3.0T高清弥散加权成像诊断脊髓型颈椎病
摘要
目的对比评估脊髓型颈椎病(CSM)患者颈椎高清弥散加权成像(DWI)及普通DWI图像质量,并研究高清DWI在CSM中的应用价值。方法对31例CSM患者进行SE自动导航(EPI)多次激发DWI扫描,扫描中采用外周波动门控减少脑脊液搏动伪影,同时采用自动匀场、压脂及EPI以此来减少各种可能伪影,提高图像质量及显示清晰度;将普通DWI以及高清DWI进行对比,并对所得的T2WI、DWI及表观弥散系数(ADC)图进行研究,评估高清DWI及ADC图在早期诊断CSM中的应用。结果 31例全部获取高清及普通DWI,并获得ADC值。CSM患者脊髓受压部位ADC值明显高于邻近正常未受压脊髓ADC值(P<0.05);其中2例表现为T2WI信号升高,同时受压部位ADC值升高;余29例表现为T2WI等信号,23例ADC值升高,DWI显示高低信号组间受压部分平均ADC值无统计学差别(P>0.05),但DWI高低信号组与无信号变化组间ADC值存在差异,无信号组与相邻正常脊髓间也存在差异(P<0.05)。高清DWI与普通DWI所得图像相比,信噪比(SNR)及图像分辨率有所提高,而变形程度有所降低。结论多次激发DWI扫描相较于单次激发DWI扫描而言,具有更高的图像质量,并且前者可以更早、更准确地判断脊髓内部变化,较常规T2WI具有更高的敏感性及特异性。
引文
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2 Zhang JS,Huan Y.Multishot duffusion-weighted MR imaging features in acute trauma of spinal cord[J].Eur Radiol,2014;24(3):685-92.
3 Bammer R,Augustin M,Prokesch RW,et al.Diffusion-weighted imaging of the spinal cord:interleaved echo-planar imaging is superior to fast spinecho[J].J Magn Reson Imaging,2002;15(4):364-73.
4 Bammer R,Fazekas F.Diffusion imaging of the human spinal cord and the vertebral column[J].Top Magn Reson Imaging,2003;14(6):461-76.
5 Porter DA,Hridemann RM.High resolution diffusion-weighted imaging using readout-segmented echo planar imaging,parallel imaging and a twodimensional navigator-based reacquisition[J].Magn Reson Med,2009;62(2):468-75.
6 Holdsworth SJ,Skare S,Newbould RD,et al.Robust GRAPPA-acclerated diffusion-weighted readout-segmented(RS)-EPI[J].Magn Reson Med,2009;62(6):1629-40.
2 Zhang JS,Huan Y.Multishot duffusion-weighted MR imaging features in acute trauma of spinal cord[J].Eur Radiol,2014;24(3):685-92.
3 Bammer R,Augustin M,Prokesch RW,et al.Diffusion-weighted imaging of the spinal cord:interleaved echo-planar imaging is superior to fast spinecho[J].J Magn Reson Imaging,2002;15(4):364-73.
4 Bammer R,Fazekas F.Diffusion imaging of the human spinal cord and the vertebral column[J].Top Magn Reson Imaging,2003;14(6):461-76.
5 Porter DA,Hridemann RM.High resolution diffusion-weighted imaging using readout-segmented echo planar imaging,parallel imaging and a twodimensional navigator-based reacquisition[J].Magn Reson Med,2009;62(2):468-75.
6 Holdsworth SJ,Skare S,Newbould RD,et al.Robust GRAPPA-acclerated diffusion-weighted readout-segmented(RS)-EPI[J].Magn Reson Med,2009;62(6):1629-40.