中西医结合治疗颌面部慢性化脓性炎症临床观察
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摘要
目的:探讨中西医结合治疗颌面部慢性化脓性炎症的临床效果。方法:颌面部慢性化脓性炎症患者共52例,按照随机数字的方法分为两组,对照组和观察组,每组26例,对照组使用西医治疗方法,观察组在对照组治疗方法基础上使用中药联合治疗,对治疗的效果进行分析。结果:对照组中痊愈10例,显效11例,无效5例,观察组中痊愈14例,显效12例,无效0例,观察组的治疗效果优于对照组患者,数据差异具有统计学意义(z=-6.343,P<0.05),对照组痊愈的时间为(10.27±1.83)d,显效的时间为(9.84±1.41)d,观察组痊愈的时间为(8.04±0.98)d,显效的时间为(8.01±0.87)d,观察组的痊愈时间和显效时间均短于对照组,数据差异均具有统计学意义(t=3.869,3.783,P<0.05),经过治疗后,对照组的血清C反应蛋白从(15.22±2.81)mg/L降低为(5.61±0.81)mg/L,白细胞介素-4从(4.42±0.64)ng/L升高为(13.27±3.51)ng/L,白细胞介素-6从(66.71±8.36)ng/L降低为(19.68±3.57)ng/L,肿瘤坏死因子-α从(88.56±6.27)ng/L降低为(50.26±7.28)ng/L,观察组的血清C反应蛋白从(15.31±3.08)mg/L降低为(2.35±0.71)mg/L,白细胞介素-4从(4.56±0.71)ng/L升高为(19.57±4.44)ng/L,白细胞介素-6从(67.51±7.61)ng/L降低为(11.85±2.81)ng/L,肿瘤坏死因子-α从(89.71±5.94)ng/L降低为(23.47±4.64)ng/L,观察组各类血清炎性因子改善的幅度均优于对照组,数据差异均具有统计学意义(t=15.433,-5.676,8.788,15.823,P<0.05)。结论:使用中西医结合的方法治疗颌面部慢性化脓性炎症患者,可以提升治疗效果,缩短恢复时间。
Objective:To explore the clinical effect of integrated traditional Chinese and Western medicine in treating chronic suppurative inflammation in maxillofacial region. Methods:52 patients with chronic suppurative inflammation of the maxillofacial region with. According to the random number method, 52 patients with were divided into the control group and the observation group, with 26 patients in each group. The patients in the control group were treated with Western medicine, and those in the observation group were treated with traditional Chinese medicine on the basis of the treatment methods of the control group, and the effect of the treatment was analyzed. Result:In the control group, 10 patients were cured, 11 markedly effective, 5 invalid and 14 patients in the observation group were cured, 12 markedly effective and 0 invalid. The treatment effect of the observation group was better than that of the control group, and the difference was statistically significant(z=-6.343, P<0.05). The cure time of the control group was(10.27±1.83) d, and the effective time was(9.84±1.41) d. The recovery time of the observation group was(8.04±0.98) d, and the effective time was(8.01±0.87) d. The recovery time and effective time of the observation group were shorter than those of the control group, and the difference was statistically significant(t=3.869, 3.783, P<0.05). After treatment, the serum C reactive protein of the control group decreased from(15.22±2.81) mg/L to(5.61±0.81) mg/L, and interleukin-4 increased from(4.42±0.64) ng/L to(13.27±3.51) ng/L, and interleukin-6 decreased from(66.71±8.36) ng/L to(19.68±3.57) ng/L, tumor necrosis factor-α decreased from(8.56±6.27) ng/L to(50.26±7.28) ng/L. The serum C reactive protein of the patients in the observation group decreased from(15.31±3.08) mg/L to(2.35±0.71) mg/L, interleukin-4 increased from(4.56±0.71) ng/L to(19.57±4.44) ng/L, and interleukin-6 decreased from(67.51±7.61) ng/L to(11.85±2.81) ng/L, and TNF-α decreased from(89.71±5.94) ng/L to(23.47±4.64) ng/L. The improvement of all kinds of serum inflammatory factors in the observation group was better than those of the control group, and the difference of the data was statistically significant(t=15.433,-5.676, 8.788, 15.823, P<0.05). Conclusion:The treatment of chronic suppurative inflammation in the maxillofacial region by combination of traditional Chinese and Western medicine can improve the therapeutic effect and shorten the recovery time.
Objective:To explore the clinical effect of integrated traditional Chinese and Western medicine in treating chronic suppurative inflammation in maxillofacial region. Methods:52 patients with chronic suppurative inflammation of the maxillofacial region with. According to the random number method, 52 patients with were divided into the control group and the observation group, with 26 patients in each group. The patients in the control group were treated with Western medicine, and those in the observation group were treated with traditional Chinese medicine on the basis of the treatment methods of the control group, and the effect of the treatment was analyzed. Result:In the control group, 10 patients were cured, 11 markedly effective, 5 invalid and 14 patients in the observation group were cured, 12 markedly effective and 0 invalid. The treatment effect of the observation group was better than that of the control group, and the difference was statistically significant(z=-6.343, P<0.05). The cure time of the control group was(10.27±1.83) d, and the effective time was(9.84±1.41) d. The recovery time of the observation group was(8.04±0.98) d, and the effective time was(8.01±0.87) d. The recovery time and effective time of the observation group were shorter than those of the control group, and the difference was statistically significant(t=3.869, 3.783, P<0.05). After treatment, the serum C reactive protein of the control group decreased from(15.22±2.81) mg/L to(5.61±0.81) mg/L, and interleukin-4 increased from(4.42±0.64) ng/L to(13.27±3.51) ng/L, and interleukin-6 decreased from(66.71±8.36) ng/L to(19.68±3.57) ng/L, tumor necrosis factor-α decreased from(8.56±6.27) ng/L to(50.26±7.28) ng/L. The serum C reactive protein of the patients in the observation group decreased from(15.31±3.08) mg/L to(2.35±0.71) mg/L, interleukin-4 increased from(4.56±0.71) ng/L to(19.57±4.44) ng/L, and interleukin-6 decreased from(67.51±7.61) ng/L to(11.85±2.81) ng/L, and TNF-α decreased from(89.71±5.94) ng/L to(23.47±4.64) ng/L. The improvement of all kinds of serum inflammatory factors in the observation group was better than those of the control group, and the difference of the data was statistically significant(t=15.433,-5.676, 8.788, 15.823, P<0.05). Conclusion:The treatment of chronic suppurative inflammation in the maxillofacial region by combination of traditional Chinese and Western medicine can improve the therapeutic effect and shorten the recovery time.
引文
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[13] 肖晗,孙红,向飞艳,等.武汉地区宫颈感染人乳头瘤病毒患者年龄分布及感染类型特征[J].中国感染控制杂志,2017,16(5):399-403.
[14] 田永福,吴振清,马莉,等.封闭负压吸引配合清创术治疗颌面部感染[J].中华整形外科杂志,2015,31(2):142.
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[19] 曹昆,张智慧,高凡,等.颌面部感染丹毒病1例[J].宁夏医科大学学报,2017,39(4):483-484.
[20] 程志富.267 例口腔颌面部间隙感染的临床分析[J].赤峰学院学报(自然科学版),2015,31(6):77-78.
[21] 胡银徐.老年口腔颌面部间隙感染患者临床特征分析[J].山东医药,2014,54(22):68-69.
[22] 徐金标,孙鑫,魏军水.口腔颌面部间隙感染的诊断及治疗效果评价[J].中华医院感染学杂志,2013,23(8):1832-1834.
[23] 金艳红.中西医结合治疗口腔颌面部间隙感染50 例[J].中医临床研究,2014,6(11):59-60.
[2] 董锋平,弓兰秀.地塞米松联合头孢克肟口周注射对口颌面部感染患者血清免疫球蛋白影响研究[J].中国生化药物杂志,2015(12):84-86.
[3] 宋长广,孔令廷,李爱芹,等.厌氧菌培养在颌面部感染治疗中的意义[J].中华医院感染学杂志,2007,17(8):922-922.
[4] 潘德民.中西医结合治疗颌面部间隙感染疗效观察[J].现代中西医结合杂志,2014(15):1651-1653.
[5] 黄长波,林燕.口腔颌面部感染患者厌氧菌分布及药敏分析[J].国际检验医学杂志,2018,39(2):196-198.
[6] 王启晋.颌面部间隙感染的诊治研究进展[J].中国美容医学,2017,26(12):143-145.
[7] 吴伟,潘凌峰,徐斌,等.口腔颌面部多间隙感染患者住院期间不良结局发生的危险因素分析[J].中国全科医学,2017,20(z1):75-77.
[8] 廖建春.两种方法治疗中重度颌面部间隙感染的效果观察[J].中西医结合心血管病电子杂志,2017,5(28):60.
[9] 王建国,李可来,李庆隆,等.苯扎氯铵溶液与碘伏溶液冲洗治疗颌面部脓肿疗效比较[J].口腔颌面外科杂志,2013,23(4):299-301.
[10] 张富兴.开髓引流术与开髓失活术治疗急性牙髓炎的疗效比较[J].中国医药指南,2014(26):101.
[11] 刘志刚,李慧.口腔颌面部间隙感染患者的临床疗效[J].中国药物经济学,2015,8(11):85-87.
[12] 朱春华,罗世玉.感染可能性评分监测多发性骨髓瘤患者院内血流感染的价值[J].中国老年学杂志,2017,37(19):4872-4873.
[13] 肖晗,孙红,向飞艳,等.武汉地区宫颈感染人乳头瘤病毒患者年龄分布及感染类型特征[J].中国感染控制杂志,2017,16(5):399-403.
[14] 田永福,吴振清,马莉,等.封闭负压吸引配合清创术治疗颌面部感染[J].中华整形外科杂志,2015,31(2):142.
[15] 邓巍,谢洪,孙晓菊,等.重症颌面部多间隙感染并发纵膈脓肿的诊治:附9例分析[J].中国美容整形外科杂志,2014,25(5):304-306.
[16] 王鸿,廖天安,胡广伟,等.口腔颌面部间隙感染108例分析[J].江苏医药,2015,41(2):205-206.
[17] 丁季元.特殊体质患者颌面部感染3例报告[J].临床口腔医学杂志,2007,23(11):703.
[18] 林洋洋,樊丽萍,黄晶晶,等.康复新液促进颌面部感染创口愈合的临床应用[J].中国美容医学,2014,23(12):1017-1018.
[19] 曹昆,张智慧,高凡,等.颌面部感染丹毒病1例[J].宁夏医科大学学报,2017,39(4):483-484.
[20] 程志富.267 例口腔颌面部间隙感染的临床分析[J].赤峰学院学报(自然科学版),2015,31(6):77-78.
[21] 胡银徐.老年口腔颌面部间隙感染患者临床特征分析[J].山东医药,2014,54(22):68-69.
[22] 徐金标,孙鑫,魏军水.口腔颌面部间隙感染的诊断及治疗效果评价[J].中华医院感染学杂志,2013,23(8):1832-1834.
[23] 金艳红.中西医结合治疗口腔颌面部间隙感染50 例[J].中医临床研究,2014,6(11):59-60.