湿热证黄腻苔与糖尿病相关性分析
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摘要
舌诊是通过舌质和舌苔的变化以诊察疾病的方法。舌苔是由脾胃之气上蒸而成,根据邪气的寒热虚实不同,舌苔的病理性表现亦有所差异。黄腻苔为湿热证的特征性表现之一,司外揣内,而预判疾病的变化。糖尿病的发病与多种因素有关,其病因和发病机制有待进一步探究。近年来,中医舌诊的研究逐渐向微观化、客观化、标准化方向深入,文章主要以湿热证黄腻苔为立论点,从其成因、现代研究、病因病机、菌群的变化及炎症因子等方面并结合临床验案,探讨其与糖尿病之间的相关性,以期为后续的临床治疗提供证据支持,从而辅助疾病的判断与治疗。
Tongue diagnosis is a method of examining diseases through changes in the tongue and tongue. The tongue coating is steamed from the spleen and stomach. According to the cold and heat of the evil spirits,the pathological manifestations of the tongue coating are also different. Yellow-scarred moss is one of the characteristic symptoms of damp-heat syndrome,and it is predicted to change the disease. The incidence of diabetes is related to many factors,and its etiology and pathogenesis need to be further explored. In recent years,the research on tongue diagnosis of traditional Chinese medicine has gradually penetrated into the direction of microscopic,objectification and standardization. This paper mainly focuses on the damp heat syndrome of yellow greasy moss,from its causes,modern research,pathogenesis and pathogens,changes in flora and inflammatory factors. In addition,combined with Professor FENG Zhihai's treatment case,explore the correlation between it and diabetes,in order to provide evidence support for subsequent clinical treatment,thus assisting in the judgment and treatment of the disease.
Tongue diagnosis is a method of examining diseases through changes in the tongue and tongue. The tongue coating is steamed from the spleen and stomach. According to the cold and heat of the evil spirits,the pathological manifestations of the tongue coating are also different. Yellow-scarred moss is one of the characteristic symptoms of damp-heat syndrome,and it is predicted to change the disease. The incidence of diabetes is related to many factors,and its etiology and pathogenesis need to be further explored. In recent years,the research on tongue diagnosis of traditional Chinese medicine has gradually penetrated into the direction of microscopic,objectification and standardization. This paper mainly focuses on the damp heat syndrome of yellow greasy moss,from its causes,modern research,pathogenesis and pathogens,changes in flora and inflammatory factors. In addition,combined with Professor FENG Zhihai's treatment case,explore the correlation between it and diabetes,in order to provide evidence support for subsequent clinical treatment,thus assisting in the judgment and treatment of the disease.
引文
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[3]陈鑫,张菁.西格列汀在糖尿病治疗中的药理作用及临床评价[J].中国医药,2018,13(3):467-470.
[4]李娟,岳仁宋.消渴病从湿热论治[J].四川中医,2013,31(2):43-45.
[5]贺宏波,闫韶哗,杨玲玲,等. 5930例2型糖尿病患者舌象与实验室指标相关性分析[J].中医杂志,2013,54(23):2031-2034.
[6]王露,高键,王忆勤,等.数字化舌诊对2型糖尿病患者血糖水平、营养状况及膳食结构的评估作用[J].上海中医药杂志,2011,45(6):25-27.
[7]刘国用.舌苔与糖尿病小议[J].中医药导报,2008,14(11):61.
[8]王仁和,石岩.消渴病瘀热证理论探讨[J].南京中医药大学学报,2017,33(4):325-327.
[9]张晓阳,郭赛珊,张孟仁,等.308例2型糖尿病中医临床证型调查分析[J].北京中医药大学学报,2008,31(6):420-423.
[10]丁曦,姚定国.2型糖尿病肥胖患者血糖胰岛素指标及中医辨证特征[J].中华中医药学刊,2010,28(9):1963-1964.
[11]朱莲娜,黄李平,吕军影,等.微生态学方法在湿热证舌苔微生物群研究中的应用[J].广西医学,2009,31(4):480-482.
[12]阙铁生,卓冬婷,吕军影,等.脾胃湿热证黄腻苔与舌上皮细胞凋亡和细菌总数的关系探讨[J].时珍国医国药,2011,22(3):692-693.
[13]刘海霞,李晶,刘奔,等.阿卡波糖对2型糖尿病患者粪便中双歧杆菌数量的影响[J].中华内分泌代谢杂志,2011,27(11):928-931.
[14]刘林,吕文亮.2型糖尿病发病机理与湿热关系的探讨[J].湖北中医学院学报,2004,6(1):29-30.
[15]裴文丽,姚定国,徐翀颖.湿热困脾型糖尿病胰岛素抵抗与IL-6的关系[J].云南中医中药杂志,2011,32(3):10-11.
[16]石艳刚,高天舒,崔鹏,等.新诊断2型糖尿病湿热困脾证与IL-6的关系研究[J].国际中医中药杂志,2009,31(6):512-513.
[17]李小维,李万根,田耕,等.孕前期血浆脂联素及TNF-α与妊娠期糖尿病的发病风险[J].广东医学,2009,30(6):906-907.
[18] Kirwan J P,Hauguel-De Mouzon S,Lepercq J,et al. TNF-alpha is apredictor of insulin resistance in human pregnancy[J]. Diabetes,2002,51(7):2207-2213.
[19]陈书英,王光慧,赵馨,等.TNF-α基因多态性与妊娠期糖尿病相关性研究[J].徐州医学院学报,2016,36(10):648-651.
[20]赵有成,魏宏建,段勇.重症感染者血中IL-6和TNF-α检测的意义[J].中国抗感染化疗杂志,2003,3(5):315-317.
[21]金明华,秦鉴,丘瑞香.白腻苔和黄腻苔患者血SOD、MDA水平的变化[J].中国中医药科技,2003,10(3):131.
[22]张平,水文霞,杜月光.黄腻苔舌脱落上皮细胞的形态计量分析[J].中国体视学与图像分析,2001,6(1):13-15,19.
[2] Lopez-Pintor RM,Casanas E,Gonzalez-Serrano J,et al. Xerosto-mia,Hyposalivation,and Salivary Flow in Diabetes Patients[J].J Di-abetes Res,2016:1-15.
[3]陈鑫,张菁.西格列汀在糖尿病治疗中的药理作用及临床评价[J].中国医药,2018,13(3):467-470.
[4]李娟,岳仁宋.消渴病从湿热论治[J].四川中医,2013,31(2):43-45.
[5]贺宏波,闫韶哗,杨玲玲,等. 5930例2型糖尿病患者舌象与实验室指标相关性分析[J].中医杂志,2013,54(23):2031-2034.
[6]王露,高键,王忆勤,等.数字化舌诊对2型糖尿病患者血糖水平、营养状况及膳食结构的评估作用[J].上海中医药杂志,2011,45(6):25-27.
[7]刘国用.舌苔与糖尿病小议[J].中医药导报,2008,14(11):61.
[8]王仁和,石岩.消渴病瘀热证理论探讨[J].南京中医药大学学报,2017,33(4):325-327.
[9]张晓阳,郭赛珊,张孟仁,等.308例2型糖尿病中医临床证型调查分析[J].北京中医药大学学报,2008,31(6):420-423.
[10]丁曦,姚定国.2型糖尿病肥胖患者血糖胰岛素指标及中医辨证特征[J].中华中医药学刊,2010,28(9):1963-1964.
[11]朱莲娜,黄李平,吕军影,等.微生态学方法在湿热证舌苔微生物群研究中的应用[J].广西医学,2009,31(4):480-482.
[12]阙铁生,卓冬婷,吕军影,等.脾胃湿热证黄腻苔与舌上皮细胞凋亡和细菌总数的关系探讨[J].时珍国医国药,2011,22(3):692-693.
[13]刘海霞,李晶,刘奔,等.阿卡波糖对2型糖尿病患者粪便中双歧杆菌数量的影响[J].中华内分泌代谢杂志,2011,27(11):928-931.
[14]刘林,吕文亮.2型糖尿病发病机理与湿热关系的探讨[J].湖北中医学院学报,2004,6(1):29-30.
[15]裴文丽,姚定国,徐翀颖.湿热困脾型糖尿病胰岛素抵抗与IL-6的关系[J].云南中医中药杂志,2011,32(3):10-11.
[16]石艳刚,高天舒,崔鹏,等.新诊断2型糖尿病湿热困脾证与IL-6的关系研究[J].国际中医中药杂志,2009,31(6):512-513.
[17]李小维,李万根,田耕,等.孕前期血浆脂联素及TNF-α与妊娠期糖尿病的发病风险[J].广东医学,2009,30(6):906-907.
[18] Kirwan J P,Hauguel-De Mouzon S,Lepercq J,et al. TNF-alpha is apredictor of insulin resistance in human pregnancy[J]. Diabetes,2002,51(7):2207-2213.
[19]陈书英,王光慧,赵馨,等.TNF-α基因多态性与妊娠期糖尿病相关性研究[J].徐州医学院学报,2016,36(10):648-651.
[20]赵有成,魏宏建,段勇.重症感染者血中IL-6和TNF-α检测的意义[J].中国抗感染化疗杂志,2003,3(5):315-317.
[21]金明华,秦鉴,丘瑞香.白腻苔和黄腻苔患者血SOD、MDA水平的变化[J].中国中医药科技,2003,10(3):131.
[22]张平,水文霞,杜月光.黄腻苔舌脱落上皮细胞的形态计量分析[J].中国体视学与图像分析,2001,6(1):13-15,19.