深圳市1起家庭误食曼陀罗中毒事件调查
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摘要
目的调查分析1起家庭误食曼陀罗所致中毒事件发生的特点和原因,为曼陀罗食物中毒事件防控总结经验和提供防控参考。方法现场访谈方法收集患者发病前就餐信息、发病和临床信息;现场卫生学调查查找致病可疑食物原料,采集患者呕吐物和可疑食物原料和剩余食物进行检测分析,确定致病因素。结果此次中毒事件共发病3例,病例来自同一家庭,家庭罹患率为100%。发病中位数潜伏期30 min,3例患者均出现皮肤潮红、心动过速、视物模糊、神智异常和烦躁不安然后昏迷等表现,煲汤的原材料含有曼陀罗干花,且在患者呕吐物和剩余汤料里均检出莨菪碱、东莨菪碱成分,该原材料来自患者所住附近某药店,药店将患者求购的龙脷叶误抓成曼陀罗干花。结论该事件是由于某药店误将曼陀罗干花当作龙脷叶卖给患者,导致一家3人莨菪碱中毒事件。中毒人群限于患者1家,中毒餐次为11月8日中餐,中毒食品为曼陀罗干花猪肺汤。
Objective To investigate and analyze the causes and characteristics of a food poisoning event in a family caused by Datura stramonium, summarize experience and provide reference for the control of food poisoning caused by Datura stramonium. Methods Information about the patients' dinner, onset and clinical information were collected by means of field investigation and interview. Suspected food ingredients were identified by field hygienic investigation Patients' vomitus, suspected ingredients and leftover food were collected and analyzed to identify pathogenic factors for food poisoning. Results The three patients involved were from the same family, and the attack rate reached 100%. The median latency was 30 minutes. The three patients all developed the same symptoms including erubescence, tachycardia, blurred vision, abnormal consciousness, agitation, coma etc. Datura stramonium was found in ingredients used for making soup in field investigation;besides, hyoscyamine and scopolamine were detected from vomitus and leftover soup. Ingredients responsible this accident were derived from a drugstore near the family residence and had been mistaken as Sauropi folium requested by the patients. Conclusion The findings of investigation showed that the accident was caused by the mistake of the drugstore that took Datura stramonium as Sauropi folium and sold to the patient. The poisoned people were limited in only one family taking Datura stramonium pork lung soup in lunch on November 8.
Objective To investigate and analyze the causes and characteristics of a food poisoning event in a family caused by Datura stramonium, summarize experience and provide reference for the control of food poisoning caused by Datura stramonium. Methods Information about the patients' dinner, onset and clinical information were collected by means of field investigation and interview. Suspected food ingredients were identified by field hygienic investigation Patients' vomitus, suspected ingredients and leftover food were collected and analyzed to identify pathogenic factors for food poisoning. Results The three patients involved were from the same family, and the attack rate reached 100%. The median latency was 30 minutes. The three patients all developed the same symptoms including erubescence, tachycardia, blurred vision, abnormal consciousness, agitation, coma etc. Datura stramonium was found in ingredients used for making soup in field investigation;besides, hyoscyamine and scopolamine were detected from vomitus and leftover soup. Ingredients responsible this accident were derived from a drugstore near the family residence and had been mistaken as Sauropi folium requested by the patients. Conclusion The findings of investigation showed that the accident was caused by the mistake of the drugstore that took Datura stramonium as Sauropi folium and sold to the patient. The poisoned people were limited in only one family taking Datura stramonium pork lung soup in lunch on November 8.
引文
[1]黄蓉,梁丽静,马亚琴.曼陀罗及其变种紫花曼陀罗的形态性状比较研究[J].绿色科技,2012,11(2):8-9.
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[3]邓朝辉,罗充,刘彬,等.曼陀罗药用价值的开发和利用[J].现代生物医学进展,2011,11(7):1394-1398.
[4]王处,马青梅,陈宗然.急性曼陀罗中毒抢救与护理[J].中国实用神经疾病杂志,2012,15(8):89-91.
[5]菅向东,杨晓光,周启栋.中毒急危症诊断治疗学[M].北京:人民卫生出版社,2009:776-776.
[6]马金龙,张峰,刘萍.一起由误食曼陀罗引起的食物中毒的调查分析王处[J].现代预防医学,2015,42(3):429-430.
[7]陈大灵,袁建明,陆春花.一起群体性曼陀罗中毒的流行病学调查与反思[J].江苏预防医学,2015,26(1):53-54.
[8]孙爱霞.一起因误食曼陀罗引起中毒报告[J].河南预防医学,2013,24(4):342-342.
[2]王钊,王克安.中国疾病预防与控制指南(传染性疾病与急性中毒预防控制手册)[M].北京:华夏出版社,2000:563-564.
[3]邓朝辉,罗充,刘彬,等.曼陀罗药用价值的开发和利用[J].现代生物医学进展,2011,11(7):1394-1398.
[4]王处,马青梅,陈宗然.急性曼陀罗中毒抢救与护理[J].中国实用神经疾病杂志,2012,15(8):89-91.
[5]菅向东,杨晓光,周启栋.中毒急危症诊断治疗学[M].北京:人民卫生出版社,2009:776-776.
[6]马金龙,张峰,刘萍.一起由误食曼陀罗引起的食物中毒的调查分析王处[J].现代预防医学,2015,42(3):429-430.
[7]陈大灵,袁建明,陆春花.一起群体性曼陀罗中毒的流行病学调查与反思[J].江苏预防医学,2015,26(1):53-54.
[8]孙爱霞.一起因误食曼陀罗引起中毒报告[J].河南预防医学,2013,24(4):342-342.