美托洛尔(倍他乐克)与他汀类药联合治疗心肌梗死的临床效果观察
摘要
目的:探讨美托洛尔(倍他乐克)与他汀类药联合治疗心肌梗死的临床疗效。方法:根据随机数字表法进行2017年4月-2018年2月90例心肌梗死患者分成两组。对照组给予美托洛尔(倍他乐克)治疗,观察组则给予美托洛尔(倍他乐克)联合他汀类药治疗。比较两组心肌梗死治疗转归效果;治疗后心率和总胆固醇水平;治疗前后患者心功能检查指标;用药安全特点。结果:观察组心肌梗死治疗转归效果高于对照组,差异有统计学意义(P<0.05);观察组治疗后心率和总胆固醇水平优于对照组,差异有统计学意义(P<0.05);治疗前两组心功能检查指标比较差异无统计学意义(P>0.05);治疗后观察组心功能检查指标优于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较差异无统计学意义(P>0.05)。结论:美托洛尔(倍他乐克)联合他汀类药治疗心肌梗死的疗效确切,可有效改善心功能,降低胆固醇水平,改善心率,无严重副作用,值得推广应用。
引文
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[9]曹俊杰.美托洛尔与他汀类药联合治疗心肌梗死临床疗效观察[J].深圳中西医结合杂志,2016,26(14):159-160.
[10]冯忠,张大锐,钟巧燕,等.加味丹参饮对老年轻、中度高心功能,胆固醇和心率等指标伴心肌梗死患者心肌功能的保护作用观察[J].湖南中医药大学学报,2018(5):578-581.
[11]Gemmati D,Zeri G,Orioli E,et al.FactorⅧ-A dynamics in acute myocardial infarction:a novel prognostic biomarker?[J].Thrombosis and Haemostasis:Journal of the International Society on Thrombosis and Haemostasis,2015,114(1):123-132.
[12]刘秀红.美托洛尔与他汀类药联合治疗心肌梗死的疗效评价[J].中国医药指南,2017,15(15):114.
[2]Ji M S,Jeong M H,Ahn Y K,et al.Impact of low level of high-density lipoprotein-cholesterol sampled in overnight fasting state on the clinical outcomes in patients with acute myocardial infarction(difference between ST-segment and non-ST-segment-elevation myocardial infarction)[J].Journal of Cardiology,2015,65(1/2):63-70.
[3]周朝伟.阿托伐他汀联合美托洛尔治疗冠心病合并高脂血症的效果观察[J].临床医学工程,2018(5):585-586.
[4]Luo K Q,Long H B,Xu B C,et al.Reduced Apoptosis After Acute Myocardial Infarction by Simvastatin[J].Cell Biochemistry and Biophysics,2015,71(2):735-740.
[5]薛晓芳.美托洛尔(倍他乐克)与他汀类药联合治疗心肌梗死患者的临床疗效比较[J/OL].中西医结合心血管病电子杂志,2017,5(25):43,46.
[6]姚红.美托洛尔与他汀类药联合治疗心肌梗死的疗效分析[J].中国继续医学教育,2017,9(16):168-169.
[7]Mohamed M,Andrzej S K,Sana M A,et al.Implications of ventricular arrhythmia“bursts”with normal epicardial flow,myocardial blush,and ST-segment recovery in anterior ST-elevation myocardial infarction reperfusion:A biosignature of direct myocellular injury“downstream of downstream”[J].European Heart Journal,2015,4(1):51-59.
[8]王伟明,韩福建,邱洪兵,等.美托洛尔(倍他乐克)与他汀类药联合治疗心肌梗死的临床疗效分析[J].北方药学,2017,14(1):44-45.
[9]曹俊杰.美托洛尔与他汀类药联合治疗心肌梗死临床疗效观察[J].深圳中西医结合杂志,2016,26(14):159-160.
[10]冯忠,张大锐,钟巧燕,等.加味丹参饮对老年轻、中度高心功能,胆固醇和心率等指标伴心肌梗死患者心肌功能的保护作用观察[J].湖南中医药大学学报,2018(5):578-581.
[11]Gemmati D,Zeri G,Orioli E,et al.FactorⅧ-A dynamics in acute myocardial infarction:a novel prognostic biomarker?[J].Thrombosis and Haemostasis:Journal of the International Society on Thrombosis and Haemostasis,2015,114(1):123-132.
[12]刘秀红.美托洛尔与他汀类药联合治疗心肌梗死的疗效评价[J].中国医药指南,2017,15(15):114.