双通道视觉质量分析系统在单眼弱视患者中的应用
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摘要
目的运用双通道视觉质量分析系统分析单眼弱视患者弱视眼与非弱视眼的客观视觉质量。方法28例就诊的单眼弱视患者的双眼分别应用基于双通道技术的视觉质量分析系统(OQASTM II)进行测量,检测记录并分析以下参数:MTF截止空间频率(MTF cut off)、斯特列尔比值(strehl ratio,SR)、客观散射指数(objective scattering index,OSI)值、对比度分别为100%、20%和9%时的对比度视力(visual acuity,VA)值,并比较双眼之间的差异及造成两者差异的原因。结果非弱视眼DSI值与弱视眼比较,差异无统计学意义(P>0.05)。非弱视眼MTF cut off值、SR值与弱视眼比较,差异有统计学意义(P<0.05)。非弱视眼100%、20%、9%时VA值弱视眼比较,差异有统计学意义(P<0.05)。双眼视觉质量与患者年龄、最佳矫正视力、等效球镜无相关性(P<0.05)。结论双通道视觉质量分析系统可较全面、客观地评估弱视患者的视觉质量,对弱视患者的诊断提供临床客观依据。
Objective To compare the objective optical quality between monocular amblyopia eye and the eyes without amblyopia by means of double-pass optical quality analysis system( OQASTM II). Methods Twenty-eight patients with monocular amblyopia( both eyes) were examined by double-pass OQASTM II,the parameters including modulation transfer function cutoff frequency( MTFcut off),Strehl ratio( SR),objective scatter index( OSI),visual acuity( VA) in contrast degree of 100%,20%,9%,respectively,were detected and analyzed,moreover,the differences between two eyes and the causes were analyzed. Results There was no significant difference in DSI value between non-amblyopia eye and amblyopia eye( P > 0. 05). However there were significant differences in MTF cut off,SR value between non-amblyopia eye and amblyopia eye( P < 0. 05),moreover,there was significant difference in VA value in contrast degree of 100%,20%,9%,respectively between non-amblyopia eye and amblyopia eye( P < 0. 05),Besides binocular vision was not correlated to patient's age,optimized corrected vision and equivalent spherical lens( P > 0. 05). Conclusion The double-pass OQASTM II can evaluate comparatively completely and objectively the optical quality of patients with amblyopia,which can provide objective basis for clinical diagnosis for patients with amblyopia.
Objective To compare the objective optical quality between monocular amblyopia eye and the eyes without amblyopia by means of double-pass optical quality analysis system( OQASTM II). Methods Twenty-eight patients with monocular amblyopia( both eyes) were examined by double-pass OQASTM II,the parameters including modulation transfer function cutoff frequency( MTFcut off),Strehl ratio( SR),objective scatter index( OSI),visual acuity( VA) in contrast degree of 100%,20%,9%,respectively,were detected and analyzed,moreover,the differences between two eyes and the causes were analyzed. Results There was no significant difference in DSI value between non-amblyopia eye and amblyopia eye( P > 0. 05). However there were significant differences in MTF cut off,SR value between non-amblyopia eye and amblyopia eye( P < 0. 05),moreover,there was significant difference in VA value in contrast degree of 100%,20%,9%,respectively between non-amblyopia eye and amblyopia eye( P < 0. 05),Besides binocular vision was not correlated to patient's age,optimized corrected vision and equivalent spherical lens( P > 0. 05). Conclusion The double-pass OQASTM II can evaluate comparatively completely and objectively the optical quality of patients with amblyopia,which can provide objective basis for clinical diagnosis for patients with amblyopia.
引文
1 Saad A,Saab M,Gatinel D.Repeatability of measurements with a double-pass system.J Cataract Refract Surg,2010,36:28-33.
2 Artal P,Ferro M,Miranda I,et al.Effects of aging in retinal image quality.J Opt Soc Am A,1993,10:1656-1662.
3 Guirao A,Gonzalez C,Redondo M,et al.Average optical performance of the human eye as a function of age in a normal population.Invest Ophthalmol Vis Sci,1999,40:203-213.
4 Santamaria J,Artal P,Bescos J.Determination of the point spread function of human eyes using a hybrid optical-digital method.J Opt Soc Am A,1987,4:1109-1114.
5 Charman WN.Wavefront technology:past,present and future.Contlens Anterior Eye,2005,28:75-92.
6 万修华,张烨,乔利亚.双通道系统视觉质量分析仪评价正常人视觉质量的可重复性研究.眼科,2013,22:175-179.
7 肖显文,张红,田芳.双通道视觉质量分析系统在眼科的应用.国际眼科纵览,2013,37:77-82.
8 姜珺,金婉卿,吕帆.点扩散函数法在人眼成像质量分析中的特征.眼视光学杂志,2008,4:291-294.
9 Weakley DR.The association between nonstrabismic anisometropia,amblyopia,and subnormal binocularity.Ophthalmol,2001,108:163-17.
10 Vilaseca M,Peris E,Pujol J,et al.Intra-and intersession repeatability of a double-pass instrument.Optom Vis Sci.2010,87:675-681.
11 蔡啸谷,乔利亚,张烨,等.双通道视觉质量分析系统可靠性评价及相关影响因素分析.眼科新进展,2013,7:646-650.
12 Martínez-Roda JA,Vilaseca M,Ondategui JC,et al.Optical quality and intraocular scattering in a healthy young population.Clin Exp Optom,2011,94:223-229.
13 Tomas J,Pinero DP,Alio JL.Intra-observer repeatability of optical quality measures provided by a double-pass system.Clin Exp Optom,2012,95:60-65.
14 Vilaseca M,Romero MJ,Arjona M,et al.Grading nuclear,cortical and posterior subcapsular cataracts using an objective scatter index measured with a double-pass system.Br J Ophthalmol,2012,96:1204-1210.
15 Ondategui JC,Vilaseca M,Arjona M.Optical quality after myopic photorefractive keratectomy and laser in situ keratomileusis:comparison using a double-pass system.J Cataract Refract Surg,2012,38:16-27.
16 Vilaseca M,Padilla A,Pujol J.Optical quality one month after verisyse and Veriflex phakic IOL implantation and Zeiss MEL 80 LASIK for myopia from 5.00 to 16.50 diopters.J Refract Surg,2009,25:689-698.
17 Jimenez JR,Ortiz C,Perez-Ocon F.Optical image quality and visual performance for patients with keratitis.Cornea,2009.783-788.
18 Nanavaty MA,Stanford MR,Sharma R,et al.Use of the double-pass technique to quantify ocular scatter in patients with uveitis:a pilot study.Ophthalmologica,2011,225:61-66.
19 Pujol J,Gispets J,Arjona M.Optical performance in eyes wearing two multifocal contact lens designs.Ophthalmic Physiol Opt,2003,23:347-360.
20 Montes-Mico R,Alio JL,Charman WN.Postblink changes in the ocular modulation transfer function measured by a double-pass method.Invest Ophthalmol Vis Sci,2005,46:4468-4473.
21 Kurian M,Nagappa S,Bhagali R.Visual quality after posterior chamber phakic intraocular lens implantation in keratoconus.J Cataract Refract Surg,2012,38:1050-1057.
22 Kamiya K,Shimizu K,Igarashi A.Clinical evaluation of optical quality and intraocular scattering after posterior chamber phakic intraocular lens implantation.Invest Ophthalmol Vis Sci,2012,53:3161-3166.
23 肖信,刘伟民,王英.双通道视觉质量分析系统评价弱视儿童的视觉质量.眼科新进展,2014,34:1157-1160.
24 徐江姗,王宏伟.儿童弱视治疗研究进展.国际眼科杂志,2013,13:302-305.
25 Thibos LN,Hong X,Bradley A,et al.Accuracy and precision of objective refraction from wavefront aberrati.J Vis,2004,4:329-351.
26 Vilaseca M,Padilla A,Pujol J,et al.Optical quality one month after verisyse and Veriflex phakic IOL implantation and Zeiss MEL 80 LASIK for myopia from 5.00 to 16.50 diopters.J Refract Surg,2009,25:689-698.
2 Artal P,Ferro M,Miranda I,et al.Effects of aging in retinal image quality.J Opt Soc Am A,1993,10:1656-1662.
3 Guirao A,Gonzalez C,Redondo M,et al.Average optical performance of the human eye as a function of age in a normal population.Invest Ophthalmol Vis Sci,1999,40:203-213.
4 Santamaria J,Artal P,Bescos J.Determination of the point spread function of human eyes using a hybrid optical-digital method.J Opt Soc Am A,1987,4:1109-1114.
5 Charman WN.Wavefront technology:past,present and future.Contlens Anterior Eye,2005,28:75-92.
6 万修华,张烨,乔利亚.双通道系统视觉质量分析仪评价正常人视觉质量的可重复性研究.眼科,2013,22:175-179.
7 肖显文,张红,田芳.双通道视觉质量分析系统在眼科的应用.国际眼科纵览,2013,37:77-82.
8 姜珺,金婉卿,吕帆.点扩散函数法在人眼成像质量分析中的特征.眼视光学杂志,2008,4:291-294.
9 Weakley DR.The association between nonstrabismic anisometropia,amblyopia,and subnormal binocularity.Ophthalmol,2001,108:163-17.
10 Vilaseca M,Peris E,Pujol J,et al.Intra-and intersession repeatability of a double-pass instrument.Optom Vis Sci.2010,87:675-681.
11 蔡啸谷,乔利亚,张烨,等.双通道视觉质量分析系统可靠性评价及相关影响因素分析.眼科新进展,2013,7:646-650.
12 Martínez-Roda JA,Vilaseca M,Ondategui JC,et al.Optical quality and intraocular scattering in a healthy young population.Clin Exp Optom,2011,94:223-229.
13 Tomas J,Pinero DP,Alio JL.Intra-observer repeatability of optical quality measures provided by a double-pass system.Clin Exp Optom,2012,95:60-65.
14 Vilaseca M,Romero MJ,Arjona M,et al.Grading nuclear,cortical and posterior subcapsular cataracts using an objective scatter index measured with a double-pass system.Br J Ophthalmol,2012,96:1204-1210.
15 Ondategui JC,Vilaseca M,Arjona M.Optical quality after myopic photorefractive keratectomy and laser in situ keratomileusis:comparison using a double-pass system.J Cataract Refract Surg,2012,38:16-27.
16 Vilaseca M,Padilla A,Pujol J.Optical quality one month after verisyse and Veriflex phakic IOL implantation and Zeiss MEL 80 LASIK for myopia from 5.00 to 16.50 diopters.J Refract Surg,2009,25:689-698.
17 Jimenez JR,Ortiz C,Perez-Ocon F.Optical image quality and visual performance for patients with keratitis.Cornea,2009.783-788.
18 Nanavaty MA,Stanford MR,Sharma R,et al.Use of the double-pass technique to quantify ocular scatter in patients with uveitis:a pilot study.Ophthalmologica,2011,225:61-66.
19 Pujol J,Gispets J,Arjona M.Optical performance in eyes wearing two multifocal contact lens designs.Ophthalmic Physiol Opt,2003,23:347-360.
20 Montes-Mico R,Alio JL,Charman WN.Postblink changes in the ocular modulation transfer function measured by a double-pass method.Invest Ophthalmol Vis Sci,2005,46:4468-4473.
21 Kurian M,Nagappa S,Bhagali R.Visual quality after posterior chamber phakic intraocular lens implantation in keratoconus.J Cataract Refract Surg,2012,38:1050-1057.
22 Kamiya K,Shimizu K,Igarashi A.Clinical evaluation of optical quality and intraocular scattering after posterior chamber phakic intraocular lens implantation.Invest Ophthalmol Vis Sci,2012,53:3161-3166.
23 肖信,刘伟民,王英.双通道视觉质量分析系统评价弱视儿童的视觉质量.眼科新进展,2014,34:1157-1160.
24 徐江姗,王宏伟.儿童弱视治疗研究进展.国际眼科杂志,2013,13:302-305.
25 Thibos LN,Hong X,Bradley A,et al.Accuracy and precision of objective refraction from wavefront aberrati.J Vis,2004,4:329-351.
26 Vilaseca M,Padilla A,Pujol J,et al.Optical quality one month after verisyse and Veriflex phakic IOL implantation and Zeiss MEL 80 LASIK for myopia from 5.00 to 16.50 diopters.J Refract Surg,2009,25:689-698.