金纳米粒子在毛细管电泳中的应用进展
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摘要
对近年来金纳米粒子作为毛细管电色谱开管柱、整体柱和电泳微芯片固定相及缓冲溶液添加剂的应用进行了综述,并对该研究领域未来的发展方向进行展望,包括设计开发新型杂化材料、结合多种毛细管柱制备技术及深入进行相关机理研究等,为该领域今后的相关研究提供借鉴和依据。
This review summarized the recent application of gold nanoparticles in capillary electrochromatography including open-tube column,monolithic capillary and microchip as stationary phase,and buffer additives. Moreover,the future direction of the research field is prospected,including design and development of new hybrid material,integration of a variety of capillary column preparation technologies,and study on the related mechanism thoroughly etc,so as to provide reference and basis for the further investigation in this research field.
This review summarized the recent application of gold nanoparticles in capillary electrochromatography including open-tube column,monolithic capillary and microchip as stationary phase,and buffer additives. Moreover,the future direction of the research field is prospected,including design and development of new hybrid material,integration of a variety of capillary column preparation technologies,and study on the related mechanism thoroughly etc,so as to provide reference and basis for the further investigation in this research field.
引文
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[2]Hamer M,Yone A,Rezzano I.Gold nanoparticle-coated capillaries for protein and peptide analysis on open-tubular capillary electrochromatography[J].Electrophoresis,2012,33(2):334-339.
[3]陈杰,丁国生,岳春月,等.纳米粒子毛细管电泳/微流控芯片新技术及其在手性分离中的应用[J].色谱,2012,30(1):3-7.
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[7]张静姝,颜梦梦,刘春叶.毛细管电泳-内标法同时测定3种药物的解离常数[J].化学通报,2016,79(12):1166-1172.
[8]潘聪洁,王伟峰,陈兴国.毛细管电泳在手性化合物分离中的应用进展[J].色谱,2016,34(1):16-20.
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[12]叶芳贵,陆俊宇,王圆,等.金纳米粒子修饰毛细管硅胶整体柱的制备及其电色谱性能研究[J].分析化学,2011,39(3):341-345.
[13]Xu Y,Cao Q,Svec F,et al.Porous polymer monolithic column with surface-bound gold nanoparticles for the capture and separation of cysteine-containing peptides[J].Anal Chem,2010,82(8):3352-3358.
[14]Pumera M,Wang J,Grushka E,et al.Gold nanoparticleenhanced microchip capillary electrophoresis[J].Anal Chem,2001,73(22):5625-5628.
[15]Neiman B,Grushka E,Lev O.Use of gold nanoparticles to enhance capillary electrophoresis[J].Anal Chem,2001,73(21):5220-5227.
[16]Li M,Tarawally M,Liu X,et al.Application of cyclodextrin-modified gold nanoparticles in enantioselective monolith capillary electrochromatography[J].Talanta,2013,109:1-6.
[17]王雪,高超,杨栋磊,等.以金纳米溶胶为中间体同时制备阳离子及反相模式整体柱[J].分析科学学报,2015,31(1):55-58.
[18]Liu F K,Hsu Y T,Wu C H.Open tubular capillary electrochromatography using capillaries coated with films of alkanethiol-self-assembled gold nanoparticle layers[J].Journal of Chromatography A,2005,1083(1/2):205-214.
[19]O’mahony T,Owens V P,Murrihy J P,et al.Alkylthiol gold nanoparticles in open-tubular capillary electrochromatography[J].Journal of Chromatography A,2003,1004(1/2):181-193.
[20]Connolly D,Twamley B,Paull B.High-capacity gold nanoparticle functionalised polymer monoliths[J].Chem Commun,2010,46(12):2109-2111.
[21]Lu J Y,Ye F G,Zhang A Z,et al.Preparation and characterization of silica monolith modified with bovine serum albumin-gold nanoparticles conjugates and its use as chiral stationary phases for capillary electrochromatography[J].J Sep Sci,2011,34(16/17):2329-2336.
[22]Fang L L,Wang P,Wen X L,et al.Layer-by-layer self-assembly of gold nanoparticles/thiolsβ-cyclodextrin coating as the stationary phase for enhanced chiral differentiation in open tubular capillary electrochromatography[J].Talanta,2017,167:158-165.
[23]Zhao L C,Yang L M,Wang Q Q.Silica-based polypeptide-monolithic stationary phase for hydrophilic chromatography and chiral separation[J].Journal of Chromatography A,2016,1446:125-133.
[24]王娜妮,张扬,董宇,等.聚合物整体柱在中药分析中的应用[J].中华中医药学刊,2015,33(7):1716-1719.
[25]Cao Q,Xu Y,Liu F,et al.Polymer monoliths with exchangeable chemistries:use of gold nanoparticles as intermediate ligands for capillary columns with varying surface functionalities[J].Anal Chem,2010,82(17):7416-7421.
[26]刘长春,崔大付,王利.聚二甲基硅氧烷微流体芯片的制作技术[J].传感器技术,2004,23(7):77-80.
[27]刘春叶,张剑,许旭.PDMS微芯片吸附牛血清白蛋白的研究[J].化学研究与应用,2009,21(5):745-748.
[28]Wang A J,Xu J J,Chen H Y.Proteins modification of poly(dimethylsiloxane)microfluidic channels for the enhanced microchip electrophoresis[J].Journal of Chromatography A,2006,1107(1/2):257-264.
[29]Wang A J,Xu J J,Zhang Q,et al.The use of poly(dimethylsiloxane)surface modification with gold nanoparticles for the microchip electrophoresis[J].Talanta,2006,69(1):210-215.
[30]Wang W,Zhao L,Zhou F,et al.Electroosmotic flowswitchable poly(dimethylsiloxane)microfluidic channel modified with cysteine based on gold nanoparticles[J].Talanta,2007,73(3):534-539.
[31]Chen Y L,Shih C J,Ferrance J,et al.Genotyping ofα-thalassemia deletions using multiplex polymerase chain reactions and gold nanoparticle-filled capillary electrophoresis[J].Journal of Chromatography A,2009,1216(7):1206-1212.
[2]Hamer M,Yone A,Rezzano I.Gold nanoparticle-coated capillaries for protein and peptide analysis on open-tubular capillary electrochromatography[J].Electrophoresis,2012,33(2):334-339.
[3]陈杰,丁国生,岳春月,等.纳米粒子毛细管电泳/微流控芯片新技术及其在手性分离中的应用[J].色谱,2012,30(1):3-7.
[4]Yang L,Guihen E,Glennon J D.Alkylthiol gold nanoparticles in sol-gel-based opentubular capillary electrochromatography[J].J Sep Sci,2005,28(8):757-766.
[5]Yang L,Guihen E,Holmes J D,et al.Gold nanoparticlemodified etched capillaries for open-tubular capillary electrochromatography[J].Anal Chem,2005,77(6):1840-1846.
[6]Yang L,Chen C J,Liu X,et al.Use of cyclodextrin-modified gold nanoparticles for enantioseparations of drugs and amino acids based on pseudostationary phase-capillary electrochromatography[J].Electrophoresis,2010,31(10):1697-1705.
[7]张静姝,颜梦梦,刘春叶.毛细管电泳-内标法同时测定3种药物的解离常数[J].化学通报,2016,79(12):1166-1172.
[8]潘聪洁,王伟峰,陈兴国.毛细管电泳在手性化合物分离中的应用进展[J].色谱,2016,34(1):16-20.
[9]Li M,Liu X,Jiang F Y,et al.Enantioselective open-tubular capillary electrochromatography using cyclodextrinmodified gold nanoparticles as stationary phase[J].Journal of Chromatography A,2011,1218(23):3725-3729.
[10]Li H F,Zeng H L,Chen Z F,et al.Chip-based enantioselective open-tubular capillary electrochromatography using bovine serum albumin-gold nanoparticle conjugates as the stationary phase[J].Electrophoresis,2009,30(6):1022-1029.
[11]Qu Q S,Zhang X X,Shen M,et al.Open-tubular capillary electrochromatography using a capillary coated with octadecylamine-capped gold nanoparticles[J].Electrophoresis,2008,29(4):901-909.
[12]叶芳贵,陆俊宇,王圆,等.金纳米粒子修饰毛细管硅胶整体柱的制备及其电色谱性能研究[J].分析化学,2011,39(3):341-345.
[13]Xu Y,Cao Q,Svec F,et al.Porous polymer monolithic column with surface-bound gold nanoparticles for the capture and separation of cysteine-containing peptides[J].Anal Chem,2010,82(8):3352-3358.
[14]Pumera M,Wang J,Grushka E,et al.Gold nanoparticleenhanced microchip capillary electrophoresis[J].Anal Chem,2001,73(22):5625-5628.
[15]Neiman B,Grushka E,Lev O.Use of gold nanoparticles to enhance capillary electrophoresis[J].Anal Chem,2001,73(21):5220-5227.
[16]Li M,Tarawally M,Liu X,et al.Application of cyclodextrin-modified gold nanoparticles in enantioselective monolith capillary electrochromatography[J].Talanta,2013,109:1-6.
[17]王雪,高超,杨栋磊,等.以金纳米溶胶为中间体同时制备阳离子及反相模式整体柱[J].分析科学学报,2015,31(1):55-58.
[18]Liu F K,Hsu Y T,Wu C H.Open tubular capillary electrochromatography using capillaries coated with films of alkanethiol-self-assembled gold nanoparticle layers[J].Journal of Chromatography A,2005,1083(1/2):205-214.
[19]O’mahony T,Owens V P,Murrihy J P,et al.Alkylthiol gold nanoparticles in open-tubular capillary electrochromatography[J].Journal of Chromatography A,2003,1004(1/2):181-193.
[20]Connolly D,Twamley B,Paull B.High-capacity gold nanoparticle functionalised polymer monoliths[J].Chem Commun,2010,46(12):2109-2111.
[21]Lu J Y,Ye F G,Zhang A Z,et al.Preparation and characterization of silica monolith modified with bovine serum albumin-gold nanoparticles conjugates and its use as chiral stationary phases for capillary electrochromatography[J].J Sep Sci,2011,34(16/17):2329-2336.
[22]Fang L L,Wang P,Wen X L,et al.Layer-by-layer self-assembly of gold nanoparticles/thiolsβ-cyclodextrin coating as the stationary phase for enhanced chiral differentiation in open tubular capillary electrochromatography[J].Talanta,2017,167:158-165.
[23]Zhao L C,Yang L M,Wang Q Q.Silica-based polypeptide-monolithic stationary phase for hydrophilic chromatography and chiral separation[J].Journal of Chromatography A,2016,1446:125-133.
[24]王娜妮,张扬,董宇,等.聚合物整体柱在中药分析中的应用[J].中华中医药学刊,2015,33(7):1716-1719.
[25]Cao Q,Xu Y,Liu F,et al.Polymer monoliths with exchangeable chemistries:use of gold nanoparticles as intermediate ligands for capillary columns with varying surface functionalities[J].Anal Chem,2010,82(17):7416-7421.
[26]刘长春,崔大付,王利.聚二甲基硅氧烷微流体芯片的制作技术[J].传感器技术,2004,23(7):77-80.
[27]刘春叶,张剑,许旭.PDMS微芯片吸附牛血清白蛋白的研究[J].化学研究与应用,2009,21(5):745-748.
[28]Wang A J,Xu J J,Chen H Y.Proteins modification of poly(dimethylsiloxane)microfluidic channels for the enhanced microchip electrophoresis[J].Journal of Chromatography A,2006,1107(1/2):257-264.
[29]Wang A J,Xu J J,Zhang Q,et al.The use of poly(dimethylsiloxane)surface modification with gold nanoparticles for the microchip electrophoresis[J].Talanta,2006,69(1):210-215.
[30]Wang W,Zhao L,Zhou F,et al.Electroosmotic flowswitchable poly(dimethylsiloxane)microfluidic channel modified with cysteine based on gold nanoparticles[J].Talanta,2007,73(3):534-539.
[31]Chen Y L,Shih C J,Ferrance J,et al.Genotyping ofα-thalassemia deletions using multiplex polymerase chain reactions and gold nanoparticle-filled capillary electrophoresis[J].Journal of Chromatography A,2009,1216(7):1206-1212.