麻黄附子甘草汤同时煎煮的减毒效果观察
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摘要
目的研究麻黄附子甘草汤同时煎煮的减毒效果。方法将麻黄、附子、甘草等中药按照不同组合进行配伍煎煮,对比分析不同配伍方式中总生物碱、酯型生物碱及非酯型生物碱的含量,并总结其减毒效果。结果附子单剂中酯型生物碱的含量占总生物碱的39.34%,麻黄与附子组合配方占11.23%,甘草与附子组合配方占10.45%,麻黄、甘草与附子组合配方占8.76%,相较于附子单剂,经过配伍后得到的酯型生物碱含量明显下降,非酯型生物碱含量升高。结论将麻黄与附子、甘草与附子配伍后可降低附子的毒性,而将三者同时煎煮时监督效果更好,值得中药配伍使用。
Objective To study the aconite and Glycyrrhiza Decoction and decoction of the attenuated effect.Methods:Ephedra,aconite root,licorice and other traditional Chinese medicines according to different combinations of decoction combination,comparative analysis of the content of total alkaloids,diester alkaloids and non ester type alkaloids in different compatibility,and summarize the effect of attenuation.Results:Aconite single agent ester type alkaloids content accounted for 39.34%of total alkaloids,ephedra and Fuzi combined formula 11.23%),liquorice and Radix Aconiti Lateralis Preparata combination formula(10.45%,ephedra,licorice and Fuzi combined formula for 8.76%,compared to Fuzi agent,obtained by the compatibility of ester type alkaloids content decreased significantly,non ester type alkaloids increased.Conclusion:Ephedra and aconite root,licorice and aconite can reduce Fuzi toxic,and three at the same time when boiling supervision effect is better,is worthy of Chinese herbal medicines.
Objective To study the aconite and Glycyrrhiza Decoction and decoction of the attenuated effect.Methods:Ephedra,aconite root,licorice and other traditional Chinese medicines according to different combinations of decoction combination,comparative analysis of the content of total alkaloids,diester alkaloids and non ester type alkaloids in different compatibility,and summarize the effect of attenuation.Results:Aconite single agent ester type alkaloids content accounted for 39.34%of total alkaloids,ephedra and Fuzi combined formula 11.23%),liquorice and Radix Aconiti Lateralis Preparata combination formula(10.45%,ephedra,licorice and Fuzi combined formula for 8.76%,compared to Fuzi agent,obtained by the compatibility of ester type alkaloids content decreased significantly,non ester type alkaloids increased.Conclusion:Ephedra and aconite root,licorice and aconite can reduce Fuzi toxic,and three at the same time when boiling supervision effect is better,is worthy of Chinese herbal medicines.
引文
[1]钟梅芳.麻黄附子甘草汤的不同配伍方式对其毒性成分的影响分析[J].实用中医内科杂志,2012,26(7).
[2]刘险峰.麻黄附子甘草汤同时煎煮的减毒效果观察[J].转化医学电子杂志,2015,2(2):35-36.
[3]闫宗敬.麻黄附子甘草汤同时煎煮减毒效果观察[J].转化医学电子杂志,2014,1(4):44-45.
[4]戴琳.麻黄附子甘草汤同时煎煮的减毒效果观察[J].中国保健营养(下旬刊),2014,24(4):2323-2324.
[5]李华,李志强.麻黄附子甘草汤同时煎煮减毒效果观察[J].中国保健营养(下旬刊),2014,24(2):1131.
[2]刘险峰.麻黄附子甘草汤同时煎煮的减毒效果观察[J].转化医学电子杂志,2015,2(2):35-36.
[3]闫宗敬.麻黄附子甘草汤同时煎煮减毒效果观察[J].转化医学电子杂志,2014,1(4):44-45.
[4]戴琳.麻黄附子甘草汤同时煎煮的减毒效果观察[J].中国保健营养(下旬刊),2014,24(4):2323-2324.
[5]李华,李志强.麻黄附子甘草汤同时煎煮减毒效果观察[J].中国保健营养(下旬刊),2014,24(2):1131.