酒石酸美托洛尔联合贝那普利治疗慢性充血性心力衰竭临床疗效分析
|
摘要
目的研究慢性充血性心力衰竭采用酒石酸美托洛尔联合贝那普利的治疗效果。方法研究对象取2017年1月12日至2018年5月10日我院62例慢性充血性心力衰竭患者,采取动态随机分组法,均分为2组。对照组行常规治疗,在此操作上,予以观察组酒石酸美托洛尔联合贝那普利治疗。观察2组心功能变化及不良事件发生情况。结果治疗后,观察组左室射血分数、左室收缩末期容积、左室舒张末期容积指标分别为(54.90±1.79)%、(34.82±2.61)mm、(45.71±3.42)mm,相比对照组更优,P<0.05;两组不良事件发生概率无明显差异,P>0.05。结论慢性充血性心力衰竭采用酒石酸美托洛尔联合贝那普利治疗,效果较佳,可有效改善患者心功能。
Objective To study the therapeutic effect of metoprolol tartrate combined with benazepril in chronic congestive heart failure. Methods Sixty-two patients with chronic congestive heart failure in our hospital from January 12, 2017 to May 10, 2018 were randomly divided into two groups. The control group received routine treatment. The observation group was treated with metoprolol tartrate combined with benazepril. Observe the changes of heart function and adverse events in the two groups. Results After treatment,the left ventricular ejection fraction, left ventricular end-systolic volume, and left ventricular end-diastolic volume index were(54.90±1.79)%,(34.82±2.61) mm, and(45.71±3.42) mm, respectively. The control group was better, P<0.05; there was no significant difference in the probability of adverse events between the two groups, P>0.05. Conclusion Chronic congestive heart failure treated with metoprolol tartrate combined with benazepril has better effect and can effectively improve the heart function of patients.
Objective To study the therapeutic effect of metoprolol tartrate combined with benazepril in chronic congestive heart failure. Methods Sixty-two patients with chronic congestive heart failure in our hospital from January 12, 2017 to May 10, 2018 were randomly divided into two groups. The control group received routine treatment. The observation group was treated with metoprolol tartrate combined with benazepril. Observe the changes of heart function and adverse events in the two groups. Results After treatment,the left ventricular ejection fraction, left ventricular end-systolic volume, and left ventricular end-diastolic volume index were(54.90±1.79)%,(34.82±2.61) mm, and(45.71±3.42) mm, respectively. The control group was better, P<0.05; there was no significant difference in the probability of adverse events between the two groups, P>0.05. Conclusion Chronic congestive heart failure treated with metoprolol tartrate combined with benazepril has better effect and can effectively improve the heart function of patients.
引文
[1]白芸,龙启福.美托洛尔联合贝那普利对慢性充血性心力衰竭患者心功能及NT-proBNP水平的影响[J].药物评价研究,2017, 40(11):1601-1605.
[2]孙建威.酒石酸美托洛尔治疗慢性充血性心力衰竭疗效观察[J].现代中西医结合杂志, 2013, 22(4):394-395.
[3]蔡濛,张萍.阿托伐他汀钙联合美托洛尔治疗慢性充血性心力衰竭的临床观察[J].中国药房, 2016, 27(21):2907-2909.
[4]蔡全云.贝那普利与美托洛尔联合治疗老年充血性心力衰竭疗效观察[J].新乡医学院学报, 2014, 31(3):224-225.
[5]李志强.贝那普利联合美托洛尔治疗慢性心力衰竭患者的临床疗效评价[J].实用临床医药杂志, 2013, 17(13):78-81.
[2]孙建威.酒石酸美托洛尔治疗慢性充血性心力衰竭疗效观察[J].现代中西医结合杂志, 2013, 22(4):394-395.
[3]蔡濛,张萍.阿托伐他汀钙联合美托洛尔治疗慢性充血性心力衰竭的临床观察[J].中国药房, 2016, 27(21):2907-2909.
[4]蔡全云.贝那普利与美托洛尔联合治疗老年充血性心力衰竭疗效观察[J].新乡医学院学报, 2014, 31(3):224-225.
[5]李志强.贝那普利联合美托洛尔治疗慢性心力衰竭患者的临床疗效评价[J].实用临床医药杂志, 2013, 17(13):78-81.