清淋合剂治疗慢性前列腺炎(湿热下注型)的临床疗效研究
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摘要
目的观察清淋合剂治疗慢性前列腺炎(湿热下注型)的临床疗效。方法选取2017年3月至2017年9月重庆市中医院泌尿外科诊治的慢性前列腺炎(湿热下注型)患者72例作为研究对象。随机分为治疗组(清淋合剂组)和对照组(八正散组),两组疗程为4周,观察两组患者治疗前后美国国立卫生研究院慢性前列腺炎症状评分(NIH-CPSI)、中医症状评分及前列腺液常规的变化。结果治疗组总有效率80.6%,对照组总有效率66.7%;两组患者治疗前后的前列腺液常规无明显变化,差异无统计学意义(P>0.05),NIH-CPSI评分、中医症状评分均有明显改善,差异均具有统计学意义(均P<0.05),且治疗组明显优于对照组,差异具有统计学意义(P<0.05)。结论清淋合剂治疗慢性前列腺炎(湿热下注型)临床疗效优于传统八正散组方,能更好地改善患者临床症状。
Objective To study the clinical effect of Qinglin Decoction in thetreatment of chronic prostatitis with damp-heat accumulated in the lowerlimb. Methods A total of 72 chronic prostatitis patients with damp-heat accumulated in the lowerlimb were randomly divided into trial group(Qinglin Decoction group) and control group(Bazheng san group),both for a course of 4 weeks. The changes in NIH-CPSI score, TCM symptom score and prostate fluid routine in the two groups were observed. Results The total effective rate of trial groupandcontrol group was 80.6% and 66.7% accordingly. There was no significant change in prostate fluid routine between before and after treatment in the 2 groups(P>0.05). The NIH-CPSI score, TCM symptom scores were improved significantly after treatment with statistically significant differences(all P<0.05),and the improvement in trialgroup wasmore significant than that in the control group, with statistically significant difference( P<0.05).Conclusions The clinical curative effect of Qinglin Decoctionin the treatment of chronic prostatitis with damp-heat accumulated in the lower limbis better than that of the traditional Bazheng san, which can improve the clinical symptoms of patients.
Objective To study the clinical effect of Qinglin Decoction in thetreatment of chronic prostatitis with damp-heat accumulated in the lowerlimb. Methods A total of 72 chronic prostatitis patients with damp-heat accumulated in the lowerlimb were randomly divided into trial group(Qinglin Decoction group) and control group(Bazheng san group),both for a course of 4 weeks. The changes in NIH-CPSI score, TCM symptom score and prostate fluid routine in the two groups were observed. Results The total effective rate of trial groupandcontrol group was 80.6% and 66.7% accordingly. There was no significant change in prostate fluid routine between before and after treatment in the 2 groups(P>0.05). The NIH-CPSI score, TCM symptom scores were improved significantly after treatment with statistically significant differences(all P<0.05),and the improvement in trialgroup wasmore significant than that in the control group, with statistically significant difference( P<0.05).Conclusions The clinical curative effect of Qinglin Decoctionin the treatment of chronic prostatitis with damp-heat accumulated in the lower limbis better than that of the traditional Bazheng san, which can improve the clinical symptoms of patients.
引文
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[2] 李海松,韩亮,王彬.慢性前列腺炎的中医药研究进展与思考[J].环球中医药,2012,5(7):481-484.
[3] 中医相关专家组.慢性前列腺炎中医诊治专家共识[J].中国中西医结合杂志,2015,35(8):933-940.
[4] 常德贵,王同庆,魏永进,等.八正散加减方治疗湿热下注型慢性前列腺炎排尿症状的临床研究[J].中华男科学杂志,2010,16(7):664-668.
[5] 那彦群,叶章群,孙颖浩,等.2014版中国泌尿外科疾病诊断治疗指南[M].北京:人民卫生出版社,2014:435-454.
[6] 中国中西医结合学会男科专业委员会.慢性前列腺炎中西医结合诊疗专家共识[J].中国中西医结合杂志,2015,35(8):933-941.
[7] 贾波,李冀等.方剂学[M].上海:上海科学技术出版社,2012:211.
[8] 李广森,常德贵,张培海,等. 前泌通片对大鼠慢性非细菌性前列腺炎的治疗作用机制研究[J].中国男科学杂志,2016,30(6):15-19.
[9] 陈红风.中医外科学[M].北京.人民卫生出版社,2015:5.
[10] 周玉春,张新东,金保方,等.徐福松教授辨治慢性前列腺炎经验[J].南京中医药大学学报,2009,25(4):297-300.
[11] 李海松,韩富强,李曰庆.918例慢性前列腺炎中医证型分布研究[J].北京中医药,2008,27(6):416-418.
[12] 李广森,蔡剑,俞旭君,等.八正散加减方对慢性非细菌性前列腺炎大鼠NGF TNF-α的影响[J].四川中医,2016,34(10):40-42.
[13] 王祖龙,孙自学,李灿,等.消癥饮治疗湿热瘀阻型慢性前列腺炎200例临床观察[J].中医杂志,2008,49(8):701-703.
[14] 李广森,俞旭君,陈帝昂,等.八正散加减方对慢性非细菌性前列腺炎大鼠Th1/Th2细胞平衡影响的实验研究[J].新中医,2017,49(2):7-10.
[15] 杨静,苏宗泽,李华萍,等.八正散和五味消毒饮治疗尿路感染的临床观察[J].四川中医,2003,21(1):29-30.