JKOM骨关节炎功能评估量表在中药熏蒸方治疗阳虚寒凝型膝痹病疗效评价中的应用
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摘要
目的:探讨JKOM骨关节炎功能评估量表在中药熏蒸方治疗阳虚寒凝型膝痹病(knee osteoarthritis,KOA)疗效评价中的应用。方法:选取符合纳入标准患者98例,随机分为实验组和对照组.实验组采用中药熏蒸方治疗。二组在治疗后采用汉化版日本膝骨关节炎功能评估量表(JKOM)自评和中医症候评分。结果:JKOM骨关节炎功能评估量表自我评分:两组治疗后疼痛程度,日常生活、社交活动及健康状态,疼痛及僵硬感等KOM指标均有改善(P<0.05),观察组疼痛程度,日常生活、社交活动及健康状态,疼痛及僵硬感等KOM指标明显优于对照组(P<0.05)。中医症候评分:两组患者关节疼痛、压痛、肿胀以及活动障碍等中医症候评分均较治疗前下降(P<0.05),观察组各项评分均明显优于对照组(P<0.05)。两种评价方法的结果无差异(P>0.05)。结论:汉化版JKOM采用与患者密切相关的临床指标,以患者自我评分来评价中药熏洗方治疗KOA的疗效,具有良好的信度。
Objective:To study the application value of JKOM osteoarthritis function evaluation scale in the evaluation of Chinese herbal fumigation prescription in the treatment of Yang deficiency and cold coagulating type of knee arthralgia. Method:Ninety-eight patients in accordance with the inclusion criteria were selected. They were randomly divided into the experimental group and the control group. The experimental group was treated with Chinese medicine fumigation. The two group adopted the Chinese version of the Japanese knee osteoarthritis evaluation scale(JKOM) self-evaluation and TCM symptom score.Results:JKOM self score: The degree of pain, daily life, social activities and health, pain and stiffness, and other KOM indexes in the two groups after treatment were improved(P<0.05). The degree of pain daily life, social activities and health, pain and stiffness, and other KOM indications in the observation group were significantly better than those of the control group(P<0.05). TCM syndrome score: Two groups' joint pain, pressure pain, swelling and activity disorders and other TCM syndrome scores were lower than those before treatment(P<0.05), and the scores of the observation group were significantly better than those of the control group(P<0.05). There was no difference in the results of the two evaluation methods(P>0.05). Conclusion:The Chinese version of JKOM is based on the patients themselves and the clinical indicators are closely related to the patients. It has a good reliability in evaluating the efficacy of the Chinese herbal fumigation prescription in the treatment of KOA.
Objective:To study the application value of JKOM osteoarthritis function evaluation scale in the evaluation of Chinese herbal fumigation prescription in the treatment of Yang deficiency and cold coagulating type of knee arthralgia. Method:Ninety-eight patients in accordance with the inclusion criteria were selected. They were randomly divided into the experimental group and the control group. The experimental group was treated with Chinese medicine fumigation. The two group adopted the Chinese version of the Japanese knee osteoarthritis evaluation scale(JKOM) self-evaluation and TCM symptom score.Results:JKOM self score: The degree of pain, daily life, social activities and health, pain and stiffness, and other KOM indexes in the two groups after treatment were improved(P<0.05). The degree of pain daily life, social activities and health, pain and stiffness, and other KOM indications in the observation group were significantly better than those of the control group(P<0.05). TCM syndrome score: Two groups' joint pain, pressure pain, swelling and activity disorders and other TCM syndrome scores were lower than those before treatment(P<0.05), and the scores of the observation group were significantly better than those of the control group(P<0.05). There was no difference in the results of the two evaluation methods(P>0.05). Conclusion:The Chinese version of JKOM is based on the patients themselves and the clinical indicators are closely related to the patients. It has a good reliability in evaluating the efficacy of the Chinese herbal fumigation prescription in the treatment of KOA.
引文
[1] 谭开云,卢敏.加味独活寄生合剂治疗风寒湿痹、肝肾亏虚型膝骨关节炎临床疗效观察[J].中华中医药学刊,2016,34(2):425-427.
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[7] 于建伟,李慧英,汪利合,等.中药熏洗加中药封包联合关节腔内注射玻璃酸钠治疗膝骨关节炎临床观察[J].风湿病与关节炎,2015,4(2):10-12.
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[10] 李继超,赵娟,张延杰,等.补肾祛瘀通痹方治疗膝关节骨性关节炎的研究[J].光明中医,2018,23(1):49-51.
[11] 黄伟毅,魏秋实,曾健英,等.独活寄生汤配合玻璃酸钠对膝骨关节炎患者生活质量的影响[J].广东医学,2014,35(15):2447-2450
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[13] 陈伟,吕红芝,张晓琳,等.中国中老年人群膝关节骨性关节炎患病率流行病学调查设计[J].河北医科大学学报,2015,36(4):487-489.
[14] 凌云,王延涛,欧阳国容,等.关节镜术后应用止痛四物汤治疗膝骨关节炎的疗效观察[J].中医正骨,2011,23(4):1009-1011.
[15] 向珍蛹,茅建春,徐先国,等.膝骨关节炎中医证型分布的流行病学研究[J].上海中医药杂志,2012,46(12):5-8.
[16] 姜洪洋,薛剑冰,程云峰.中药熏洗治疗膝关节骨性关节炎120例报告[J].中医正骨,2004,16(7):50-51.
[17] 廖辉雄,陈得胜,余瑞莲,等.中药熏洗配合手法按摩治疗膝关节骨性关节炎临床研究[J].长春中医药大学学报,2013,29(2):300-301.
[18] 钟炜,林小妹.中药熏洗配合膝关节功能锻炼治疗膝关节骨性关节炎临床疗效观察[J].临床合理用药,2018,11(1A) :116-118.
[19] 王影,王钢,许敬丽,等.中文版膝关节损伤及骨性关节炎转归评分的信度和效度评价[J].广东医学,2015,36(16):2572-2575.
[20] Maly MR,Krupa T.Personal experience of living with knee osteoarthritis among older adults[J].Disabil Rehabil,2007,29(18):1423-1433.
[21] 徐守宇,姚新苗,吴燕,等.汉化版日本膝关节骨关节炎功能评估量表的信度研究[J].中国康复医学杂志,2014,29(8):723-725.
[2] 向珍蛹,茅建春,徐先国,等.膝骨关节炎中医证型分布的流行病学研究[J].上海中医药杂志,2012,46(12):5-8.
[3] 侯亚平.膝骨关节炎患者滑液中炎症因子的表达及其与中医证型的相关性分析[J].湖南中医药大学学报,2014,34(4):29-31.
[4] 中华医学会骨科分会.骨关节炎诊治指南(2007年版)[J].中华骨科杂志,2007,27(10):793-796.
[5] 郑筱萸.中药新药临床研究指导原则[S].北京:中国医药科技出版社,2002:349-353.
[6] 张磊,扶世杰,汪国友,等.中医外治法治疗膝关节骨性关节炎的中药用药规律研究[J].四川中医,2014,32(3):85-87.
[7] 于建伟,李慧英,汪利合,等.中药熏洗加中药封包联合关节腔内注射玻璃酸钠治疗膝骨关节炎临床观察[J].风湿病与关节炎,2015,4(2):10-12.
[8] 朱振安.重视膝关节骨关节炎的早期防治[J].中国骨伤,2010,23(12):887-889.
[9] 马玲,贾子善,肖红雨,等.膝骨性关节炎关节腔内药物注射治疗疗效评价[J].中国全科医学,2016,19(9):1067-1070.
[10] 李继超,赵娟,张延杰,等.补肾祛瘀通痹方治疗膝关节骨性关节炎的研究[J].光明中医,2018,23(1):49-51.
[11] 黄伟毅,魏秋实,曾健英,等.独活寄生汤配合玻璃酸钠对膝骨关节炎患者生活质量的影响[J].广东医学,2014,35(15):2447-2450
[12] 沈兰娟.硫酸氨基葡萄糖治疗膝关节骨性关节炎130 例的疗效及护理[J].中国药业,2013,22(7):63-64.
[13] 陈伟,吕红芝,张晓琳,等.中国中老年人群膝关节骨性关节炎患病率流行病学调查设计[J].河北医科大学学报,2015,36(4):487-489.
[14] 凌云,王延涛,欧阳国容,等.关节镜术后应用止痛四物汤治疗膝骨关节炎的疗效观察[J].中医正骨,2011,23(4):1009-1011.
[15] 向珍蛹,茅建春,徐先国,等.膝骨关节炎中医证型分布的流行病学研究[J].上海中医药杂志,2012,46(12):5-8.
[16] 姜洪洋,薛剑冰,程云峰.中药熏洗治疗膝关节骨性关节炎120例报告[J].中医正骨,2004,16(7):50-51.
[17] 廖辉雄,陈得胜,余瑞莲,等.中药熏洗配合手法按摩治疗膝关节骨性关节炎临床研究[J].长春中医药大学学报,2013,29(2):300-301.
[18] 钟炜,林小妹.中药熏洗配合膝关节功能锻炼治疗膝关节骨性关节炎临床疗效观察[J].临床合理用药,2018,11(1A) :116-118.
[19] 王影,王钢,许敬丽,等.中文版膝关节损伤及骨性关节炎转归评分的信度和效度评价[J].广东医学,2015,36(16):2572-2575.
[20] Maly MR,Krupa T.Personal experience of living with knee osteoarthritis among older adults[J].Disabil Rehabil,2007,29(18):1423-1433.
[21] 徐守宇,姚新苗,吴燕,等.汉化版日本膝关节骨关节炎功能评估量表的信度研究[J].中国康复医学杂志,2014,29(8):723-725.