神经妥乐平联合神经节苷脂对腰椎间盘突出症术后神经功能的影响
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摘要
目的观察神经妥乐平联合神经节苷脂对腰椎间盘突出症术后神经功能的影响。方法选取医院急诊科收治的腰椎间盘突出症术后残留神经症状的患者166例为研究对象,随机分为观察组和对照组,每组83例。对照组予以神经妥乐平静脉注射,观察组在对照组基础上予以神经节苷脂静脉注射。比较2组治疗前、后视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)评分及疗效。结果 2组VAS、ODI评分较治疗前均下降,且观察组治疗后VAS、ODI评分低于对照组(P <0. 01);观察组治疗优良率为80. 72%,高于对照组的62. 65%(P <0. 01)。结论对腰椎间盘突出术后残留神经症状患者予以神经妥乐平联合神经节苷脂静脉注射,能减轻患者疼痛和促进神经功能恢复。
Objective To observe the effect of neurotropin combined with ganglioside on the neurological function after lumbar disc herniation surgery. Methods 166 patients with residual neurological symptoms after operation of lumbar disc herniation were randomly divided into observation group and control group,83 cases in each group. The control group was treated with neurotropin,while the observation group was treated with ganglioside on the basis of the control group. The sensory analogue scale( VAS) and Oswestry dysfunction index( ODI) were compared before and after treatment. Results The scores of VAS and ODI in the two groups were lower than those before treatment,and the scores of VAS and ODI in the observation group were lower than those in the control group after treatment( P < 0. 01). The excellent and good rate of the observation group was 80. 72%,which was higher than 62. 65% of the control group( P < 0. 01). Conclusion Neurotropin combined with ganglioside can relieve pain and promote the recovery of nerve function in patients with residual neurological symptoms after lumbar disc herniation.
Objective To observe the effect of neurotropin combined with ganglioside on the neurological function after lumbar disc herniation surgery. Methods 166 patients with residual neurological symptoms after operation of lumbar disc herniation were randomly divided into observation group and control group,83 cases in each group. The control group was treated with neurotropin,while the observation group was treated with ganglioside on the basis of the control group. The sensory analogue scale( VAS) and Oswestry dysfunction index( ODI) were compared before and after treatment. Results The scores of VAS and ODI in the two groups were lower than those before treatment,and the scores of VAS and ODI in the observation group were lower than those in the control group after treatment( P < 0. 01). The excellent and good rate of the observation group was 80. 72%,which was higher than 62. 65% of the control group( P < 0. 01). Conclusion Neurotropin combined with ganglioside can relieve pain and promote the recovery of nerve function in patients with residual neurological symptoms after lumbar disc herniation.
引文
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[2]张俊,余化龙,刘亚东,等.脊柱内镜下不同手术入路方法治疗腰椎间盘突出症的效果[J].中国医药导报,2017,14(9):90-102.
[3]杨芳,林蓉.鼠神经生长因子与神经节苷脂治疗腰椎间盘突出症术后神经功能恢复的比较研究[J].中国骨与关节杂志,2018,7(6):468-470. DOI:10. 3969/j. issn. 2095-252X. 2018. 06. 014.
[4]蒋协远,王大伟.骨科临床疗效评价标准[M].北京:人民卫生出版社,2005:9-11.
[5]周谋望,岳寿伟,何成奇,等.“腰椎间盘突出症的康复治疗”中国专家共识[J].中国康复医学杂志,2017,32(2):129-135. DOI:10. 3969/j. issn. 1001-1242. 2017. 02. 001.
[6]高春鹏,姜宏,余鹏飞,等.中医药保守疗法促进腰椎间盘突出重吸收作用机制的研究进展[J].辽宁中医杂志,2016,43(6):1331-1334.
[7]刘春枝,梅伟,陈宾,等.神经妥乐平片治疗腰椎间盘突出症下肢神经症状的临床疗效观察[J].中国煤炭工业医学杂志,2015,18(4):560-562.
[8]陈文坚,林阳.神经妥乐平片治疗腰椎间盘突出症下肢神经症状的临床疗效观察[J].贵州医科大学学报,2017,10(10):1187-1190.
[9]林红,周健,车武,等.神经妥乐平联合甲钴胺治疗退变性腰椎疾病术后残余下肢神经症状的临床研究[J].复旦学报(医学版),2018,45(1):40-44. DOI:10. 3969/j. issn. 1672-8467. 2018. 01.006.
[10]孙宝枢.神经节苷脂对重型颅脑损伤患者术后神经功能的影响[J].中国实用神经疾病杂志,2013,16(19):87-88.