BiPAP无创通气联合清肺饮治疗慢性阻塞性肺疾病急性呼吸衰竭疗效观察
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摘要
目的探索针对伴急性呼吸衰竭的慢性阻塞性肺疾病患者采用BiPAP无创通气与清肺饮联合治疗的临床效果。方法收集本科室2015年1月-2016年12月间接收的伴急性呼吸衰竭的60例慢性阻塞性肺疾病患者,随机分成2组:参考组共有30例,在接受常规治疗的同时,给予BiPAP无创通气治疗;治疗组共有30例,在参考组的治疗基础上加用清肺饮联合治疗。详细观察治疗前、治疗后两组患者的血气分析指标、心率、呼吸频率等变化。结果治疗组治疗后的pH值、PaO_2等指标较治疗前与参考组显著更高,PaCO_2指标显著更低(P<0.05);治疗组患者治疗后的心率与呼吸频率均较治疗前与参考组患者显著更低(P<0.05)。结论针对伴急性呼吸衰竭的慢性阻塞性肺疾病患者采用BiPAP无创通气与清肺饮联合治疗疗效显著,值得临床借鉴。
Objective To explore the clinical effect: with acute respiratory failure in patients with chronic obstructive pulmonary disease with BiPAP noninvasive ventilation with Qingfeiyin combined treatment. Methods There were 30 cases in the treatment group, based on the reference on the use of Qingfei Decoction Combined treatment. The changes of blood gas analysis index, heart rate and respiratory rate were observed before and after treatment in two groups. Results After treatment, the pH value and PaO_2 index before treatment and reference group was significantly higher, PaCO_2 index was significantly lower(P<0.05); heart rate and respiratory rate in treatment group after treatment than before treatment and control group were significantly lower(P<0.05). Conclusion For with acute respiratory failure in patients with chronic obstructive pulmonary disease with BiPAP noninvasive ventilation with Qingfeiyin combined treatment effect is significant, worthy of clinical reference.
Objective To explore the clinical effect: with acute respiratory failure in patients with chronic obstructive pulmonary disease with BiPAP noninvasive ventilation with Qingfeiyin combined treatment. Methods There were 30 cases in the treatment group, based on the reference on the use of Qingfei Decoction Combined treatment. The changes of blood gas analysis index, heart rate and respiratory rate were observed before and after treatment in two groups. Results After treatment, the pH value and PaO_2 index before treatment and reference group was significantly higher, PaCO_2 index was significantly lower(P<0.05); heart rate and respiratory rate in treatment group after treatment than before treatment and control group were significantly lower(P<0.05). Conclusion For with acute respiratory failure in patients with chronic obstructive pulmonary disease with BiPAP noninvasive ventilation with Qingfeiyin combined treatment effect is significant, worthy of clinical reference.
引文
[1]刘莉丽,孟建斌,王文欣,等.纳洛酮联合无创正压通气治疗慢性阻塞性肺疾病合并呼吸衰竭的临床研究[J].中国临床药理学杂志,2016,32(16):1443-1445.
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[7]蔡明文.无创呼吸机联合纳洛酮治疗老年COPD并发呼吸衰竭的临床疗效分析[J].临床肺科杂志,2013,18(3):474-475.
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[9]赖树初,陈恩超,许旭东,等.BiPAP无创通气联合痰热清注射液治疗慢性阻塞性肺疾病急性呼吸衰竭疗效观察[J].中国现代药物应用,2013,7(13):32-34.
[10]朱齐琦,李军,尹庆纯,等.双水平气道正压(BiPAP)无创通气治疗慢性阻塞性肺疾病(COPD)并发Ⅱ型呼吸衰竭临床疗效分析[J].国际医药卫生导报,2012,18(20):3014-3016.
[11]柯彤.中西医结合治疗慢性阻塞性肺疾病急性加重合并呼吸衰竭的效果[J].中国医药导报,2015,12(6):103-106.
[12]曾湘,黄磊,伍世葵,等.温肾清肺饮治疗慢性阻塞性肺疾病急性加重期30例临床观察[J].中医药导报,2013,19(5):39-40.
[2]沈贵洪,张治,许灿龙,等.纳洛酮与无创呼吸机联合治疗老年慢性阻塞性肺疾病并发呼吸衰竭的疗效[J].中国老年学杂志,2014,34(7):1827-1828.
[3]中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南(2013年修订版)[J].中华结核和呼吸杂志,2013,36(4):255-264.
[4]陈云辉,郑利先,罗巍,等.老年慢性阻塞性肺疾病合并呼吸衰竭应用无创机械通气的治疗效果[J].中国老年学杂志,2013,33(18):4555-4556.
[5]马云涛,李涛.纳洛酮联合无创正压通气对慢性阻塞性肺疾病并发呼吸衰竭患者的临床疗效分析[J].中国处方药,2017,15(1):80-81.
[6]刘鸿翔,南勇,石斌,等.慢性阻塞性肺疾病急性加重期合并呼吸衰竭患者的痰病原菌学分析[J].实用医学杂志,2013,29(8):1347-1349.
[7]蔡明文.无创呼吸机联合纳洛酮治疗老年COPD并发呼吸衰竭的临床疗效分析[J].临床肺科杂志,2013,18(3):474-475.
[8]董晓娜.无创呼吸机治疗慢性阻塞性肺疾病合并呼吸衰竭的临床疗效探讨[J].中国医学前沿杂志(电子版),2016,8(5):87-90.
[9]赖树初,陈恩超,许旭东,等.BiPAP无创通气联合痰热清注射液治疗慢性阻塞性肺疾病急性呼吸衰竭疗效观察[J].中国现代药物应用,2013,7(13):32-34.
[10]朱齐琦,李军,尹庆纯,等.双水平气道正压(BiPAP)无创通气治疗慢性阻塞性肺疾病(COPD)并发Ⅱ型呼吸衰竭临床疗效分析[J].国际医药卫生导报,2012,18(20):3014-3016.
[11]柯彤.中西医结合治疗慢性阻塞性肺疾病急性加重合并呼吸衰竭的效果[J].中国医药导报,2015,12(6):103-106.
[12]曾湘,黄磊,伍世葵,等.温肾清肺饮治疗慢性阻塞性肺疾病急性加重期30例临床观察[J].中医药导报,2013,19(5):39-40.