Pentacam和Keratron Scout测量Kappa角的一致性分析
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摘要
目的:探讨Pentacam眼前节分析仪和Keratron Scout角膜地形图仪测量Kappa角的一致性,评价两种仪器测量结果的重复性。方法:前瞻性随机对照研究。选取2018-01-01/30在我院眼视光中心行近视术前检查的患者69例,所有受试者由同一检查者分别采用Pentacam和Keratron Scout重复测量3次,以(X,Y)坐标形式记录Kappa角的大小,采用组内相关系数(ICC)、Cronbach's Alpha系数评价两种仪器测量Kappa角的重复性;t检验比较两种仪器测量结果的差异,Pearson相关分析其相关性;Bland-Altman图评估两种仪器测量结果的一致性。结果:3次重复测量时,两种仪器均表现出很好的重复性,两种仪器测得Kappa角差异无统计学意义(X值:P=0.17;Y值:P=0.61),Pearson相关分析表明Kappa角大小具有相关性(X值:r=0.90,P<0.01;Y值:r=0.91,P<0.01)。Bland-Altman图显示X值和Y值95%一致性区间分别为-0.11～0.14mm和-0.10～0.11mm。结论:Pentacam眼前节分析仪和Keratron Scout角膜地形图仪测量角膜屈光手术患者Kappa角重复性好,两种仪器测量的Kappa角结果一致性好,可以相互验证。
AIM: To investigate the repeatability and agreement of Pentacam Front Section Analyzer and Keratron Scout Corneal Topographer in measuring Kappa angle.METHODS: Totally 69 patients were randomly selected from Ophthalmology Department of Leshan People's Hospital.Three readings were taken by the same examiner.Results were recorded in(X, Y) coordinates format and assessed by intraclass correlation coefficient(ICC), Cronbach's Alpha Coefficient, t-test, Pearson correlation analysis and bland-altman analysis.RESULTS: Both instruments showed excellent repeatability in Kappa angle assessment.The results significantly correlated(X value: r=0.90, P<0.01; Y value: r=0.91, P<0.01), however, no significant difference were found between the two instruments.The widest 95% LoA was-0.11-0.14 mm for X coordinate and-0.10-0.11 mm for Y.CONCLUSION: Pentacam and Keratron Scout showed excellent repeatability and agreement in Kappa angle assessment.The two instruments could aid and verify each other.
AIM: To investigate the repeatability and agreement of Pentacam Front Section Analyzer and Keratron Scout Corneal Topographer in measuring Kappa angle.METHODS: Totally 69 patients were randomly selected from Ophthalmology Department of Leshan People's Hospital.Three readings were taken by the same examiner.Results were recorded in(X, Y) coordinates format and assessed by intraclass correlation coefficient(ICC), Cronbach's Alpha Coefficient, t-test, Pearson correlation analysis and bland-altman analysis.RESULTS: Both instruments showed excellent repeatability in Kappa angle assessment.The results significantly correlated(X value: r=0.90, P<0.01; Y value: r=0.91, P<0.01), however, no significant difference were found between the two instruments.The widest 95% LoA was-0.11-0.14 mm for X coordinate and-0.10-0.11 mm for Y.CONCLUSION: Pentacam and Keratron Scout showed excellent repeatability and agreement in Kappa angle assessment.The two instruments could aid and verify each other.
引文
1 Yeo JH,Moon NJ,Lee JK.Measurement of Angle Kappa Using Ultrasound Biomicroscopy and Corneal Topography.Korean J Ophthalmol 2017;31(3):257-262
2 Roberts C.Characterization of the inherent error in a spherically-biased corneal topography system in mapping a radially aspheric surface.J Refract Corneal Surg 1994;10(2):103-116
3 Kataria P,Padmanabhan P,Gopalakrishnan A,et al.Accuracy of Scheimpflug-derived corneal biomechanical and tomographic indices for detecting subclinical and mild keratectasia in a South Asian population.J Cataract Refract Surg 2019;45(3):328-336
4 Moshirfar M,Hoggan RN,Muthappan V.Angle Kappa and its importance in refractive surgery.Oman J Ophthalmol 2013;6(3):151-158
5 de Ortueta D,Arba-Mosquera S.Laser in situ keratomileusis for high hyperopia with corneal vertex centration and asymmetric offset.Eur J Ophthalmol 2016;27(2):141-152
6 Park CY,Oh SY,Chuck RS.Measurement of angle kappa and centration in refractive surgery.Curr Opin Ophthalmol 2012;23(4):269-275
7 Khakshoor H,McCaughey MV,Vejdani AH,et al.Use of angle kappa in myopic photorefractive keratectomy.Clin Ophthalmol 2015;9:193-195
8 Liu ML,Sun Y,Wang DY,et al.Decentration of Optical Zone Center and Its Impact on Visual Outcomes Following SMILE.Cornea 2015;34(4):392-397
9 Karhanova M,Pluhacek F,Mlcak P,et al.The importance of angle kappa evaluation for implantation of diffractive multifocal intra-ocular lenses using pseudophakic eye model.Acta Ophthalmol 2015;93(2):e123-128
10 Alió JL,Pikkel J.Multifocal Intraocular Lenses:The Art and the Practice.Essentials Ophthalmol 2014:29-37
11 Domínguez-Vicent A,Monsálvez-Romín D,Pérez-Vives C,et al.Measurement of angle Kappa with Orbscan II and Galilei G4:effect of accommodation.Graefes Arch Clin Exp Ophthalmol 2014;252(2):249-255
2 Roberts C.Characterization of the inherent error in a spherically-biased corneal topography system in mapping a radially aspheric surface.J Refract Corneal Surg 1994;10(2):103-116
3 Kataria P,Padmanabhan P,Gopalakrishnan A,et al.Accuracy of Scheimpflug-derived corneal biomechanical and tomographic indices for detecting subclinical and mild keratectasia in a South Asian population.J Cataract Refract Surg 2019;45(3):328-336
4 Moshirfar M,Hoggan RN,Muthappan V.Angle Kappa and its importance in refractive surgery.Oman J Ophthalmol 2013;6(3):151-158
5 de Ortueta D,Arba-Mosquera S.Laser in situ keratomileusis for high hyperopia with corneal vertex centration and asymmetric offset.Eur J Ophthalmol 2016;27(2):141-152
6 Park CY,Oh SY,Chuck RS.Measurement of angle kappa and centration in refractive surgery.Curr Opin Ophthalmol 2012;23(4):269-275
7 Khakshoor H,McCaughey MV,Vejdani AH,et al.Use of angle kappa in myopic photorefractive keratectomy.Clin Ophthalmol 2015;9:193-195
8 Liu ML,Sun Y,Wang DY,et al.Decentration of Optical Zone Center and Its Impact on Visual Outcomes Following SMILE.Cornea 2015;34(4):392-397
9 Karhanova M,Pluhacek F,Mlcak P,et al.The importance of angle kappa evaluation for implantation of diffractive multifocal intra-ocular lenses using pseudophakic eye model.Acta Ophthalmol 2015;93(2):e123-128
10 Alió JL,Pikkel J.Multifocal Intraocular Lenses:The Art and the Practice.Essentials Ophthalmol 2014:29-37
11 Domínguez-Vicent A,Monsálvez-Romín D,Pérez-Vives C,et al.Measurement of angle Kappa with Orbscan II and Galilei G4:effect of accommodation.Graefes Arch Clin Exp Ophthalmol 2014;252(2):249-255