0～6岁儿童全血微量元素含量回顾性分析
|
摘要
目的分析石家庄0～6岁儿童全血中铁、锌、钙、镁微量元素水平。方法选取2016年1月至2017年12月于石家庄市妇幼保健院儿童保健门诊体检的0～6岁儿童2 318人,通过静脉采血进行铁、锌、钙、镁微量元素检测,分析不同年龄段微量元素含量。结果不同年龄段均有不同程度的微量元素缺乏,钙离子缺乏率占30.41%,其中4～5岁儿童组钙离子缺乏率最高,组间均数比较差异有统计学意义(P<0.05)。铁离子缺乏率9.75%,其中3～4岁儿童组铁离子缺乏率最高,组间均数比较差异有统计学意义(P<0.05)。镁离子缺乏率5.69%,其中3～4岁儿童组镁离子缺乏率最高,组间均数比较差异有统计学意义(P<0.05)。锌元素缺乏率3.67%,其中3～4岁儿童组锌元素缺乏率最高,组间均数比较差异有统计学意义(P<0.05)。结论各年龄段儿童全血中微量元素均有缺乏,通过开展儿童保健工作及儿童微量元素检测可较全面有效了解0～6岁儿童的微量元素缺乏情况,并有针对性给予指导补充改善,有利于儿童生长发育。
Objective To analyze the trace element contents, including iron, zinc, calcium and magnesium, in the whole blood of children aged 0～6 years in Shijiazhuang.Methods A total of 2318 children aged 0～6 years who underwent physical examination in the Child Health Clinic of Shijiazhuang Hospital for Maternal and Child Health from January 2016 to December 2017 were selected for the determination of trace elements, including iron, zinc, calcium and magnesium by collecting venous blood sample. Trace element contents in different age groups was analyzed.Results There were different levels of trace element deficiency in different age groups, and the calcium ion deficiency rate accounted for 30.41%. Among them, the calcium ion deficiency rate was the highest in children aged 4～5 years, and the difference between the groups was statistically significant(P<0.05). The iron ion deficiency rate was 9.75%, and the deficiency rate was the highest among the children aged 3 to 4 years. The difference between the groups was statistically significant(P<0.05). The magnesium ion deficiency rate was 5.69%, and the deficiency rate was the highest in the children aged 3～4 years. The difference between the groups was statistically significant(P<0.05). The zinc deficiency rate was 3.67%, and the deficiency rate was the highest among the children aged 3 to 4 years. The difference between the groups was statistically significant(P<0.05).Conclusion Trace elements are found to be deficient in whole blood of children of all ages. By implementation of child health work and determination of trace elements in children, we can comprehensively and effectively understand deficiency of trace elements in children aged 0～6 years, and provide targeted guidance for improvement. This exhibits beneficial effects on growth and development of children.
Objective To analyze the trace element contents, including iron, zinc, calcium and magnesium, in the whole blood of children aged 0～6 years in Shijiazhuang.Methods A total of 2318 children aged 0～6 years who underwent physical examination in the Child Health Clinic of Shijiazhuang Hospital for Maternal and Child Health from January 2016 to December 2017 were selected for the determination of trace elements, including iron, zinc, calcium and magnesium by collecting venous blood sample. Trace element contents in different age groups was analyzed.Results There were different levels of trace element deficiency in different age groups, and the calcium ion deficiency rate accounted for 30.41%. Among them, the calcium ion deficiency rate was the highest in children aged 4～5 years, and the difference between the groups was statistically significant(P<0.05). The iron ion deficiency rate was 9.75%, and the deficiency rate was the highest among the children aged 3 to 4 years. The difference between the groups was statistically significant(P<0.05). The magnesium ion deficiency rate was 5.69%, and the deficiency rate was the highest in the children aged 3～4 years. The difference between the groups was statistically significant(P<0.05). The zinc deficiency rate was 3.67%, and the deficiency rate was the highest among the children aged 3 to 4 years. The difference between the groups was statistically significant(P<0.05).Conclusion Trace elements are found to be deficient in whole blood of children of all ages. By implementation of child health work and determination of trace elements in children, we can comprehensively and effectively understand deficiency of trace elements in children aged 0～6 years, and provide targeted guidance for improvement. This exhibits beneficial effects on growth and development of children.
引文
1 World Health Organization.全民健康覆盖研究.2013.
2 杨思嘉.675名中小学生发样中六种矿物质元素含量与生长发育状况的相关性分析.吉林大学,2013.
3 曲文超,魏本荣,赵治远.0-6岁儿童血中微量元素含量分析.临床医药文献杂志,2018,5:110-112.
4 中华人民共和国国家卫生和计划生育委员会.WS/T476-2015营养名词术语.2015-12-29.
5 刘小兵.2002、2012年中国农村儿童血浆/血清16种微量元素含量分析及锌营养状况评估.中国疾病预防控制中心,2014.
6 张少雨,刘寅.儿童微量元素水平与疾病发生的关系.临床医学研究与实践,2016,1:128.
7 范芳,钱新宏,潘凯丽,等.微量元素铁、锌联合红细胞4项参数在小儿缺铁性贫血中的诊断价值.国际检验医学杂志,2015,36:998-1000.
8 Saraiva BC,Soares MC,Santos LC,et al.Iron deficiency and anemia are associated with low retinol levels in children aged 1 to 5 years.J Pediatr (Rio J),2014,90:593-599.
9 中国0-6岁儿童营养发展报告(节录).营养学报,2013.1-4.
10 Yan Y,Li Y,Qin L,et al.Evaluation of the Relationship Between Height and Zinc,Copper,Iron,Calcium,and Magnesium Levels in Healthy Young Children in Beijing,Chian.Biological Trace Element Research,2016:1-7.
11 黄影.分析儿童钙营养不良影响骨健康发育的临床诊疗.临床医药文献电子杂志,2015,16:3217.
12 于野.儿童钙、铁和锌缺乏对儿童生长发育的影响.世界最新医学信息文摘,2016,16:67-69.
13 赵惠君.关注儿童铁缺乏症的有效防治.临床儿科杂志,2015,33:405-407.
14 海陵.儿童性早熟究竟谁之过.江苏卫生保健,2015,17:50-51.
15 张美玲.缺铁性贫血对儿童生长发育的影响研究.世界最新医学信息文摘,2016,16:38-48.
16 Ozmen H,Akarsu S,Polat F,et al.The Levels of Calcium and Magnesium,and of Selected Trace Elements,in Whole Blood and Scalp Hair of Chidren with Growth Retardation.Iranian Journal of Pediatrics,2013,23:125-130.
17 Azab SF,Saleh SH,Elsaeed WF,et al.Serum trace elements in obese Egyptian children:a case-control study.Italian Journal of Pediatrics,2014,40:1-7.
18 陈亚楠.儿童生长发育状况与血液微量元素浓度的相关性研究.社区医学杂志,2017,15:17-19.
19 张养华.邹城儿童六种元素含量的相关因素分析及小儿常见贫血和六元素关系.山东大学,2013.
20 朱玉红.2010-2013年横塘地区1000例学龄前儿童五种金属元素水平分析.医学理论与实践,2015,28:129-131.
21 庞海云,马志超,付娇,等.海口地区3820例儿童锌缺乏情况分析.中国优生与遗传杂志,2015,23:125-126.
22 康海燕,李婷,赵剑.榆林地区5000例0-12岁儿童全血中5种微量元素的检测与分析.预防医学,2019,1:107-108.
23 Adriani M,Wirjatmadi B.The effect of adding zine to vitamin A on IGF-1,bone age and linear growth in stunted children.Journal of Trace Elements in Medicin&Biology,2014,28:121-133.
24 张力夫,郭承吉,张敏,等.610例厌食或生长发育不良小儿锌营养状况的研究.中国医科大学学报,1989,18:222-224.
2 杨思嘉.675名中小学生发样中六种矿物质元素含量与生长发育状况的相关性分析.吉林大学,2013.
3 曲文超,魏本荣,赵治远.0-6岁儿童血中微量元素含量分析.临床医药文献杂志,2018,5:110-112.
4 中华人民共和国国家卫生和计划生育委员会.WS/T476-2015营养名词术语.2015-12-29.
5 刘小兵.2002、2012年中国农村儿童血浆/血清16种微量元素含量分析及锌营养状况评估.中国疾病预防控制中心,2014.
6 张少雨,刘寅.儿童微量元素水平与疾病发生的关系.临床医学研究与实践,2016,1:128.
7 范芳,钱新宏,潘凯丽,等.微量元素铁、锌联合红细胞4项参数在小儿缺铁性贫血中的诊断价值.国际检验医学杂志,2015,36:998-1000.
8 Saraiva BC,Soares MC,Santos LC,et al.Iron deficiency and anemia are associated with low retinol levels in children aged 1 to 5 years.J Pediatr (Rio J),2014,90:593-599.
9 中国0-6岁儿童营养发展报告(节录).营养学报,2013.1-4.
10 Yan Y,Li Y,Qin L,et al.Evaluation of the Relationship Between Height and Zinc,Copper,Iron,Calcium,and Magnesium Levels in Healthy Young Children in Beijing,Chian.Biological Trace Element Research,2016:1-7.
11 黄影.分析儿童钙营养不良影响骨健康发育的临床诊疗.临床医药文献电子杂志,2015,16:3217.
12 于野.儿童钙、铁和锌缺乏对儿童生长发育的影响.世界最新医学信息文摘,2016,16:67-69.
13 赵惠君.关注儿童铁缺乏症的有效防治.临床儿科杂志,2015,33:405-407.
14 海陵.儿童性早熟究竟谁之过.江苏卫生保健,2015,17:50-51.
15 张美玲.缺铁性贫血对儿童生长发育的影响研究.世界最新医学信息文摘,2016,16:38-48.
16 Ozmen H,Akarsu S,Polat F,et al.The Levels of Calcium and Magnesium,and of Selected Trace Elements,in Whole Blood and Scalp Hair of Chidren with Growth Retardation.Iranian Journal of Pediatrics,2013,23:125-130.
17 Azab SF,Saleh SH,Elsaeed WF,et al.Serum trace elements in obese Egyptian children:a case-control study.Italian Journal of Pediatrics,2014,40:1-7.
18 陈亚楠.儿童生长发育状况与血液微量元素浓度的相关性研究.社区医学杂志,2017,15:17-19.
19 张养华.邹城儿童六种元素含量的相关因素分析及小儿常见贫血和六元素关系.山东大学,2013.
20 朱玉红.2010-2013年横塘地区1000例学龄前儿童五种金属元素水平分析.医学理论与实践,2015,28:129-131.
21 庞海云,马志超,付娇,等.海口地区3820例儿童锌缺乏情况分析.中国优生与遗传杂志,2015,23:125-126.
22 康海燕,李婷,赵剑.榆林地区5000例0-12岁儿童全血中5种微量元素的检测与分析.预防医学,2019,1:107-108.
23 Adriani M,Wirjatmadi B.The effect of adding zine to vitamin A on IGF-1,bone age and linear growth in stunted children.Journal of Trace Elements in Medicin&Biology,2014,28:121-133.
24 张力夫,郭承吉,张敏,等.610例厌食或生长发育不良小儿锌营养状况的研究.中国医科大学学报,1989,18:222-224.