金匮肾气汤联合齐拉西酮在治疗抗精神病药所致男性性功能障碍中的临床疗效观察
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摘要
目的:研究金匮肾气汤联合齐拉西酮治疗抗精神病药所致男性性功能障碍的临床效果。方法:纳入此次研究的90例男性性功能障碍患者均为2017年1月-2018年8月期间收治,根据随机分组的形式将其分为三组,Ⅰ组患者30例,服用欧兰宁进行治疗,Ⅱ组患者30例,服用齐拉西酮进行治疗,Ⅲ组患者30例,服用金匮肾气汤联合齐拉西酮进行治疗,对其治疗效果进行分析。结果:①Ⅰ组患者与Ⅱ组治疗总有效率比较差异无统计学意义(P> 0.05);Ⅲ组患者治疗总有效率高于Ⅰ组与Ⅱ组患者,数据差异显著(P <0.05)。②治疗前三组患者国际勃起功能评分(ILEF-5)评分比较差异均无统计学意义(P> 0.05);治疗后Ⅰ组与Ⅱ组患者ILEF-5评分差异无统计学意义(P> 0.05);治疗后Ⅲ组患者ILEF-5均优于Ⅰ组与Ⅱ组患者,数据差异显著,有统计学意义(P <0.05)。结论:金匮肾气汤联合齐拉西酮治疗抗精神药所致男性性功能障碍的效果较为理想,值得在临床广泛推广使用。
Objective: To investigate clinical efficacy of the Jingui Shenqi decoction( 金匮肾气汤) plus ziprasidone on male sexual dysfunction from antipsychotics. Methods: 90 cases were divided into 3 groups, 30 cases in each. The group I was given Oulanning( 欧兰宁); the group II was given ziprasidone; and the group III was given the Jingui Shenqi decoction plus ziprasidone. Results: There was no significant difference of the total efficacy between group I and group II(P>0.05). The total efficacy in group III was highest(P<0.05). There was no significant difference in ILEF-5 scores among three groups before treatment(P>0.05). After treatment, there was no significant difference in ILEF-5 score between group I and group II(P>0.05). ILEF-5 in group III was better than group I and II(P<0.05). Conclusion:The Jingui Shenqi decoction plus ziprasidone on male sexual dysfunction caused by antipsychotics show a good effect, and is worthy of promotion.
Objective: To investigate clinical efficacy of the Jingui Shenqi decoction( 金匮肾气汤) plus ziprasidone on male sexual dysfunction from antipsychotics. Methods: 90 cases were divided into 3 groups, 30 cases in each. The group I was given Oulanning( 欧兰宁); the group II was given ziprasidone; and the group III was given the Jingui Shenqi decoction plus ziprasidone. Results: There was no significant difference of the total efficacy between group I and group II(P>0.05). The total efficacy in group III was highest(P<0.05). There was no significant difference in ILEF-5 scores among three groups before treatment(P>0.05). After treatment, there was no significant difference in ILEF-5 score between group I and group II(P>0.05). ILEF-5 in group III was better than group I and II(P<0.05). Conclusion:The Jingui Shenqi decoction plus ziprasidone on male sexual dysfunction caused by antipsychotics show a good effect, and is worthy of promotion.
引文
[1]邱翔.齐拉西酮急性期联合奥氮平治疗精神分裂症及长期疗效评估[J].心理医生,2017,23(17):45-46.
[2]闫耀宇,隋爱民.不同抗精神病药物对男性精神分裂症患者性功能的影响[J].浙江医学,2014,36(14):1252-1254.
[3]郭艳蕊,张晨光,郭世龙,等.阿立哌唑与利培酮对儿童少年期精神分裂症患者血清催乳素水平的影响[J].郑州大学学报(医学版),2013,48(02):279-280.
[4]张懿,刘浔雄,虞贝贝,等.抗精神病药物利培酮对男性首发精神分裂症患者性功能的影响及干预研究[J].医学信息,2014,11(02):416-417.
[5]梁海霞,刘珊珊,李芳等.利培酮合并氨磺必利致性功能障碍1例[J].中国医院用药评价与分析,2016,16(02):283-284.
[6]谢秀东,刘永华,刘典英,等.抗精神病药对恢复期男精神分裂症患者性功能及性心理的影响[J].江西医药,2018,53(02):107-109.
[7]杨栋.抗精神病药物引起高泌乳素血症的相关研究及临床管理策略[J].现代医药卫生,2018,34(10):1505-1508.
[8]朱亮.常用抗精神病药物治疗慢性精神分裂症疗效分析[J].中国卫生产业,2014,23(27):104-105.
[9]抗精神病药相关性高泌乳素血症可影响性功能[J].中国医学创新,2017,14(22):封3.
[10]杨金玲,刘兰英.中医药对于抗精神病药物引起的催乳素增高的治疗新进展[A].//第十三届全国中西医结合精神疾病学术会议论文集[C].2014:243-246.
[2]闫耀宇,隋爱民.不同抗精神病药物对男性精神分裂症患者性功能的影响[J].浙江医学,2014,36(14):1252-1254.
[3]郭艳蕊,张晨光,郭世龙,等.阿立哌唑与利培酮对儿童少年期精神分裂症患者血清催乳素水平的影响[J].郑州大学学报(医学版),2013,48(02):279-280.
[4]张懿,刘浔雄,虞贝贝,等.抗精神病药物利培酮对男性首发精神分裂症患者性功能的影响及干预研究[J].医学信息,2014,11(02):416-417.
[5]梁海霞,刘珊珊,李芳等.利培酮合并氨磺必利致性功能障碍1例[J].中国医院用药评价与分析,2016,16(02):283-284.
[6]谢秀东,刘永华,刘典英,等.抗精神病药对恢复期男精神分裂症患者性功能及性心理的影响[J].江西医药,2018,53(02):107-109.
[7]杨栋.抗精神病药物引起高泌乳素血症的相关研究及临床管理策略[J].现代医药卫生,2018,34(10):1505-1508.
[8]朱亮.常用抗精神病药物治疗慢性精神分裂症疗效分析[J].中国卫生产业,2014,23(27):104-105.
[9]抗精神病药相关性高泌乳素血症可影响性功能[J].中国医学创新,2017,14(22):封3.
[10]杨金玲,刘兰英.中医药对于抗精神病药物引起的催乳素增高的治疗新进展[A].//第十三届全国中西医结合精神疾病学术会议论文集[C].2014:243-246.