基于实时直接分析串联高分辨质谱的红色印泥油种类鉴别
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摘要
目的建立红色印泥印油的快速无损分析方法,实现不同种类印泥印油的快速鉴别。方法应用实时直接分析-高分辨质谱(DART-HRMS)技术,对67个不同品牌不同种类的红色印泥印油进行直接无损分析,获取质谱信息。结果采用偏最小二乘判别分析法(PLS-DA)及系统聚类法(HCA)对红色印油印泥进行了分类,依据高分辨质谱信息及标准物对照实现印泥印油中颜料红21、罗丹明B、聚丙烯醇和聚乙二醇类物质的快速定性分析,进一步完成了不同种类印泥印油的区分。结论本研究建立的区分方法快速、无损、准确、无需样品前处理,为物证鉴定工作中印泥印油种类的鉴别提供了依据。
Abstact: Objectve To establish a fast and non-destructive method for the analysis of red seal ink. Method 67 different brands and types of red seal ink were analyzed by direct analysis in real time and Q-Exactive high resolution mass spectrometry(DART-QE). Results A preliminary classification of red seal ink can be carried out acroding to the method of partial least squares discrimination analysis(PLS-DA) and hierarchical Cluster Analysis(HCA), and pigment red 21,rhodamine B,polypropylene glycol and polyethylene glycol can be detected by DART-QE which helps to further distinguish seal ink samples. Conclusion The established method is fast, non-destructive, accurate, and reguries no pre-sample processing. It can be applied in forensic practice for the discrimination of red seal ink.
Abstact: Objectve To establish a fast and non-destructive method for the analysis of red seal ink. Method 67 different brands and types of red seal ink were analyzed by direct analysis in real time and Q-Exactive high resolution mass spectrometry(DART-QE). Results A preliminary classification of red seal ink can be carried out acroding to the method of partial least squares discrimination analysis(PLS-DA) and hierarchical Cluster Analysis(HCA), and pigment red 21,rhodamine B,polypropylene glycol and polyethylene glycol can be detected by DART-QE which helps to further distinguish seal ink samples. Conclusion The established method is fast, non-destructive, accurate, and reguries no pre-sample processing. It can be applied in forensic practice for the discrimination of red seal ink.
引文
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[2]施少培,杨旭,钱煌贵,等.印文鉴定相关问题探讨——高仿真印文鉴定[J].中国司法鉴定,2008,(3):20-23.
[3]王淳浩,王彦吉,张振宇,等.高效液相色谱法鉴别红色原子印油的种类及主要成分的确认[J].中国人民公安大学学报(自然科学版),2006,(1):1-4.
[4]章晴,邹积鑫,石高军,等.超高效液相色谱-质谱联用法与气相色谱-质谱联用法分析水性印油印记的主要成分[J].色谱,2010,(12):1132-1136.
[5]常川.液质联用技术在色痕分析中的应用[D].湖北:华中师范大学,2012.
[6]谢朋,冯超,李彪,等.气相色谱法测定自含墨印章印文的盖印时间[J].中国人民公安大学学报(自然科学版),2013,(02):19-23.
[7]张凌燕,潘自勤,祁堃,等.薄层色谱法鉴定原子印油印文盖印形成时间[J].分析仪器,2012,(1):58-62.
[8]张玉省,黄建同,韩伟.薄层色谱扫描法分析印油印迹成分中印迹浓度的影响[J].湖北警官学院学报,2015,(3):139-141.
[9]韩伟,黄建同,苏乐,等.基于激光显微拉曼技术鉴别印章盖印时间[J].光散射学报,2015,(4):359-363.
[10]Cody Robert B,Laramée James A,Durst H Dupont.Versatile New ion Source for the Analysis of Materials in Open air Under Ambient Conditions[J].Analytical Chemistry,2005,77(8):.
[11]程显隆,李文杰,李卫健,等.DART-MS/MS法直接实时检测保健食品中非法添加的6个PDE5抑制剂的应用研究[J].药物分析杂志,2011,(3):438-442.
[12]李文杰,程显隆,李卫健,等.DART-MS/MS法快速直接分析减肥保健品中非法添加的盐酸西布曲明[J].中国药事,2012,(2):147-149.
[13]张伟,王雪,秦建平,等.DART-Q-TOF-MS快速鉴别桂枝茯苓胶囊中6种化学成分[J].中国中药杂志,2014,(21):4118-4122.
[14]曾珊珊.实时直接分析质谱在中药质量控制中的应用基础研究[D].浙江:浙江大学,2013.
[15]王铁松,张喆,赵明,等.直接实时分析质谱超速分析在药品监管中的应用[J].中国药学杂志,2011,(9):699-703.
[16]张瑛,张文芳,张炜,等.DART-MS在毒物毒品分析中的应用[J].分析试验室,2017,(4):493-496.