利用kV级CBCT识别标记物研究
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摘要
目的利用kV级CBCT和金球投影位置自动跟踪算法,计算模体中标记物最小识别角度。方法使用CBCT扫描内植标记物的模体,获得球管于0°到359.96°所拍摄图像集合;使用金球投影位置自动跟踪算法,分析计算图像集合中任意两张获得准确定位标记物三维空间坐标所需的最小角度间隔。结果通过任意两张图像确定模体内标记物三维空间坐标所需最小角度间隔为4.16°。结论该算法对CBCT扫描图像处理结果可行,不过仍需提高软硬件水平从而获得更精确结果。
Objective Using kV CBCT and golden globe projection position automatic tracking algorithm, we aimed to calculate the minimum recognition angle of the marker in the module. Methods The implanted markers were scanned by CBCT, and the image group of the ball tube from 0° to 359.96° was obtained. Then, the golden globe projection position automatic tracking algorithm was used to analyze and calculate any two images to determine the minimum angle interval of positing the 3 D coordinate accurately. Results The minimum angle interval for positing the 3 D coordinate of marker in phantom using any two images was4.16°. Conclusion This algorithm is feasible for CBCT scan image processing results, but it still needs to improve the software and hardware level to obtain more accurate results.
Objective Using kV CBCT and golden globe projection position automatic tracking algorithm, we aimed to calculate the minimum recognition angle of the marker in the module. Methods The implanted markers were scanned by CBCT, and the image group of the ball tube from 0° to 359.96° was obtained. Then, the golden globe projection position automatic tracking algorithm was used to analyze and calculate any two images to determine the minimum angle interval of positing the 3 D coordinate accurately. Results The minimum angle interval for positing the 3 D coordinate of marker in phantom using any two images was4.16°. Conclusion This algorithm is feasible for CBCT scan image processing results, but it still needs to improve the software and hardware level to obtain more accurate results.
引文
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[3]钟秋子,李高峰,修霞,等.前列腺癌根治术后IGRT疗效分析[J]中华放射肿瘤学杂志,2016,25(6):583-587.
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[6]张宗军,卢光明.双源C T及其临床应用[J].医学研究生学报,2007,4(20):416-418.
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[12]Keall PJ,Todor AD,Vedam SS,et al.On the use of EPID-based implanted marker tracking for 4D radiotherapy[J].Med Phys,2004,31(12):3492-3499.
[13]Wiersma R,Mao W,Riaz N,et al.SU-DD-A3-02:Real-time tracking of implanted fiducial markers using combined KV and MV imaging[J].Med Phys,2008,35(6Part2):2634-2634.
[14]Bernchou U,Agergaard SN,Brink C.Radiopaque marker motion during pre-treatment CBCT as a predictor of intra-fractional prostate movement[J].Acta Oncol,2013,52(6):1168-1174.
[15]Fujii T,Matsuura T,Takao S,et al.SU-F-I-11:Software development for 4D-CBCT research of real-time-image gated spot scanning proton therapy[J].Med Phys,2016,43(6):3389.
[16]Held M,Cremers F,Sneed PK,et al.Assessment of image quality and dose calculation accuracy on kV CBCT,MV CBCT,and MV CT images for urgent palliative radiotherapy treatments[J]J Appl Clin Med Phys,2016,17(2):279-290.
[2]田龙,席强,赵鑫,等.膀胱癌图像引导放疗中基于软组织灰度值与基于内植标记物的锥形束CT校准比较[J].中国医学物理学杂志,2018,35(1):31-35.
[3]钟秋子,李高峰,修霞,等.前列腺癌根治术后IGRT疗效分析[J]中华放射肿瘤学杂志,2016,25(6):583-587.
[4]容贤冰,邓烨.CBCT和EPID在体部肿瘤放疗摆位的对比研究[J]影像研究与医学应用,2017,1(11):48-49.
[5]胡逸民.肿瘤放射物理学[M].北京:原子能出版社,2003.
[6]张宗军,卢光明.双源C T及其临床应用[J].医学研究生学报,2007,4(20):416-418.
[7]田龙,席强,宋晓.膀胱CBCT图像中标记物选取的研究[J].癌症进展,2016,10(14):4738-4744.
[8]Park SJ,Ionascu D,Hacker F,et al.Automatic marker detection and 3D position reconstruction using cine EPID images for SBRT verification[J].Med Phy,2009,36(10):4536-4546.
[9]Nederveen A,Lagendijk J,Hofman P.Detection of fiducial gold markers for automatic on-line megavoltage position verification using a marker extraction kernel(MEK)[J].Int J Radiat Oncol Biol Phys,2000,47(5):1435-1442.
[10]Mao W,Wiersma RD,Xing L.Fast internal marker tracking algorithm for onboard MV and kV imaging systems[J].Med Phys,2008,35(5):1942-1949.
[11]Mao W,Riaz N,Lee L,et al.A fiducial detection algorithm for real-time image guided IMRT based on simultaneous MV and kV imaging[J].Med Phys,2008,35(8):3554-3564.
[12]Keall PJ,Todor AD,Vedam SS,et al.On the use of EPID-based implanted marker tracking for 4D radiotherapy[J].Med Phys,2004,31(12):3492-3499.
[13]Wiersma R,Mao W,Riaz N,et al.SU-DD-A3-02:Real-time tracking of implanted fiducial markers using combined KV and MV imaging[J].Med Phys,2008,35(6Part2):2634-2634.
[14]Bernchou U,Agergaard SN,Brink C.Radiopaque marker motion during pre-treatment CBCT as a predictor of intra-fractional prostate movement[J].Acta Oncol,2013,52(6):1168-1174.
[15]Fujii T,Matsuura T,Takao S,et al.SU-F-I-11:Software development for 4D-CBCT research of real-time-image gated spot scanning proton therapy[J].Med Phys,2016,43(6):3389.
[16]Held M,Cremers F,Sneed PK,et al.Assessment of image quality and dose calculation accuracy on kV CBCT,MV CBCT,and MV CT images for urgent palliative radiotherapy treatments[J]J Appl Clin Med Phys,2016,17(2):279-290.