降钙素原联合临床肺部感染评分在非发酵杆菌呼吸机相关性肺炎中的应用
摘要
<正>呼吸机相关性肺炎(VAP)是指在气管插管下行机械通气大于48 h或拔管在48 h内发生的肺部感染,为机械通气患者最容易发生的院内感染,可导致抗生素的滥用,增加细菌耐药率~([1])。降钙素原(PCT)是诊断感染性疾病具有较高灵敏度和特异度的指标,在感染性疾病的预后评估中具有重要的价值~([2])。临床肺部感染评分(CPIS)是根据患者的临床症状、
引文
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[3]李琼,张晚生,史加强,等.动态监测重症肺炎患者血清降钙素原的临床意义[J].中国实用医刊,2016,43(10):115-116.
[4]张凯,张召,成云云.降钙素原,C-反应蛋白、前清蛋白及白细胞计数在小儿重症肺炎诊断中的应用评价[J].中国实验诊断学,2016,20(7):1128-1130.
[5]Luna CM,Blanzaco D,Niederman MS,et al.Resolution of ventilator-associated pneumonia:prospective evaluation of the clinical pulmonary infection score as an early clinical predictor of outcome[J].Crit Care Med,2003,31(3):676-682.
[6]方寅飞,徐浩,冯胜春.非发酵菌在重症监护病房患者中感染分布及其耐药性研究[J].中国消毒学杂志,2015,32(5):452-454.
[7]Assicot M,Gendrel D,Carsin H,et al.High serum procaleitoninconcentrations in patients with sepsis and infection[J].Lancet,1993,341(8844):515-518.
[8]付跃峰,王兰,孔令博,等.住院患者血清降钙素原与病原微生物的关系分析[J].中国医药导报,2018,15(2):168-171.
[9]Chastre J,Wolff M,Fagon JY,et al.Comparison of 8 vs 15 days of antibiotic therapy for ventilatorassociated pneumonia in adults:a randomized trial[J].JAMA,2003,290:2588-2598.
[2]占林兵,谢波,华锋,等.血清C-反应蛋白,降钙素原及乳酸在重症肺炎中的变化及临床意义[J].中华全科医学,2015,13(3):367-368.
[3]李琼,张晚生,史加强,等.动态监测重症肺炎患者血清降钙素原的临床意义[J].中国实用医刊,2016,43(10):115-116.
[4]张凯,张召,成云云.降钙素原,C-反应蛋白、前清蛋白及白细胞计数在小儿重症肺炎诊断中的应用评价[J].中国实验诊断学,2016,20(7):1128-1130.
[5]Luna CM,Blanzaco D,Niederman MS,et al.Resolution of ventilator-associated pneumonia:prospective evaluation of the clinical pulmonary infection score as an early clinical predictor of outcome[J].Crit Care Med,2003,31(3):676-682.
[6]方寅飞,徐浩,冯胜春.非发酵菌在重症监护病房患者中感染分布及其耐药性研究[J].中国消毒学杂志,2015,32(5):452-454.
[7]Assicot M,Gendrel D,Carsin H,et al.High serum procaleitoninconcentrations in patients with sepsis and infection[J].Lancet,1993,341(8844):515-518.
[8]付跃峰,王兰,孔令博,等.住院患者血清降钙素原与病原微生物的关系分析[J].中国医药导报,2018,15(2):168-171.
[9]Chastre J,Wolff M,Fagon JY,et al.Comparison of 8 vs 15 days of antibiotic therapy for ventilatorassociated pneumonia in adults:a randomized trial[J].JAMA,2003,290:2588-2598.