranean killifish[J].Biological Trace Element Research,2008,128(1):72-81
[83]Lourduraj A V,Azhagu M,Peranandam R,et al.The application of histocytopathological biomarkers in the mud crab Scylla serrata(Forskal)to assess heavy metal toxicity in Pulicat Lake,Chennai[J].Marine Pollution Bulletin,2014,81(1):85-93
[84]Kong X,Jiang H,Wang S,et al.Effects of copper exposure on the hatching status and antioxidant defense at different developmental stages of embryos and larvae of goldfish Carassius auratus[J].Chemosphere,2013,92(11):1458-1464
[85]Barjhoux I,Baudrimont M,Morin B,et al.Effects of copper and cadmium spiked-sediments on embryonic development of Japanese medaka(Oryzias latipes)[J].Ecotoxicology&Environmental Safety,2012,79(79):272-282
[86]张迎梅,王叶菁,虞闰六,等.重金属Cd2+、Pb2+和Zn2+对泥鳅DNA损伤的研究[J].水生生物学报,2006,30(4):399-403Zhang Y M,Wang Y J,Yu R L,et al.Effects of heavy metals Cd2+,Pb2+and Zn2+on and damage of loach Misgurnus anguillicandatus[J].Acta Hydrobiologica Sinica,2006,30(4):399-403(in Chinese)
[87]Ahmed M K,Kundu G K,Al-Mamun M H,et al.Chromium(VI)induced acute toxicity and genotoxicity in freshwater stinging catfish,Heteropneustes fossilis[J].Ecotoxicology&Environmental Safety,2013,92(3):64-70
[88]张德莉,朱圣姬,罗光富,等.自由基与DNA氧化损伤的研究进展[J].三峡大学学报:自然科学版,2004,26(6):563-567Zhang D L,Zhu S J,Luo G F,et al.Development of free radical-induced oxidative damage to DNA[J].Journal of China Three Gores University:Natural Sciences,2004,26(6):563-567(in Chinese)
[89]韩照祥,许兴友,谢惠珠.重金属与鲑鱼精DNA作用的比较研究[J].农业环境科学学报,2007,26(1):164-169Han Z X,Xu X Y,Xie H Z.Interaction between heavy metals and the DNA from salmon sperm[J].Journal of Agro-environment Science,2007,26(1):164-169(in Chinese)
[90]Bandyopadhyay A.Sensitivity of Allium and Nicotiana in cellular and acellular comet assays to assess differential genotoxicity of direct and indirect acting mutagens[J].Ecotoxicology&Environmental Safety,2011,74(4):860-865
[91]Giaginis C,Gatzidou E,Theocharis S.DNA repair systems as targets of cadmium toxicity[J].Toxicology&Applied Pharmacology,2006,213(3):282-290
[92]Dai W,Fu L,Du H,et al.Effects of montmorillonite on Pb accumulation,oxidative stress,and DNA damage in tilapia(Oreochromis niloticus)exposed to dietary Pb[J].Biological Trace Element Research,2010,136(1):71-78
[93]郭勇勇,华江环,杨丽华,等.三峡库区水样中重金属含量及其对斑马鱼胚胎发育的毒性评价[J].水生生物学报,2015,39(5):885-892Guo Y Y,Hua J H,Yang L H,et al.Analysis of heavy metals in the surface water from the Three Gorges Reservoir and its toxic effects on the embryonic development of the zebrafish[J].Acta Hydrobiologica Sinica,2015,39(5):885-892(in Chinese)
[94]Vandegehuchte M B,Vandenbrouck T,Coninck D D,et al.Gene transcription and higher-level effects of multigenerational Zn exposure in Daphnia magna[J].Chemosphere,2010,80(9):1014-1020
[95]盛樟,竺俊全.水生动物金属硫蛋白分子毒理学研究进展[J].生物学杂志,2014,31(2):77-81Sheng Z,Zhu J Q.Research progress on molecular toxicology of metallothionein in aquatic animals[J].Journal of Biology,2014,31(2):77-81(in Chinese)
[96]Mao H,Tan F Q,Wang D H,et al.Expression and function analysis of metallothionein in the testis of stone crab Charybdis japonica exposed to cadmium[J].A-quatic Toxicology,2012,124-125(12):11-21
[97]Liu J,Ma L,Yin S,et al.Effects of Ce3+on conformation and activity of superoxide dismutase[J].Biological Trace Element Research,2008,125(2):170-178
[98]Rhee J S,Kim B M,Jeong C B,et al.Development of enzyme-linked immunosorbent assay(ELISA)for glutathione S-transferase(GST-S)protein in the intertidal copepod Tigriopus japonicus and its application for environmental monitoring[J].Chemosphere,2013,93(10):2458-2466
[99]孙元敏,马志远,黄海萍.我国海岛潮间带贝类体中重金属含量及其评价[J].中国环境科学,2015,35(2):574-578Sun Y M,Ma Z Y,Huang H P.Contamination and assessment of heavy metals shellfish in the intertidal zone of sea islands in China[J].China Environmental Science,2015,35(2):574-578(in Chinese)
[100]杨世勇,黄永杰,张敏,等.重金属对昆虫的生态生理效应[J].昆虫学报,2015,58(4):427-436Yang S Y,Huang Y J,Zhang M,et al.Ecophysiological effects of heavy metals on insects[J].Acta Entomologica Sinica,2015,58(4):427-436(in Chinese)
[101]陆慧贤,徐永健.镉胁迫下缢蛏(Sinonovacula constricta)抗氧化酶活性及DNA损伤的研究[J].海洋环境科学,2011,30(1):96-101Lu H X,Xu Y J.Effects of cadmium on antioxidant enzyme activity and DNA damage in Sinonovacula constricta[J].Marine Environmental Science,2011,30(1):96-101(in Chinese)
[102]周建民,党志,蔡美芳,等.大宝山矿区污染水体中重金属的形态分布及迁移转化[J].环境科学研究,2005,18(3):5-10Zhou J M,Dang Z,Cai M F,et al.Speciation distribution and transfer of heavy metals in contaminated stream waters around dabaoshan mine[J].Research of Environmental Sciences,2005,18(3):5-10(in Chinese)
[103]Daniele M,Maria F B,Angela L,et al.Heavy metals in sediments from canals for water supplying and drainage:Mobilization and control strategies[J].Journal of Hazardous Materials,2008,161(2):723-729
[2]Fernandes A R,Mortimer D N,Rose M,et al.Occurrence of dioxins(PCDDs,PCDFs)and polychlorinated biphenyls(PCBs)in wild,farmed and processed fish,and shellfish[J].Food Additives&Contaminants Part B Surveillance,2009,2(1):15-20
[3]Rose M,Fernandes A,Mortimer D,et al.Contamination of fish in UK fresh water systems:Risk assessment for human consumption[J].Chemosphere,2015,122(10):183-189
[4]Sfakianakis D G,Renieri E,Kentouri M,et al.Effect of heavy metals on fish larvae deformities:A review[J].Environmental Research,2015,137:246-255
[5]Valko M,Morris H,Cronin M T.Metals,toxicity and oxidative stress[J].Current Medicinal Chemistry,2005,12(10):1161-1208
[6]Islam M S,Tanaka M.Impacts of pollution on coastal and marine ecosystems including coastal and marine fisheries and approach for management:A review and synthesis[J].Systematic Biology,2004,48(7-8):624-649
[7]Mohanty D,Samanta L.Multivariate analysis of potential biomarkers of oxidative stress in Notopterus notopterus tissues from Mahanadi River as a function of concentration of heavy metals[J].Chemosphere,2016,155:28-38
[8]韦丽丽,周琼,谢从新,等.三峡库区重金属的生物富集、生物放大及其生物因子的影响[J].环境科学,2016,37(1):325-334Wei L L,Zhou Q,Xie C X,et al.Bioaccumulation and biomagnification of heavy metal in Three Gorges Reservoir and effect of biological factors[J].Envioronmentd Science,2016,37(1):325-334(in Chinese)
[9]王宏镔,束文圣,蓝崇钰.重金属污染生态学研究现状与展望[J].生态学报,2005,25(3):596-605Wang H B,Shu W S,Lan C Y.Ecology for heavy metal pollution:Recent advances and future prospects[J].Acta Ecologica Sinica,2005,25(3):596-605(in Chinese)
[10]Mann R M,Hyne R V,Choung C B,et al.Amphibians and agricultural chemicals:Review of the risks in a complex environment[J].Environmental Pollution,2009,157(11):2903-2927
[11]刘健康.高级水生生物学[M].北京:科学出版社,1999:224-225Liu J K.Advanced Aquatic Biology[M].Beijing:Science Press,1999:224-225(in Chinese)
[12]张义贤.重金属对大麦(Hordeum vulgare)毒性的研究[J].环境科学学报,1997(2):199-205Zhang Y X.Toxicity of heavy metals to Hordeum vulgare[J].Acta Scientiae Circumstantiae,1997(2):199-205(Chinese)
[13]胡金朝.重金属污染对不同生境水生植物的毒害机理研究[D].南京:南京师范大学,2006:10-21Hu J Z.The toxic mechanism study of heavy metal pollution on aquatic plant under different growth conditions[D].Nanjing:Nanjing Normal University,2006:10-21(in Chinese)
[14]Zhang W,Tan N G J,Fu B,et al.Metallomics and NMR-based metabolomics of Chlorella sp.reveal the synergistic role of copper and cadmium in multi-metal toxicity and oxidative stress[J].Metallomics,2015,7(3):426-438
[15]Prado C,Rodríguez-Montelongo L,González J A,et al.Uptake of chromium by Salvinia minima:Effect on plant growth,leaf respiration and carbohydrate metabolism[J].Journal of Hazardous Materials,2010,177(1-3):546-553
[16]Vesel'y T,SzákováP T J.The use of water lettuce(Pistia stratiotes L.)for rhizofiltration of a highly polluted solution by cadmium and lead[J].International Journal of Phytoremediation,2011,13(9):859-872
[17]涂俊芳,储昭霞,欧智涛,等.Zn/Pb与Cr单一胁迫下青萍的生长状况及其富集能力[J].生物学杂志,2015,32(4):38-42Tu J F,Chu Z X,Ou Z T,et al.Growth and bioaccumulation of Lemna minor exposed to Zn,Pb and Cr[J].Journal of Biology,2015,32(4):38-42(in Chinese)
[18]Malar S,Sahi S V,Favas P J C,et al.Mercury heavymetal-induced physiochemical changes and genotoxic alterations in water hyacinths[Eichhornia crassipes,(Mart.)][J].Environmental Science&Pollution Research,2015,22(6):4597-4608
[19]Samardakiewicz S,Wozny A.Cell division in Lemna minor roots treated with lead[J].Aquatic Botany,2005,83(3):289-295
[20]Basile A,Sorbo S,Cardi M,et al.Effects of heavy metals on ultrastructure and Hsp70 induction in Lemna minor L.exposed to water along the Sarno River,Italy[J].Ecotoxicology and Environmental Safety,2015,114:93-101
[21]Zhang W,Tan N G,Fu B,et al.Metallomics and NMR-based metabolomics of Chlorella sp.reveal the synergistic role of copper and cadmium in multi-metal toxicity and oxidative stress[J].Metallomics Integrated Biometal Science,2015,7(3):426-438
[22]Gupta M,Sarin N B.Heavy metal induced DNA changes in aquatic macrophytes:Random amplified polymorphic DNA analysis and identification of sequence characterized amplified region marker[J].Journal of Environmental Sciences,2009,21(5):686-690
[23]陈雷,郑青松,刘兆普,等.不同Cu2+浓度处理对斜生栅藻生长及叶绿素荧光特性的影响[J].生态环境学报,2009,18(4):1231-1235Chen L,Zheng Q S,Liu Z P,et al.Effects of different concentrations of copper ion on the growth and chlorophyll fluorescence characteristics of Scendesmus obliquus[J].Ecology and Environment,2009,18(4):1231-1235(in Chinese)
[24]简敏菲,汪斯琛,余厚平,等.Cd2+、Cu2+胁迫对黑藻(Hydrilla verticillata)的生长及光合荧光特性的影响[J].生态学报,2016,36(6):1719-1727Jian M F,Wang S C,Yu H P,et al.Influence of Cd2+or Cu2+stress on the growth and photosynthetic fluorescence characteristics of Hydrilla verticillata[J].Acta Ecologica Sinica,2016,36(6):1719-1727(in Chinese)
[25]樊香绒,尹黎燕,李伟,等.不同价态砷对斜生栅藻生长及叶绿素荧光的影响[J].水生态学杂志,2013,34(5):60-64Fan X R,Yin L Y,Li W,et al.Effect of arsenic species on the growth and chlorophyll fluorescence characteristics of Scenedesmus obliquus[J].Journal of Hydroecology,2013,34(5):60-64(in Chinese)
[26]Deng G,Li M,Li H,et al.Exposure to cadmium causes declines in growth and photosynthesis in the endangered aquatic fern(Ceratopteris pteridoides)[J].A-quatic Botany,2014,112(112):23-32
[27]潘义宏,王宏镔,谷兆萍,等.大型水生植物对重金属的富集与转移[J].生态学报,2010,30(23):6430-6441Pan Y H,Wang H B,Gu Z P,et al.Accumulation and translocation of heavy metals by macrophytes[J].Acta Ecologica Sinica,2010,30(23):6430-6441(in Chinese)
[28]Rezania R,Taib S M,Din M F M,et al.Comprehensive review on phytotechnology:Heavy metals removal by diverse aquatic plants species from wastewater[J].Journal of Hazardous Materials,2016,318:587-599
[29]Solanki R,Dhankhar R.Biochemical changes and adaptive strategies of plants under heavy metal stress[J].Biologia,2011,66(66):195-204
[30]Hall J L.Cellular mechanisms for heavy metal detoxification and tolerance[J].Journal of Experimental Botany,2002,53(366):1-11
[31]Piotrowska A,Bajguz A,Godlewska-Z·ykiewicz B,et al.Changes in growth,biochemical components,and antioxidant activity in aquatic plant Wolffia arrhiza(Lemnaceae)exposed to cadmium and lead[J].Archives of Environmental Contamination&Toxicology,2010,58(3):594-604
[32]Morel J L,Mench M,Guckert A.Measurement of Pb2+,Cu2+and Cd2+binding with mucilage exudates from maize(Zea mays L.)roots[J].Biology&Fertility of Soils,1986,2(1):29-34
[33]Xin W,Liu Y G,Zeng G M,et al.Subcellular distribution and chemical forms of cadmium in Bechmeria nivea(L.)Gaud[J].Environmental&Experimental Botany,2008,62(3):389-395
[34]Monteiro C M,Castro P M L,Malcata F X.Metal uptake by microalgae:Underlying mechanisms and practical applications[J].Biotechnology Progress,2012,28(2):299-311
[35]Kramer U.Cadmium for all meals-plants with an unusual appetite[J].New Phytologist,2000,145(1):1-3
[36]Oveˇc ka M,Takáˇc T.Managing heavy metal toxicity stress in plants:Biological and biotechnological tools[J].Biotechnology Advances,2014,32(1):73-86
[37]Liu Z,Gu C,Chen F,et al.Heterologous expression of a Nelumbo nucifera phytochelatin synthase gene enhances cadmium tolerance in Arabidopsis thaliana[J].Applied Biochemistry&Biotechnology,2012,166(3):722-734
[38]Xu W,Shi W,Yan F,et al.Mechanisms of cadmium detoxification in cattail(Typha angustifolia L.)[J].A-quatic Botany,2011,94(1):37-43
[39]Kumar K S,Dahms H U,Won E J,et al.Microalgae-Apromising tool for heavy metal remediation[J].Ecotoxicology&Environmental Safety,2015,113:329-352
[40]Islam E,Khan M T,Irem S.Biochemical mechanisms of signaling:Perspectives in plants under arsenic stress[J].Ecotoxicology&Environmental Safety,2015,114:126-133
[41]Haq N U,Raza S,Luthe D S,et al.A dual role for the chloroplast small heat shock protein of Chenopodium album,including protection from both heat and metal stress[J].Plant Molecular Biology Reporter,2013,31(2):398-408
[42]袁秋红.重金属对水生植物抗氧化系统的影响及重金属胁迫蛋白研究[D].南京:南京师范大学,2008:14Yuan Q H.The study on effect of antioxidant system of heavy metals on the aquatic plants and heavy metal stress protein[D].Nanjing:Nanjing Normal University,2008:14(in Chinese)
[43]Kuyucak N,Volesky B.Biosorbents for recovery of metals from industrial solutions[J].Biotechnology Letters,1988,10(2):137-142
[44]刘清泉,陈亚华,沈振国,等.细胞壁在植物重金属耐性中的作用[J].植物生理学报,2014,50(5):605-611Liu Q Q,Chen Y H,Shen Z G,et al.Roles of cell wall in plant heavy metal tolerance[J].Plant Physiology Journal,2014,50(5):605-611(in Chinese)
[45]Soldo D,Hari R,Sigg L,et al.Tolerance of Oocystis nephrocytioides to copper:Intracellular distribution and extracellular complexation of copper[J].Aquatic Toxicology,2005,71(4):307-317
[46]Nies D H,Silver S.Ion efflux systems involved in bacterial metal resistances[J].Journal of Industrial Microbiology,1995,14(2):186-199
[47]Ishaque A B,Linda J,Tonya G,et al.Assessment of individual and combined toxicities of four non-essential metals(As,Cd,Hg and Pb)in the microtox assay[J].International Journal of Environmental Research&Public Health,2006,3(1):118-120
[48]Wada S,Suziki S.Inhibitory effect of zinc on the remineralisation of dissolved organic matter in the coastal environment[J].Aquatic Microbial Ecology,2011,63(1):47-59
[49]Giller K E,Witter E,Mcgrath S P.Toxicity of heavy metals to microorganisms and microbial processes in agricultural soils:A review[J].Soil Biology&Biochemistry,1998,30(10-11):1389-1414
[50]Taylor M G,Simkiss K,Greaves G N,et al.Corrosion of intracellular granules and cell death[J].Royal Society of London Proceedings,1988,234(1277):463-476
[51]刘瑞霞,汤鸿霄,劳伟雄.重金属的生物吸附机理及吸附平衡模式研究[J].化学进展,2002,14(2):87-92Liu R X,Tang H X,Lao W X.Advances in biosorption mechanism and equilibrium modeling for heavy metals on biomaterials[J].Progress in Chemistry,2002,14(2):87-92(in Chinese)
[52]张甲耀.环境微生物学(下)[M].武汉:武汉大学出版社,2008:127-128Zhang J Y.Environmental Microbiology(2)[M].Wuhan:Wuhan University Press,2008:127-128(in Chinese)
[53]Houba C,Remacle J.Composition of the saprophytic bacterial communities in freshwater systems contaminated by heavy metals[J].Microbial Ecology,1980,6(1):55-69
[54]陈素华,孙铁珩,周启星,等.微生物与重金属间的相互作用及其应用研究[J].应用生态学报,2002,13(2):239-242Chen S H,Sun T H,Zhou Q X,et al.Interaction between microorganisms and heavy metals and its application[J].Chinese Journal of Applied Ecology,2002,13(2):239-242(in Chinese)
[55]孙晋伟,黄益宗,石孟春,等.土壤重金属生物毒性研究进展[J].生态学报,2008,28(6):2861-2869Sun J W,Huang Y Z,Shi M C,et al.The review of heavy metals biotoxicity[J].Acta Ecologica Sinica,2008,28(6):2861-2869(in Chinese)
[56]Wang C,Shan B,Zhang H,et al.Limitation of spatial distribution of ammonia-oxidizing microorganisms in the Haihe River,China,by heavy metals[J].Journal of Environmental Sciences,2014,26(3):502-511
[57]Zhou S,Wei C H,Liao C D,et al.Damage to DNA of effective microorganisms by heavy metals:Impact on wastewater treatment[J].Journal of Environmental Sciences,2008,20(12):1514-1518
[58]Ozdemir G,Ozturk T,Ceyhan N,et al.Heavy metal biosorption by biomass of Ochrobactrum anthropi producing exopolysaccharide in activated sludge[J].Bioresource Technology,2003,90(1):71-74
[59]丁为群,刘迪秋,葛锋,等.鱼类对重金属胁迫的分子反应机理[J].生物学杂志,2012,29(2):84-87Ding W Q,Liu D Q,Ge F,et al.The molecular mechanism by heavy metal stress in fish[J].Journal of Biology,2012,29(2):84-87(in Chinese)
[60]Craig A,Hare L,Tessier A.Experimental evidence for cadmium uptake via calcium channels in the aquatic insect Chironomus staegeri[J].Aquatic Toxicology,1999,44(98):255-262
[61]杜建国,赵佳懿,陈彬,等.应用物种敏感性分布评估重金属对海洋生物的生态风险[J].生态毒理学报,2013,8(4):561-570Du J G,Zhao J Y,Chen B,et al.Assessing eological risks of heavy metals to marine organisms by species sensitivity distributions[J].Asian Journal of Ecotoxicology,2013,8(4):561-570(in Chinese)
[62]Bian B,Zhou Y,Fang B B.Distribution of heavy metals and benthic macroinvertebrates:Impacts from typical inflow river sediments in the Taihu Basin,China[J].Ecological Indicators,2016,69:348-359
[63]Javed M,Usmani N.Impact of heavy metal toxicity on hematology and glycogen status of fish:A review[J].Proceedings of the National Academy of Sciences,India-Section B:Biological Sciences,2014,85(4):889-900
[64]Agrawal S J,Srivastava A K,Chaudhry H S.Haematological effects of nickel toxicity on a fresh water teleost,Colisa fasciatus[J].Acta Pharmacologica et Toxicologica,1979,45(3):215-217
[65]Tripathi S,Mishra B B,Tripathi S P.Effect of heavy metal cadmium sulphate on the toxicity and biochemical parameters of reproductive cycle of Colisa fasciatus[J].Researcher,2012,4(4):65-68
[66]Ryvolova M,Krizkova S,Adam V,et al.Analytical methods for metallothionein detection[J].Current Analytical Chemistry,2011,700(3):243-261
[67]Fatima M,Usmani N,Firdaus F,et al.In vivo induction of antioxidant response and oxidative stress associated with genotoxicity and histopathological alteration in two commercial fish species due to heavy metals exposure in northern India(Kali)river[J].Comparative Biochemistry&Physiology Part C Toxicology&Pharmacology,2015,176-177:17-30
[68]Morcillo P,Esteban M,Cuesta A.Heavy metals produce toxicity,oxidative stress and apoptosis in the marine teleost fish SAF-1 cell line.[J].Chemosphere,2015,144:225-233
[69]马京津,徐团,轩瑞晶,等.铅对河南华溪蟹卵巢抗氧化酶活力和脂质过氧化水平的影响[J].环境科学学报,2012,32(9):2346-2352Ma J J,Xu T,Xuan R J,et al.Effects of lead on ovaries lipid peroxidation level and antioxidant enzyme activity in freshwater crab Sinopotamon henanense[J].Acta Scientiae Circumstantiae,2012,32(9):2346-2352(in Chinese)
[70]Kim B M,Rhee J S,Jeong C B,et al.Heavy metals induce oxidative stress and trigger oxidative stress-mediated heat shock protein(hsp)modulation in the intertidal copepod Tigriopus japonicus[J].Comparative Biochemistry&Physiology Part C Toxicology&Pharmacology,2014,166(1):65-74
[71]殷健.重金属对斑马鱼的毒性效应及作用机制研究[D].北京:北京协和医学院,2014:53Yin J.Studies on toxic effect and mechanism of heavy metals on zebrafish[D].Beijing:Peking Union Medical College,2014:53(in Chinese)
[72]Morcillo P,Cordero H,Meseguer J,et al.Toxicological in vitro effects of heavy metals on gilthead seabream(Sparus aurata L.)head-kidney leucocytes[J].Toxicology in Vitro,2015,30(1):412-420
[73]Handy R D.Chronic effects of copper exposure versus endocrine toxicity:Two sides of the same toxicological process?[J].Comparative Biochemistry&Physiology Part A Molecular&Integrative Physiology,2003,135(1):25-38
[74]韩雨薇,张彦峰,陈萌,等.沉积物中重金属Pb和Cd对河蚬的毒性效应研究[J].生态毒理学报,2015,10(4):129-137Han Y W,Zhang Y F,Chen M,et al.Toxicity of Pb,Cd-spiked freshwater sediments to Corbicula fluminea[J].Asian Journal of Ecotoxicology,2015,10(4):129-137(in Chinese)
[75]沈洪艳,曹志会,张红燕,等.淡水沉积物中Cd和Cu对河蚬的毒性效应研究[J].中国环境科学,2016,36(1):286-292Shen H Y,Cao Z H,Zhang H Y,et al.The toxic effects of Cd and Cu in freshwater sediments on Corbicula fluminea[J].China Environmental Science,2016,36(1):286-292(in Chinese)
[76]Morcillo P,Cordero H,Meseguer J,et al.In vitro immunotoxicological effects of heavy metals on European sea bass(Dicentrarchus labrax L.)head-kidney leucocytes.[J].Fish&Shellfish Immunology,2015,47(1):245-254
[77]Witeska M,Sarnowski P,ugowska K,et al.The effects of cadmium and copper on embryonic and larval development of ide Leuciscus idus L.[J].Fish Physiology&Biochemistry,2013,40(1):151-163
[78]穆景利,王莹,王新红,等.Cd2+、Hg2+、Cr6+和Pb2+对黑点青鳉(Oryzias melastigma)早期生活阶段的毒性效应研究[J].生态毒理学报,2011,6(4):352-360Mu J,Wang Y,Wang X,et al.Toxic effects of cadmium,mercury,chromium and lead on the early life stage of marine medaka(Oryzias melastigma)[J].Asian Journal of Ecotoxicology,2011,6(4):352-360(in Chinese)
[79]Jezierska B,ugowska K,Witeska M.The effects of heavy metals on embryonic development of fish(a review)[J].Fish Physiology and Biochemistry,2009,35(4):625-640
[80]孙翰昌,徐敬明,甘桂云.4种重金属对禾花鱼胚胎的毒性效应[J].水生态学杂志,2013,34(1):92-95Sun H C,Xu J M,Gan G Y.Toxicity effects of four heavy metals on the embryo of Procypris merus[J].Journal of Hydroecology,2013,34(1):92-95(in Chinese)
[81]章强,辛琦,强丽媛,等.铜及其与四环素的联合暴露对斑马鱼胚胎的毒性效应[J].生态毒理学报,2015,10(5):35-46Zhang Q,Xin Q,Qiang L Y,et al.Developmental toxicity of Cu and tetracycline on zebrafish embryos(Danio rerio)[J].Asian Journal of Ecotoxicology,2015,10(5):35-46(in Chinese)
[82]Kessabi K,Kerkeni A,Sa6d K,et al.Involvement of Cd bioaccumulation in spinal deformities occurrence in natural populations of mediterranean killifish[J].Biological Trace Element Research,2008,128(1):72-81
[83]Lourduraj A V,Azhagu M,Peranandam R,et al.The application of histocytopathological biomarkers in the mud crab Scylla serrata(Forskal)to assess heavy metal toxicity in Pulicat Lake,Chennai[J].Marine Pollution Bulletin,2014,81(1):85-93
[84]Kong X,Jiang H,Wang S,et al.Effects of copper exposure on the hatching status and antioxidant defense at different developmental stages of embryos and larvae of goldfish Carassius auratus[J].Chemosphere,2013,92(11):1458-1464
[85]Barjhoux I,Baudrimont M,Morin B,et al.Effects of copper and cadmium spiked-sediments on embryonic development of Japanese medaka(Oryzias latipes)[J].Ecotoxicology&Environmental Safety,2012,79(79):272-282
[86]张迎梅,王叶菁,虞闰六,等.重金属Cd2+、Pb2+和Zn2+对泥鳅DNA损伤的研究[J].水生生物学报,2006,30(4):399-403Zhang Y M,Wang Y J,Yu R L,et al.Effects of heavy metals Cd2+,Pb2+and Zn2+on and damage of loach Misgurnus anguillicandatus[J].Acta Hydrobiologica Sinica,2006,30(4):399-403(in Chinese)
[87]Ahmed M K,Kundu G K,Al-Mamun M H,et al.Chromium(VI)induced acute toxicity and genotoxicity in freshwater stinging catfish,Heteropneustes fossilis[J].Ecotoxicology&Environmental Safety,2013,92(3):64-70
[88]张德莉,朱圣姬,罗光富,等.自由基与DNA氧化损伤的研究进展[J].三峡大学学报:自然科学版,2004,26(6):563-567Zhang D L,Zhu S J,Luo G F,et al.Development of free radical-induced oxidative damage to DNA[J].Journal of China Three Gores University:Natural Sciences,2004,26(6):563-567(in Chinese)
[89]韩照祥,许兴友,谢惠珠.重金属与鲑鱼精DNA作用的比较研究[J].农业环境科学学报,2007,26(1):164-169Han Z X,Xu X Y,Xie H Z.Interaction between heavy metals and the DNA from salmon sperm[J].Journal of Agro-environment Science,2007,26(1):164-169(in Chinese)
[90]Bandyopadhyay A.Sensitivity of Allium and Nicotiana in cellular and acellular comet assays to assess differential genotoxicity of direct and indirect acting mutagens[J].Ecotoxicology&Environmental Safety,2011,74(4):860-865
[91]Giaginis C,Gatzidou E,Theocharis S.DNA repair systems as targets of cadmium toxicity[J].Toxicology&Applied Pharmacology,2006,213(3):282-290
[92]Dai W,Fu L,Du H,et al.Effects of montmorillonite on Pb accumulation,oxidative stress,and DNA damage in tilapia(Oreochromis niloticus)exposed to dietary Pb[J].Biological Trace Element Research,2010,136(1):71-78
[93]郭勇勇,华江环,杨丽华,等.三峡库区水样中重金属含量及其对斑马鱼胚胎发育的毒性评价[J].水生生物学报,2015,39(5):885-892Guo Y Y,Hua J H,Yang L H,et al.Analysis of heavy metals in the surface water from the Three Gorges Reservoir and its toxic effects on the embryonic development of the zebrafish[J].Acta Hydrobiologica Sinica,2015,39(5):885-892(in Chinese)
[94]Vandegehuchte M B,Vandenbrouck T,Coninck D D,et al.Gene transcription and higher-level effects of multigenerational Zn exposure in Daphnia magna[J].Chemosphere,2010,80(9):1014-1020
[95]盛樟,竺俊全.水生动物金属硫蛋白分子毒理学研究进展[J].生物学杂志,2014,31(2):77-81Sheng Z,Zhu J Q.Research progress on molecular toxicology of metallothionein in aquatic animals[J].Journal of Biology,2014,31(2):77-81(in Chinese)
[96]Mao H,Tan F Q,Wang D H,et al.Expression and function analysis of metallothionein in the testis of stone crab Charybdis japonica exposed to cadmium[J].A-quatic Toxicology,2012,124-125(12):11-21
[97]Liu J,Ma L,Yin S,et al.Effects of Ce3+on conformation and activity of superoxide dismutase[J].Biological Trace Element Research,2008,125(2):170-178
[98]Rhee J S,Kim B M,Jeong C B,et al.Development of enzyme-linked immunosorbent assay(ELISA)for glutathione S-transferase(GST-S)protein in the intertidal copepod Tigriopus japonicus and its application for environmental monitoring[J].Chemosphere,2013,93(10):2458-2466
[99]孙元敏,马志远,黄海萍.我国海岛潮间带贝类体中重金属含量及其评价[J].中国环境科学,2015,35(2):574-578Sun Y M,Ma Z Y,Huang H P.Contamination and assessment of heavy metals shellfish in the intertidal zone of sea islands in China[J].China Environmental Science,2015,35(2):574-578(in Chinese)
[100]杨世勇,黄永杰,张敏,等.重金属对昆虫的生态生理效应[J].昆虫学报,2015,58(4):427-436Yang S Y,Huang Y J,Zhang M,et al.Ecophysiological effects of heavy metals on insects[J].Acta Entomologica Sinica,2015,58(4):427-436(in Chinese)
[101]陆慧贤,徐永健.镉胁迫下缢蛏(Sinonovacula constricta)抗氧化酶活性及DNA损伤的研究[J].海洋环境科学,2011,30(1):96-101Lu H X,Xu Y J.Effects of cadmium on antioxidant enzyme activity and DNA damage in Sinonovacula constricta[J].Marine Environmental Science,2011,30(1):96-101(in Chinese)
[102]周建民,党志,蔡美芳,等.大宝山矿区污染水体中重金属的形态分布及迁移转化[J].环境科学研究,2005,18(3):5-10Zhou J M,Dang Z,Cai M F,et al.Speciation distribution and transfer of heavy metals in contaminated stream waters around dabaoshan mine[J].Research of Environmental Sciences,2005,18(3):5-10(in Chinese)
[103]Daniele M,Maria F B,Angela L,et al.Heavy metals in sediments from canals for water supplying and drainage:Mobilization and control strategies[J].Journal of Hazardous Materials,2008,161(2):723-729