复发脑梗死危险因素与中医体质的相关性研究
摘要
目的:探讨复发脑梗死的危险因素与中医体质的相关性,为辨质论治脑梗死提供思路与方法。方法:回顾性纳入复发脑梗死患者156例为复发组,初发脑梗死患者156例为初发组,所有患者均进行中医体质辨识、采集人口学资料和危险因素。单因素分析和二元多因素Logistic回归分析复发脑梗死的危险因素与中医体质的相关性。结果:单因素分析显示高血压、糖尿病、高同型半胱氨酸血症、TIA、脑卒中家族史、房颤、气虚质、痰湿质、血瘀质与复发脑梗死相关。Logistic回归分析显示房颤、糖尿病、高同型半胱氨酸血症、TIA是复发脑梗死的危险因素;气虚质、痰湿质、血瘀质是复发脑梗死的危险体质。结论:糖尿病、高同型半胱氨酸血症、TIA、房颤、高同型半胱氨酸血症、气虚质、痰湿质、血瘀质是脑梗死复发的危险因素,提示可以基于体质防治脑梗死。
引文
[1] Demaerschalk B M,Kleindorfer D O,Adeoye O M,et al. Scientific Rationale for the Inclusion and Exclusion Criteria for Intravenous Alteplase in Acute Ischemic Stroke:A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association[J].Stroke,2016,47(2):581-641.
[2] Cereda C W,Petrini L,Azzola A,et al. Sleep-disordered breathing in acute ischemic stroke and transient ischemic attack:effects on short-and long-term outcome and efficacy of treatment with continuous positive airways pressure--rationale and design of the SAS CARE study[J]. International Journal of Stroke Official Journal of the International Stroke Society,2012,7(7):597-603.
[3] Shi D,Xia T,Feng H,et al. Evaluating the diagnostic value of vWF:Ag,D-D and FDP in patients with acute cerebral infarction using ROC curves[J].Experimental&Therapeutic Medicine,2014,7(6):1573.
[4]刘学红.CNP在脑卒中患者康复治疗中的应用[J].中国医药导报,2011,8(17):120-122.
[5]中华医学会神经病学分会.中国急性缺血性脑卒中诊治指南2014[J].中华神经科杂志,2015,48(4):246-257.
[6]赵冬.我国人群脑卒中发病率、死亡率的流行病学研究[J].中华流行病学杂志,2002,23(1):236-239.
[7] Yoo B R,Chan J Y,Kim M J,et al.Analysis of the Outcome and Prognostic Factors of Decompressive Craniectomy between Young and Elderly Patients for Acute Middle Cerebral Artery Infarction[J].Journal of Cerebrovascular&Endovascular Neurosurgery,2016,18(3):175-184.
[8]王国军,马涛.氟伐他汀与丁苯酞软胶囊联合治疗急性脑梗死的疗效及对血清C反应蛋白的动态影响[J].中国生化药物杂志,2014,34(7):150-152.
[9]王琦,王前奔.中医体质学说[J].科技导报,1994,12(5):38-39.
[10]王振宇,姚海强,王琦.辨体-辨病-辨证诊疗模式的临床运用[J].中医杂志,2016,57(22):1921-1924.
[11]中华中医药学会.ZYYXH/T157-2009.中医体质分类与判定[S].北京:中国中医药出版社,2009.
[12]赵建国.脑梗死[M].北京:人民卫生出版社,2012.
[13] Mohan K M,Wolfe C D,Rudd A G,et al. Risk and cumulative risk of stroke recurrence:a systematic review and meta-analysis[J].Stroke,2011,42(5):1489-1494.
[14]扈林,张燕,师允坤.缺血性脑卒中复发患者临床分析[J].青海医药杂志,2000,12(1):4-6.
[15]刘俊华,余小骊,聂建中,等.脑梗死复发的危险因素分析[J].南昌大学学报(医学版),2010,50(6):24-27.
[16]王锋,李薇薇,石学敏,等.首次脑梗死与复发性脑梗死危险因素分析[J].中华中医药杂志,2016,31(1):232-234.
[17]林耀波,谭少华.短暂性脑缺血发作进展至脑梗死相关因素分析[J].广东医学,2010,31(12):1547-1549.
[18]李芳,崔智飞,李学三,等.心房纤颤与脑梗死的关系[J].中国实用医药,2010,5(20):112-113.
[2] Cereda C W,Petrini L,Azzola A,et al. Sleep-disordered breathing in acute ischemic stroke and transient ischemic attack:effects on short-and long-term outcome and efficacy of treatment with continuous positive airways pressure--rationale and design of the SAS CARE study[J]. International Journal of Stroke Official Journal of the International Stroke Society,2012,7(7):597-603.
[3] Shi D,Xia T,Feng H,et al. Evaluating the diagnostic value of vWF:Ag,D-D and FDP in patients with acute cerebral infarction using ROC curves[J].Experimental&Therapeutic Medicine,2014,7(6):1573.
[4]刘学红.CNP在脑卒中患者康复治疗中的应用[J].中国医药导报,2011,8(17):120-122.
[5]中华医学会神经病学分会.中国急性缺血性脑卒中诊治指南2014[J].中华神经科杂志,2015,48(4):246-257.
[6]赵冬.我国人群脑卒中发病率、死亡率的流行病学研究[J].中华流行病学杂志,2002,23(1):236-239.
[7] Yoo B R,Chan J Y,Kim M J,et al.Analysis of the Outcome and Prognostic Factors of Decompressive Craniectomy between Young and Elderly Patients for Acute Middle Cerebral Artery Infarction[J].Journal of Cerebrovascular&Endovascular Neurosurgery,2016,18(3):175-184.
[8]王国军,马涛.氟伐他汀与丁苯酞软胶囊联合治疗急性脑梗死的疗效及对血清C反应蛋白的动态影响[J].中国生化药物杂志,2014,34(7):150-152.
[9]王琦,王前奔.中医体质学说[J].科技导报,1994,12(5):38-39.
[10]王振宇,姚海强,王琦.辨体-辨病-辨证诊疗模式的临床运用[J].中医杂志,2016,57(22):1921-1924.
[11]中华中医药学会.ZYYXH/T157-2009.中医体质分类与判定[S].北京:中国中医药出版社,2009.
[12]赵建国.脑梗死[M].北京:人民卫生出版社,2012.
[13] Mohan K M,Wolfe C D,Rudd A G,et al. Risk and cumulative risk of stroke recurrence:a systematic review and meta-analysis[J].Stroke,2011,42(5):1489-1494.
[14]扈林,张燕,师允坤.缺血性脑卒中复发患者临床分析[J].青海医药杂志,2000,12(1):4-6.
[15]刘俊华,余小骊,聂建中,等.脑梗死复发的危险因素分析[J].南昌大学学报(医学版),2010,50(6):24-27.
[16]王锋,李薇薇,石学敏,等.首次脑梗死与复发性脑梗死危险因素分析[J].中华中医药杂志,2016,31(1):232-234.
[17]林耀波,谭少华.短暂性脑缺血发作进展至脑梗死相关因素分析[J].广东医学,2010,31(12):1547-1549.
[18]李芳,崔智飞,李学三,等.心房纤颤与脑梗死的关系[J].中国实用医药,2010,5(20):112-113.