硒蛋白粉对小鼠生长、血液生化指标和全血硒含量的影响
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摘要
为了研究硒蛋白粉对小鼠生长性能、血液生化指标和全血硒含量的影响,试验选择体重在23 g左右的健康清洁级昆明小鼠20只(雌、雄各半),随机分为对照组和硒蛋白粉组。对照组饲喂普通全价日粮,其中添加亚硒酸钠(每克日粮中含硒0.1μg),硒蛋白粉组饲喂相同普通全价日粮,以硒蛋白粉替代亚硒酸钠添加于日粮中(每克日粮中含硒0.1μg),试验期为21 d。结果表明:硒蛋白粉组小鼠生长性能、脏器指数、血液生化各项指标与对照组相比差异均不显著(P>0.05);硒蛋白粉组小鼠的全血硒含量与对照组相比显著提高(P<0.05)。说明硒蛋白粉对小鼠的生长性能、脏器指数、血液生化指标均无显著影响(P>0.05),而能显著增加全血硒含量(P<0.05)。
The current study was conducted to investigate the effects of selenium protein powder on growth performance,the biochemistry indexes and selenium content were test in blood in mice. Twenty healthy SD mice,average body weight 23 g,were randomly divided into two groups,control group and selenium protein powder group. In control group,mice were fed by basal diet adding with sodium selenite 0. 1 μg/g. In selenium protein powder group,mice were fed with basal diet adding with selenium protein powder 0. 1 μg/g instesad of sodium selenite. The experiment was carried out for 21 days. The results showed that in selenium protein powder group,the growth performance,visceral index and blood biochemistry indices of mice has no significant difference when compared with control group( P ﹥ 0. 05),while the selenium content in blood was significant higher than that of control group( P < 0. 05). These data demonstrated that the Selenium protein powder had no adverse effects on the growth performance( P ﹥ 0. 05),viscera index and blood biochemical in mice,but could significantly increase the selenium content in whole blood( P < 0. 05).
The current study was conducted to investigate the effects of selenium protein powder on growth performance,the biochemistry indexes and selenium content were test in blood in mice. Twenty healthy SD mice,average body weight 23 g,were randomly divided into two groups,control group and selenium protein powder group. In control group,mice were fed by basal diet adding with sodium selenite 0. 1 μg/g. In selenium protein powder group,mice were fed with basal diet adding with selenium protein powder 0. 1 μg/g instesad of sodium selenite. The experiment was carried out for 21 days. The results showed that in selenium protein powder group,the growth performance,visceral index and blood biochemistry indices of mice has no significant difference when compared with control group( P ﹥ 0. 05),while the selenium content in blood was significant higher than that of control group( P < 0. 05). These data demonstrated that the Selenium protein powder had no adverse effects on the growth performance( P ﹥ 0. 05),viscera index and blood biochemical in mice,but could significantly increase the selenium content in whole blood( P < 0. 05).
引文
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[12]王伟伟,王宝维,耿欣,等.富硒鹅肥肝对大鼠高脂血症的修复研究[J].中国农业科学,2011,44(5):1029-1039.
[13]王昕,王岩,秦顺义,等.羧甲基壳聚糖硒对肉兔全血硒含量以及血清抗氧化功能的影响[J].黑龙江畜牧兽医,2015(07上):212-215.
[14]陈秀芸,滑静,王晓霞,等.饲粮添加硒化壳聚糖对蛋用种公鸡血液指标的影响[J].北京农学院学报,2013,28(2):31-34.
[2]WANG Y,WU Y,LUO K,et al.The protective effects of seleniumon cadmium-induced oxidative stress and apoptosis via mitochondria pathway in mice kidney[J].Food Chem Toxicol,2013(58):61-67.
[3]张建刚,侯玉洁,周美玲,等.硒在养猪生产中的应用研究进展[J].养猪,2013(1):13-16.
[4]武晓英,张春香,任有蛇,等.硒与动物疾病防治[J].中国畜牧兽医,2009,36(12):125-127.
[5]江素梅.有机硒在猪生产上的应用[J].饲料研究,2013(7):31-32.
[6]王昕,王岩,秦顺义,等.不同剂量硒蛋白粉对大鼠血常规指标和血液生化指标的影响[J].中国畜牧兽医,2014,41(7):148-152.
[7]张巧娥,杨库,崔慰贤,等.不同硒水平对生长育肥猪生产性能的影响[J].黑龙江畜牧兽医,2003(8):6-9.
[8]MEHDI Y,HORNICK J L,ISTASSE L,et al.Selenium in the environment,metabolism and involvement in body functions[J].Molecules,2013,18(3):3292-3311.
[9]刘连生,刘妍,宋念艺,等.锌硒对大鼠血清中BUN含量和ALT活性的影响[J].微量元素与健康研究,2007,24(2):9-10.
[10]李桂芝,王守训,郭健.硒单独使用或与Vit E协同作用对大鼠血清脂质过氧化物和ALT的影响[J].微量元素与健康研究,2001,18(1):9-10.
[11]钟鸣,高丹,胡昆,等.富硒蛹虫草对小鼠降血脂和抗氧化作用的影响[J].时珍国医国药,2009,20(12):3142-3144.
[12]王伟伟,王宝维,耿欣,等.富硒鹅肥肝对大鼠高脂血症的修复研究[J].中国农业科学,2011,44(5):1029-1039.
[13]王昕,王岩,秦顺义,等.羧甲基壳聚糖硒对肉兔全血硒含量以及血清抗氧化功能的影响[J].黑龙江畜牧兽医,2015(07上):212-215.
[14]陈秀芸,滑静,王晓霞,等.饲粮添加硒化壳聚糖对蛋用种公鸡血液指标的影响[J].北京农学院学报,2013,28(2):31-34.