复方中药制剂对女性赛艇运动员运动性月经失调影响的研究
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摘要
目的观察复方中药制剂对运动性月经失调的女性赛艇运动员生殖激素指标和能量代谢指标的调节作用。方法选用8名17～22岁天津市赛艇队患有运动性月经失调的女性赛艇运动员为研究对象,在正常训练期间,服用复方中药制剂两个月经周期。观察Gn RH(促性腺激素释放激素)、FSH(促卵泡生成素)、LH(促黄体生成素)、E2(雌二醇)、P(孕酮)、T(睾酮)、C(皮质醇)、leptin(瘦素)和TT3(三碘甲腺原氨酸)的变化。结果与服药前相比,卵泡期Gn RH、FSH显著提高(p<0.05);与服药前相比,黄体期LH、C、leptin均发生明显提高,呈非常显著性变化(p<0.01);与服药前相比,卵泡期C值下降,黄体期FSH、P值下降。结论复方中药制剂可以提高运动性月经失调的女性赛艇运动员的生殖激素水平和能量代谢水平,这对于调节机体能量分配,恢复运动员疲劳,提高身体机能有一定的效果。
Objective To observe the effects of the Chinese herbal compound preparation on exercise-induced menstrual disorders of the reproductive hormone in female rowers indicators and indexes of energy metabolism regulation. Methods 8 professional rowers aged17～22 were from the Tianjin who suffers from exercise-induced menstrual disorders of female rowers as research objects during the training period, taking Chinese herbal compound two menstrual cycles and observing their GnRH(gonadotropin releasing hormone),FSH(follicle stimulating hormone) and LH(luteinizing hormone), E2(estradiol) and P(progesterone), T(testosterone), C(cortisol), leptin(leptin) and TT3(three methyl gland original acid) changes. Results Compared with the results before, GnRH and FSH in follicular phase increased significantly(p<0.05), LH, C and leptin in luteal phase increased significantly(p<0.01), C in follicular phase decreased, FSH and P in luteal phase decreased. Conclusion Compound Chinese medicine preparation can improve the reproductive hormone level and energy metabolism level of female rowers with exercise-induced menstrual disorder, which has a certain effect on regulating body energy distribution, restoring athletes' fatigue and improving body function.
Objective To observe the effects of the Chinese herbal compound preparation on exercise-induced menstrual disorders of the reproductive hormone in female rowers indicators and indexes of energy metabolism regulation. Methods 8 professional rowers aged17～22 were from the Tianjin who suffers from exercise-induced menstrual disorders of female rowers as research objects during the training period, taking Chinese herbal compound two menstrual cycles and observing their GnRH(gonadotropin releasing hormone),FSH(follicle stimulating hormone) and LH(luteinizing hormone), E2(estradiol) and P(progesterone), T(testosterone), C(cortisol), leptin(leptin) and TT3(three methyl gland original acid) changes. Results Compared with the results before, GnRH and FSH in follicular phase increased significantly(p<0.05), LH, C and leptin in luteal phase increased significantly(p<0.01), C in follicular phase decreased, FSH and P in luteal phase decreased. Conclusion Compound Chinese medicine preparation can improve the reproductive hormone level and energy metabolism level of female rowers with exercise-induced menstrual disorder, which has a certain effect on regulating body energy distribution, restoring athletes' fatigue and improving body function.
引文
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[15]Reed J L,Souza M J D,Mallinson R J,et al.Energy availability discriminates clinical menstrual status in exercising women[J].Journal of the International Society of Sports Nutrition,2015(01):1-11.
[16]张亚刚,吾满江,艾力.药物的能量理论和中药有效组份的能量协同作用机制[J].中草药,2003,34(10):865-868.
[17]Williams N I,Reed J L,Leidy H J,et al.Estrogen and progesterone exposure is reduced in response to energy deficiency in women aged25-40 years[J].Human Reproduction,2010,25(9):2328-2339.
[18]徐月,曹建民,夏辉,等.复方中药对运动训练大鼠下丘脑神经递质的影响[C].2014年中国运动生理生化学术会议论文集,2014.
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[20]苑晓玲,王蕴红,邹延艾.运动对大鼠下丘脑GnRH和β-EP含量的影响[J].中国运动医学杂志,2000(03):270-272.
[21]O’Leary C B,Lehman C,Koltun K,et al.Response of testosterone to prolonged aerobic exercise during different phases of the menstrual cycle[J]. European Journal of Applied Physiology,2013,113(9):2419-2424.
[22]Reed J L,Souza M J D,Mallinson R J,et al.Energy availability discriminates clinical menstrual status in exercising women[J].Journal of the International Society of Sports Nutrition,2015(01):1-11.
[23]冯炜权.运动疲劳及过度训练的生化诊断—运动生物化学动态之三[J].北京体育大学学报,2000(04):498-502.
[24]王杰龙.女运动员能量负平衡与内分泌紊乱关系的实验研究[D].上海体育学院,2008.
[25]刘晓丽.补充两种糖对大鼠运动性动情周期抑制的缓解和改善[D].上海体育学院,2012.
[26]Loucks A B,Verdun M.Slow restoration of LH pulsatility by refeeding in energetically disrupted women[J]. American Journal of Physiology,1998,275(4Pt2):R1218.
[27]张缨,周帆扬,蒋建军.瘦素(Leptin)与运动[J].中国运动医学杂志,2002,21(4):405-409.
[2]付燕,熊若虹.运动性月经失调的研究进展[J].成都体育学院学报,2006(01):100-103.
[3]Warren M P.The effects of exercise on pubertal progression and reproductive function in girls[J]. Journal of Clinical Endocrinology&Metabolism,1980,51(5):1150-1157.
[4]陈千红.补糖对运动性月经失调运动员生殖激素及能量代谢的影响[D].上海体育学院,2014.
[5]王杰龙,王人卫,方子龙,等.月经失调女运动员代谢状态的研究[J].体育科学,2009,29(3):58-63.
[6]张世明,叶锐彬,虞亚明,等.运动性疲劳的中医分型和诊断标准的研究[J].中国运动医学杂志,2003(01):47-51.
[7]郑陆.体育科研中划分女子月经周期时相的常用方法及评析[J].山东体育学院学报,1996(4):25-27.
[8]Devries M,Hamadeh M S,Tarnopolsky M.Menstrual cycle phase and sex influence muscle glycogen utilization and glucose turnover during moderate-intensity endurance exercise[J]. American Journal of Physiology Regulatory Integrative&Comparative Physiology,2006,291(4):74.
[9]D'Eon T,Braun B.The roles of estrogen and progesterone in regulating carbohydrate and fat utilization at rest and during ex ercise[J].Journal of Women s Health&Gender-Based Medicine,2002,11(3):225-237.
[10]郑陆,朱琳娜,毕务萍.女子篮球运动员月经周期中运动能力变化的研究[J].体育科学,1994(06):68-72.
[11]郭海英,董晓虹,张景红.不同月经周期赛艇和短跑运动员性激素水平和运动能力的观察[J].中国运动医学杂志,2005,24(5):555-557.
[12]Devries M,Hamadeh M S,Tarnopolsky M.Menstrual cycle phase and sex influence muscle glycogen utilization and glucose turnover during moderate-intensity endurance exercise[J].American Journal of Physiology Regulatory Integrative&Comparative Physiology,2006,291(4):74.
[13]Hashimoto H,Ishijima T,Hayashida H,et al.Menstrual cycle phase and carbohydrate ingestion alter immune response following endurance exercise and high intensity time trial performance test under hot conditions[J]. Journal of the International Society of Sports Nutrition,2014,11(3):467-476.
[14]Gibbs J C,Williams N I,Mallinson R J,et al.Effect of high dietary restraint on energy availability and menstrual status[J]. Medicine&Science in Sports&Exercise,2013,45(9):1790-1797.
[15]Reed J L,Souza M J D,Mallinson R J,et al.Energy availability discriminates clinical menstrual status in exercising women[J].Journal of the International Society of Sports Nutrition,2015(01):1-11.
[16]张亚刚,吾满江,艾力.药物的能量理论和中药有效组份的能量协同作用机制[J].中草药,2003,34(10):865-868.
[17]Williams N I,Reed J L,Leidy H J,et al.Estrogen and progesterone exposure is reduced in response to energy deficiency in women aged25-40 years[J].Human Reproduction,2010,25(9):2328-2339.
[18]徐月,曹建民,夏辉,等.复方中药对运动训练大鼠下丘脑神经递质的影响[C].2014年中国运动生理生化学术会议论文集,2014.
[19]屈智超.关于中枢神经递质调节垂体促性腺激素和催乳素释放的研究进展[J].国际内分泌代谢杂志,1984(01):11-15.
[20]苑晓玲,王蕴红,邹延艾.运动对大鼠下丘脑GnRH和β-EP含量的影响[J].中国运动医学杂志,2000(03):270-272.
[21]O’Leary C B,Lehman C,Koltun K,et al.Response of testosterone to prolonged aerobic exercise during different phases of the menstrual cycle[J]. European Journal of Applied Physiology,2013,113(9):2419-2424.
[22]Reed J L,Souza M J D,Mallinson R J,et al.Energy availability discriminates clinical menstrual status in exercising women[J].Journal of the International Society of Sports Nutrition,2015(01):1-11.
[23]冯炜权.运动疲劳及过度训练的生化诊断—运动生物化学动态之三[J].北京体育大学学报,2000(04):498-502.
[24]王杰龙.女运动员能量负平衡与内分泌紊乱关系的实验研究[D].上海体育学院,2008.
[25]刘晓丽.补充两种糖对大鼠运动性动情周期抑制的缓解和改善[D].上海体育学院,2012.
[26]Loucks A B,Verdun M.Slow restoration of LH pulsatility by refeeding in energetically disrupted women[J]. American Journal of Physiology,1998,275(4Pt2):R1218.
[27]张缨,周帆扬,蒋建军.瘦素(Leptin)与运动[J].中国运动医学杂志,2002,21(4):405-409.