摘要
目的:探讨冠心病患者的血清降钙素原、中性粒细胞淋巴细胞计数比值等相关临床指标与肺部感染发生之间的关系,为冠心病患者合并肺部感染的临床诊治提供依据。方法:选取冠心病患者128例,根据患者是否发生肺部感染,分成了感染组和对照组各64例,检测并比较两组患者血清降钙素原(PCT)、血清前白蛋白(PA)、白细胞计数(WBC)、淋巴细胞计数(LyC)、中性粒细胞计数(NeuC)和中性粒细胞淋巴细胞计数比值(NLR)。结果:感染组PCT浓度(3.67±1.62)ng/ml,显著高于对照组(0.03±0.01)ng/ml,感染组PA浓度(164.34±45.45)mg/L,显著低于对照组(228.34±65.93)mg/L,感染组WBC、NeuC、LyC、CRP和NLR分别为(8.88±3.21)×109/L、(6.83±1.24)×109/L、(3.46±0.45)×109/L、(47.65±6.54)mg/L和(4.99±1.24),分别显著高于对照组(5.16±1.03)×109/L、(3.12±0.34)×109/L、(1.44±0.21)×109/L、(3.45±1.11)mg/L和(1.89±0.65)。结论:血清降钙素原、中性粒细胞淋巴细胞计数比值等相关临床指标的监测,对于冠心病患者肺部感染的诊断和鉴别具有重要的临床意义。
Objective:To investigate the relationship of serum procalcitonin,neutrophil lymphocyte counts and other clinical parameters in patients with coronary heart disease and pulmonary infection,so as to provide the basis for the clinical diagnosis and treatment in patients with coronary heart disease with pulmonary infection.Methods:128 cases of coronary heart disease in our hospital were chosen.According to whether pulmonary infection,they were divided into the infection group and the control group,and 64 cases in each group.The serum procalcitonin(PCT),prealbumin(PA),white blood cell count(WBC),lymphocyte count(LyC),neutrophil count(NeuC)and neutrophil lymphocyte count ratio(NLR)between the two groups were compared.Results:The PCT concentration of the infection patients was(3.67±1.62)ng/ml,significantly higher than the control group of(0.03±0.01)ng/ml,PA concentration in the infection patients was(164.34±45.45)mg/L,significantly lower than the control group of(228.34±65.93)mg/L,the WBC,NeuC,LyC,CRP and NLR in the infection group were respectively(8.88 ± 3.21)× 109/L,(6.83±1.24)× 109/L,(3.46±0.45)×109/L,(47.65±6.54)mg/L and(4.99±1.24),significantly higher than the control group of(5.16±1.03)×109/L,(3.12±0.34)×109/L,(1.44±0.21)×109/L,(3.45±1.11)mg/L and(1.89±0.65).Conclusions:The monitoring of the serum procalcitonin,neutrophil lymphocyte count and other clinical indicators ratio in patients with coronary heart disease has important clinical significance for the diagnosis of patients with coronary heart disease with lung infections.
引文
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