早期子宫内膜癌术后近期盆底肌电生理特点和远期盆底功能障碍性疾病的分析
摘要
目的探讨早期子宫内膜癌患者术后近期盆底肌电生理特点及远期盆底功能障碍性疾病的发生状况。方法选取符合条件的连续的子宫内膜癌患者72例为研究对象,前瞻性地收集研究对象的一般资料。在术后1个月应用PHENIX U2盆底康复治疗仪进行盆底肌电生理检测,术后1年评估盆底功能障碍性疾病发生状况。结果 60.6%～94.4%的患者术后盆底肌电生理指标存在异常。30例(43.5%)患者至少出现1种盆底功能障碍性疾病表现,其中以压力性尿失禁最为多见(33. 3%)。术后肌力异常者的盆底功能障碍性疾病发生率显著高于肌力正常者。结论子宫内膜癌术后早期存在明显的盆底肌电生理异常,术后远期有较高的PFD风险,术后早期进行盆底肌电生理检查有助于筛选高危患者。
引文
[1]杨丹.女性盆底功能障碍性疾病的研究进展[J].中国计划生育和妇产科,2017,9(2):11-15,19.
[2]卢一丹.老年宫颈癌子宫全切除术后患者盆底功能的超声评估[J].中华老年医学杂志,2018,37(2):188-191.
[3]曾朝阳,刘娟,周妍等.宫颈癌术后对患者盆底功能影响的研究[J].中国现代医学杂志,2018,28(3):59-63.
[4]王艳,金春香,冯丽华等.盆底功能障碍性疾病的诊治对女性生活质量的诠释[J].中国妇幼保健,2012,27(33):5412-5414.
[5]王艳.盆底功能康复治疗预防“社交癌”[J].健康博览,2015,(11):46-47.
[6] Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016[J]. CA Cancer J Clin, 2016,66(1):7-30.
[7]于岩君,尹香花.子宫内膜癌发病机制的研究进展[J].医学综述,2018,24(9):1719-1723.
[8] FlGO Committee on Gynecologic Oncology. FIGO staging for carcinoma of the vulva, cervix, and corpus uteri[J]. International Journal of Gynecology&Obstetrics, 2014, 125(2):97-98.
[9]中华医学会妇产科学分会妇科盆底学组.盆腔器官脱垂的中国诊治指南(草案)[J].中华妇产科杂志,2014,49(9):647-651.
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[11]美国结直肠外科医师协会临床实践指南委员会,丁曙晴,周惠芬,等.美国结直肠外科医师协会临床实践指南:大便失禁的治疗[J].中华消化外科杂志,2015,14(10):800-805.
[12] Luginbuehl H, Baeyens JP, Taeymans J, et al. Pelvic floor muscle activation and strength components influencing female urinary continence and stress incontinence:a systematic review[J]. Neurourol Lrodyn, 2015, 34(6):498-506.
[13]吕爱明,孙秀丽,华克勤,等.子宫颈癌患者Ⅲ型子宫切除术后盆底功能状况调查[J].中国妇产科临床杂志,2017,18(02):117-119.
[14] Potter R, Knocke TH,Fellner C, et al. Definitive radiotherapy based on HDR brachytherapy with iridium 192 in uterine cervix carcinoma:report on the Vienna Lniversity Hospital findings(1993-1997)compared to the preceding period in the context of ICRL 38recommendations[J].Cancer Radiother,2000,4(2):159-172.
[15] Nout RA, van de Poll-Franse LV, Lvbeert ML, et al. Long-term outcome and quality of life of patients with endometrial carcinoma treated with or without pelvic radiotherapy in the post operative radiation therapy in endometrial carcinoma 1(PORTEC-1)trial[J]. J Clin Oncol, 2011,29(13):1692-1700.
[16] de Boer SM, Nout RA, Jurgenliemk-Schulz 1M, et al. Long-Term Impact of Endometrial Cancer Diagnosis and Treatment on HealthRelated Quality of Life and Cancer Survivorship:Results From the Randomized PORTEC-2 Trial[J].Int J Radiat Oncol Biol Phys,2015, 93(4):797-809.
[17] Ramalingam K, Monga A. Obesity and pelvic floor dysfunction[J].Best Pract Res Clin Obstet Gynaecol,2015,29(4):541-547.
[18]张阳阳,张琨,李冬,等.子宫内膜癌发病相关危险因素的研究进展[J].中国妇幼保健,2018,33(1):219-222.
[19] Segal S, John G, Sammel M, et al. Lrinaiy incontinence and other pelvic floor disorders after radiation therapy in endometrial cancer survivors[J]. Maturitas, 2017, 105(1):83-88.
[20]中国超重肥胖医学营养治疗专家共识编写委员会.中国超重/肥胖医学营养治疗专家共识(2016年版)[J].中华糖尿病杂志,2016,8(9):525-540.
[21]谢弘扬,上官梦原,赵淑华等.女性盆底功能障碍性疾病的发病因素及盆底重建研究进展[J].中国老年学杂志,2017,37(4):1017-1019.
[22]吴梓瑛,覃亦伟,罗玉媚,等.产后早期电刺激与生物反馈治疗对盆底功能的影响价值分析[J].中国现代药物应用,2018,12(15):68-70.
[23]范良红,江锡环.盆底肌训练对宫颈癌术后盆底功能恢复的影响[J].安徽医药,2018,22(1):183-185.
[2]卢一丹.老年宫颈癌子宫全切除术后患者盆底功能的超声评估[J].中华老年医学杂志,2018,37(2):188-191.
[3]曾朝阳,刘娟,周妍等.宫颈癌术后对患者盆底功能影响的研究[J].中国现代医学杂志,2018,28(3):59-63.
[4]王艳,金春香,冯丽华等.盆底功能障碍性疾病的诊治对女性生活质量的诠释[J].中国妇幼保健,2012,27(33):5412-5414.
[5]王艳.盆底功能康复治疗预防“社交癌”[J].健康博览,2015,(11):46-47.
[6] Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016[J]. CA Cancer J Clin, 2016,66(1):7-30.
[7]于岩君,尹香花.子宫内膜癌发病机制的研究进展[J].医学综述,2018,24(9):1719-1723.
[8] FlGO Committee on Gynecologic Oncology. FIGO staging for carcinoma of the vulva, cervix, and corpus uteri[J]. International Journal of Gynecology&Obstetrics, 2014, 125(2):97-98.
[9]中华医学会妇产科学分会妇科盆底学组.盆腔器官脱垂的中国诊治指南(草案)[J].中华妇产科杂志,2014,49(9):647-651.
[10]中华医学会妇产科学分会妇科盆底学组.女性压力性尿失禁诊断和治疗指南(2017)[J].中华妇产科杂志,2017,52(5):289-293.
[11]美国结直肠外科医师协会临床实践指南委员会,丁曙晴,周惠芬,等.美国结直肠外科医师协会临床实践指南:大便失禁的治疗[J].中华消化外科杂志,2015,14(10):800-805.
[12] Luginbuehl H, Baeyens JP, Taeymans J, et al. Pelvic floor muscle activation and strength components influencing female urinary continence and stress incontinence:a systematic review[J]. Neurourol Lrodyn, 2015, 34(6):498-506.
[13]吕爱明,孙秀丽,华克勤,等.子宫颈癌患者Ⅲ型子宫切除术后盆底功能状况调查[J].中国妇产科临床杂志,2017,18(02):117-119.
[14] Potter R, Knocke TH,Fellner C, et al. Definitive radiotherapy based on HDR brachytherapy with iridium 192 in uterine cervix carcinoma:report on the Vienna Lniversity Hospital findings(1993-1997)compared to the preceding period in the context of ICRL 38recommendations[J].Cancer Radiother,2000,4(2):159-172.
[15] Nout RA, van de Poll-Franse LV, Lvbeert ML, et al. Long-term outcome and quality of life of patients with endometrial carcinoma treated with or without pelvic radiotherapy in the post operative radiation therapy in endometrial carcinoma 1(PORTEC-1)trial[J]. J Clin Oncol, 2011,29(13):1692-1700.
[16] de Boer SM, Nout RA, Jurgenliemk-Schulz 1M, et al. Long-Term Impact of Endometrial Cancer Diagnosis and Treatment on HealthRelated Quality of Life and Cancer Survivorship:Results From the Randomized PORTEC-2 Trial[J].Int J Radiat Oncol Biol Phys,2015, 93(4):797-809.
[17] Ramalingam K, Monga A. Obesity and pelvic floor dysfunction[J].Best Pract Res Clin Obstet Gynaecol,2015,29(4):541-547.
[18]张阳阳,张琨,李冬,等.子宫内膜癌发病相关危险因素的研究进展[J].中国妇幼保健,2018,33(1):219-222.
[19] Segal S, John G, Sammel M, et al. Lrinaiy incontinence and other pelvic floor disorders after radiation therapy in endometrial cancer survivors[J]. Maturitas, 2017, 105(1):83-88.
[20]中国超重肥胖医学营养治疗专家共识编写委员会.中国超重/肥胖医学营养治疗专家共识(2016年版)[J].中华糖尿病杂志,2016,8(9):525-540.
[21]谢弘扬,上官梦原,赵淑华等.女性盆底功能障碍性疾病的发病因素及盆底重建研究进展[J].中国老年学杂志,2017,37(4):1017-1019.
[22]吴梓瑛,覃亦伟,罗玉媚,等.产后早期电刺激与生物反馈治疗对盆底功能的影响价值分析[J].中国现代药物应用,2018,12(15):68-70.
[23]范良红,江锡环.盆底肌训练对宫颈癌术后盆底功能恢复的影响[J].安徽医药,2018,22(1):183-185.