甲状腺癌患者行甲状腺全切术或近全切术的对比研究
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摘要
目的观察并对比甲状腺癌患者行甲状腺全切术与近全切术治疗的临床效果,比较两种术式的特点。方法选取我院2010年1月~2015年1月收治的甲状腺癌患者共90例,依据手术方式不同分为对照组与观察组,对照组采用甲状腺全切术治疗甲状腺癌,观察组采用甲状腺近全切术治疗甲状腺癌。治疗结束后比较两组患者甲状腺癌的治疗效果、复发率、转移率、并发症的发生情况。结果观察组患者甲状腺癌治疗的总有效率为88.6%,明显高于对照组总有效率71.7%,差异有统计学意义(P<0.05)。观察组甲状腺癌的复发率与对照组复发率差异无统计学意义(P>0.05)。观察组甲状腺癌转移率为2.3%,与对照组转移率差异无统计学意义(P>0.05)。但观察组低钙血症、声音嘶哑、甲状腺功能低下等并发症的发生率明显低于对照组,差异有统计学意义(P<0.05)。结论甲状腺近全切术与全切术对甲状腺癌复发与转移的影响无明显差异,但甲状腺近全切术治疗甲状腺癌总有效率较高,术后并发症发生率较低,安全有效,适合临床推广使用。
Objective To observe and compare the clinical effects and characteristics of hysterectomy and near total resection in the treatment of thyroid cancer. Methods A total of 90 patients with thyroid cancer were selected in our hospital from January 2010 to January 2015, the thyroid cancer patients were divided into control group and observation group according to different operation. The control group received total thyroidectomy method to cure for thyroid cancer, the observation group received near total resection to cure for thyroid thyroid cancer. After treatment, the incidence of treatment and the recurrence rate, metastasis rate of complications were compared in two groups. Results The total effective rate of the observation group of patients with thyroid cancer was 88.6%, significantly higher than 71.7% of the control group,the difference was statistically significant(P < 0.05).The recurrence rate in the control group and observation group had no significant difference(P > 0.05). The metastasis rate of thyroid cancer in the observation group was 2.3%, and there was no significant difference between the control group(P > 0.05). But the incidence of hypocalcemia observation group, hoarseness, thyroid dysfunction and other complications was significantly lower than the control group, the difference was statistically significant(P < 0.05). Conclusion Thyroid near total resection has no significant difference between hysterectomy effects on thyroid cancer recurrence and metastasis, but the thyroid gland near total resection of thyroid cancer have a higher overall efficiency, lower incidence of complications, safe and effective, suitable for clinical use.
Objective To observe and compare the clinical effects and characteristics of hysterectomy and near total resection in the treatment of thyroid cancer. Methods A total of 90 patients with thyroid cancer were selected in our hospital from January 2010 to January 2015, the thyroid cancer patients were divided into control group and observation group according to different operation. The control group received total thyroidectomy method to cure for thyroid cancer, the observation group received near total resection to cure for thyroid thyroid cancer. After treatment, the incidence of treatment and the recurrence rate, metastasis rate of complications were compared in two groups. Results The total effective rate of the observation group of patients with thyroid cancer was 88.6%, significantly higher than 71.7% of the control group,the difference was statistically significant(P < 0.05).The recurrence rate in the control group and observation group had no significant difference(P > 0.05). The metastasis rate of thyroid cancer in the observation group was 2.3%, and there was no significant difference between the control group(P > 0.05). But the incidence of hypocalcemia observation group, hoarseness, thyroid dysfunction and other complications was significantly lower than the control group, the difference was statistically significant(P < 0.05). Conclusion Thyroid near total resection has no significant difference between hysterectomy effects on thyroid cancer recurrence and metastasis, but the thyroid gland near total resection of thyroid cancer have a higher overall efficiency, lower incidence of complications, safe and effective, suitable for clinical use.
引文
[1]赵小立.总结甲状腺癌时甲状腺全切除或近全切除手术的操作经验[J].中国医药指南,2014,12(4):126.
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[4]王跃.改良甲状腺次全切除手术的临床疗效评价[J].中国医药科学,2014,4(13):188-190.
[5]武林枫,赵福龙,孟庆辉,等.甲状腺全切除术治疗结节性甲状腺肿的临床价值[J].中华普通外科杂志,2008,23(9):720-721.
[6]黎亮,黎慧,陈愉快,等.甲状腺峡部乳头状癌手术方式分析[J].中国医药科学,2014,3(21):219-220.
[7]杨民,沈美萍,陆辉,等.甲状腺癌患者甲状腺全切手术安全性探讨[J].中华普通外科杂志,2009,24(5):371-373.
[8]陈金花.甲状腺癌患者行甲状腺全切术或近全切术的疗效观察[J].临床合理用药杂志,2014,6(19):111.
[9]陈灏珠.实用内科学[M].北京:人民卫生出版社,2013:312-314,515.
[10]崔勇.甲状腺全切除或近全切除术治疗甲状腺癌的手术体会[J].中国实用医药,2013,8(33):119-120.
[11]吴元清.分析探讨甲状腺癌症患者行甲状腺全切术治疗与近全切术治疗的临床效果[J].延边医学,2015,2(149):50-51.
[12]梁艳君.甲状腺全切除或近全切除术治疗甲状腺癌疗效分析[J].医学信息,2014,27(8):526.
[13]廖洁.甲状腺全切与部分切除治疗甲状腺癌预后比较[J].中国现代医学杂志,2014,24(21):70-72.
[14]邢进,尚东.甲状腺全切除术与近全切除术治疗分化型甲状腺癌的效果分析[J].大连医科大学学报,2014,36(6):583-585.
[15]金善恩,卢仙球,周睿,等.精细化被膜解剖法在双侧甲状腺乳头状癌全切术中的应用(附25例报告)[J].浙江临床医学,2013,13(12):1840-1842.
[16]杨卫平,邵堂雷,陈伟国,等.甲状腺次全切除术后再行双侧全/近全切除术的探讨[J].中国实用外科杂志,2009,29(9):749-751.
[2]钟显峰,杨峰.甲状腺全切除或近全切除术治疗甲状腺癌的临床效果观察[J].中国实用医药,2014,9(12):44-45.
[3]李平.甲状腺癌时甲状腺全切除或近全切除手术的操作经验与体会[J].中国实用医药,2013,8(32):125-126.
[4]王跃.改良甲状腺次全切除手术的临床疗效评价[J].中国医药科学,2014,4(13):188-190.
[5]武林枫,赵福龙,孟庆辉,等.甲状腺全切除术治疗结节性甲状腺肿的临床价值[J].中华普通外科杂志,2008,23(9):720-721.
[6]黎亮,黎慧,陈愉快,等.甲状腺峡部乳头状癌手术方式分析[J].中国医药科学,2014,3(21):219-220.
[7]杨民,沈美萍,陆辉,等.甲状腺癌患者甲状腺全切手术安全性探讨[J].中华普通外科杂志,2009,24(5):371-373.
[8]陈金花.甲状腺癌患者行甲状腺全切术或近全切术的疗效观察[J].临床合理用药杂志,2014,6(19):111.
[9]陈灏珠.实用内科学[M].北京:人民卫生出版社,2013:312-314,515.
[10]崔勇.甲状腺全切除或近全切除术治疗甲状腺癌的手术体会[J].中国实用医药,2013,8(33):119-120.
[11]吴元清.分析探讨甲状腺癌症患者行甲状腺全切术治疗与近全切术治疗的临床效果[J].延边医学,2015,2(149):50-51.
[12]梁艳君.甲状腺全切除或近全切除术治疗甲状腺癌疗效分析[J].医学信息,2014,27(8):526.
[13]廖洁.甲状腺全切与部分切除治疗甲状腺癌预后比较[J].中国现代医学杂志,2014,24(21):70-72.
[14]邢进,尚东.甲状腺全切除术与近全切除术治疗分化型甲状腺癌的效果分析[J].大连医科大学学报,2014,36(6):583-585.
[15]金善恩,卢仙球,周睿,等.精细化被膜解剖法在双侧甲状腺乳头状癌全切术中的应用(附25例报告)[J].浙江临床医学,2013,13(12):1840-1842.
[16]杨卫平,邵堂雷,陈伟国,等.甲状腺次全切除术后再行双侧全/近全切除术的探讨[J].中国实用外科杂志,2009,29(9):749-751.