啄治法联合百蕊颗粒治疗慢性扁桃体炎临床观察
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摘要
目的观察啄治法联合百蕊颗粒治疗慢性扁桃体炎的临床疗效。方法选自2017年1月—2018年6月在本院就诊的116例慢性扁桃体炎患者,按照随机数表法分为治疗组和对照组。治疗组66例,采取啄治法和口服百蕊颗粒,3～4 d行1次啄治法,每天服用3次百蕊颗粒,每次5g。对照组50例,单纯使用啄治法,措施与治疗组相同。7d为1个疗程,两组均治疗2个疗程。结果治疗组总有效率为93.9%,对照组总有效率为92.0%,两组差异不显著(P>0.05);治疗组显效率为80.3%,对照组显效率为68.0%,治疗组优于对照组,差异显著(P<0.05)。治疗组症状和体征评分的改善幅度明显优于对照组(P<0.05)。结论啄治法可以消肿散瘀,百蕊颗粒可以清热抗炎,两者联用治疗慢性扁桃体炎显效率提高,患者症状和体征明显改善。
Objective To observe the curative effect of tonsil-pecking method combined with Bairui Granules for the treatment of chronic tonsillitis. Methods A total of 116 patients with chronic tonsillitis treated in Qinhuangdao City Chinese Medicine Hospital from January 2017 to June 2018 were randomly divided into the treatment group and the control group according to the random number table method. Sixty-six cases in the treatment group were treated with tonsil-pecking method combined with Bairui Granules, tonsil-pecking method once 3 d, Bairui Granules one bag(5 g) three times daily. Fifty cases in the control group were only received tonsil-pecking method. One course was 7 d, both groups were treated for two courses. Result The total effective rate of the treatment group was 93.9%, which of the control group was 92.0%, there was no significant difference in the efficacy between the two groups(P > 0.05). But the significant effective rates of the treatment group was 80.3%, which of the control group was 68.0%, there was a significant difference between the two groups(P < 0.05). And the improvement in symptom and physical signs of the treatment group was significantly better than the cntrol group(P < 0.05). Conclusion Tonsil-pecking method can disperse swelling and stasis. Bairui Granules have antipyretic and antiphlogistic effect, combination administration had higher cure rate in the treatment of chronic tonsillitis, symptoms and signs were improved significantly.
Objective To observe the curative effect of tonsil-pecking method combined with Bairui Granules for the treatment of chronic tonsillitis. Methods A total of 116 patients with chronic tonsillitis treated in Qinhuangdao City Chinese Medicine Hospital from January 2017 to June 2018 were randomly divided into the treatment group and the control group according to the random number table method. Sixty-six cases in the treatment group were treated with tonsil-pecking method combined with Bairui Granules, tonsil-pecking method once 3 d, Bairui Granules one bag(5 g) three times daily. Fifty cases in the control group were only received tonsil-pecking method. One course was 7 d, both groups were treated for two courses. Result The total effective rate of the treatment group was 93.9%, which of the control group was 92.0%, there was no significant difference in the efficacy between the two groups(P > 0.05). But the significant effective rates of the treatment group was 80.3%, which of the control group was 68.0%, there was a significant difference between the two groups(P < 0.05). And the improvement in symptom and physical signs of the treatment group was significantly better than the cntrol group(P < 0.05). Conclusion Tonsil-pecking method can disperse swelling and stasis. Bairui Granules have antipyretic and antiphlogistic effect, combination administration had higher cure rate in the treatment of chronic tonsillitis, symptoms and signs were improved significantly.
引文
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[2]Kania R E,Lamers G E,Vonk M J,et al.Demonstration of bacterial cells and glycocalyx in biofilms on human tonsils[J].Arch Otolaryngol Head Neck Surg,2007,133(2):115-121.
[3]汪冰.啄治法治疗慢性扁桃体炎的临床研究[J].山东中医杂志,2005,24(2):85-87.
[4]刘永松,潘玲,祁克宗,等.百蕊草有效提取成分对七种细菌的敏感性试验[J].贵州医药,2006,30(6):564-566.
[5]王海娣,杜冠华,刘艾林.天然黄酮类化合物的神经氨酸酶抑制活性评价[J].中国新药杂志,2009,18(15):1435-1439.
[6]姜泗长.耳鼻咽喉-头颈外科诊断与鉴别诊断[M].北京:中国协和医科大学出版社,2001.
[7]中药新药临床研究指导原则(第3辑)[S].1997.
[8]侯娜.啄治法治疗慢性扁桃体炎的临床研究[D].济南:山东中医药大学,2004.
[9]彭耀.百蕊胶囊治疗急性咽炎临床疗效观察[J].中医药临床杂志,2007,19(3):273-274.
[10]钱备.百蕊片治疗慢性咽喉炎102例体会[J].安徽医药,2009,13(9):1110-1112.