木麒麟的主要成分及其药理作用研究
|
摘要
仙人掌科木麒麟属植物木麒麟在巴西传统医学中作为药用植物使用,在我国南方部分地区也有种植,并用药。木麒麟不仅含有蛋白质、纤维素以及微量元素等诸多重要营养成分,还含有甾醇、生物碱、黄酮类和萜类等生物活性成分,具有抗炎、抗癌、抑菌、抗氧化、镇痛、促进伤口愈合以及保护心血管等作用。对近年来木麒麟的安全性、营养成分、化学成分和药理作用的研究概况进行综述,为进一步开发木麒麟提供理论参考。
Pereskia aculeata Mill.(Cactus pereskia Linn.)was used as a medicinal plant in traditional Brazilian medicine.,and it was also cultivated and used as medicine in some parts of southern China. The P. aculeata contains not only important nutrients such as protein,cellulose and trace elements,but also active ingredients such as sterols,alkaloids,flavonoids and terpenoids. It also had anti-inflammatory,anti-cancer,antibacterial,antioxidant,analgesic,promoting wound healing,protecting cardiovascular and other functions. In this paper,the recent studies on the safety,nutrients,active ingredients and pharmacological effects of P. aculeata were reviewed in order to provide theoretical references for further development of P. aculeata.
Pereskia aculeata Mill.(Cactus pereskia Linn.)was used as a medicinal plant in traditional Brazilian medicine.,and it was also cultivated and used as medicine in some parts of southern China. The P. aculeata contains not only important nutrients such as protein,cellulose and trace elements,but also active ingredients such as sterols,alkaloids,flavonoids and terpenoids. It also had anti-inflammatory,anti-cancer,antibacterial,antioxidant,analgesic,promoting wound healing,protecting cardiovascular and other functions. In this paper,the recent studies on the safety,nutrients,active ingredients and pharmacological effects of P. aculeata were reviewed in order to provide theoretical references for further development of P. aculeata.
引文
[1]中国科学院中国植物志编辑委员会.木麒麟:Pereskia aculeata Mill.[M].北京:科学出版社,1999:274.
[2]Souza L F,Gasparetto B F,Lopes R R,et al.Temperature requirements for seed germination of Pereskia aculeata and Pereskia grandifolia[J].Journal of Thermal Biology,2016,57:6-10.
[3]Pinto N C,Scio E.The biological activities and chemical composition of Pereskia species(Cactaceae)-a review[J].Plant Foods Hum Nutr,2014,69(3):189-195.
[4]Kazama C C,Uchida D T,Canzi K N,et al.Involvement of arginine-vasopressin in the diuretic and hypotensive effects of Pereskia grandifolia Haw.(Cactaceae)[J].Journal of Ethnopharmacology,2012,144(1):86-93.
[5]Tan M L,Sulaiman S F,Najimuddin N,et al.Methanolic extract of Pereskia bleo(Kunth)DC.(Cactaceae)induces apoptosis in breast carcinoma,T47-D cell line[J].Journal of Ethnopharmacology,2005,96(1-2):287-294.
[6]Silva D O,Seifert M,Nora F R,et al.Acute toxicity and cytotoxicity of pereskia aculeata,a highly nutritious cactaceae Plant[J].Journal of Medicinal Food,2017,20(4):403-409.
[7]Takeiti C Y,Antonio G C,Motta E M P,et al.Nutritive evaluation of a non-conventional leafy vegetable(Pereskia aculeata Miller)[J].International Journal of Food Sciences and Nutrition,2009,60(sup1):148-160.
[8]Concei觭觔o M C,Junqueira L A,Guedes Silva K C,et al.T hermal and microstructural stability of a powdered gum derived from Pereskia aculeata Miller leaves[J].Food Hydrocolloids,2014,40:104-114.
[9]Merce A L,Landaluze J S,Mangrich A S,et al.Complexes of arabinogalactan of Pereskia aculeata and Co2+,Cu2+,Mn2+,and Ni2+[J].Bioresource technology,2001,76(1):29-37.
[10]Sobrinho S S,Costa L L,Alves C A A G,et al.Emulsified cooked sausages enriched with flour from ora-pro-nobis leaves(Pereskia aculeata Miller)[J].2015,22(1):318.
[11]Lima Junior F A,Concei觭觔o M C,Vilela De Resende J,et al.Response surface methodology for optimization of the mucilage extraction process from Pereskia aculeata Miller[J].Food Hydrocolloids,2013,33(1):38-47.
[12]Agostini-Costa T S,Pêssoa G K A,Silva D B,et al.Carotenoid composition of berries and leaves from a Cactaceae Pereskia species[J].Journal of Functional Foods,2014,11:178-184.
[13]Souza L F,De Barros I B,Mancini E,et al.Chemical composition and biological activities of the essential oils from two Pereskia species grown in Brazil[J].Nat Prod Commun,2014,9(12):1805-1808.
[14]Pinto N D C C,Duque A P D N,Pacheco N R,et al.Pereskia aculeata:A plant food with a ntinociceptive activity[J].Pharmaceutical Biology,2015,53(12):1780-1785.
[15]Pinto N D C C,Machado D C,Da Silva J M,et al.Pereskia aculeata Miller leaves present in vivo topical antiinflammatory activity in models of acute and chronic dermatitis[J].Journal of Ethnopharmacology,2015,173:330-337.
[16]Pinto N D C C,Cassini-Vieira P,Souza-Fagundes EMD,et al.Pereskia aculeata Miller leaves accelerate excisional wound healing in mice[J].Journal of Ethnopharmacology,2016,194:131-136.
[17]Pinto N D C C,Duque A P D N,Pacheco N R,et al.Pereskia aculeata:A plant food with antinociceptive activity[J].Pharmaceutical Biology,2015,53(12):1780-1785.
[18]de Souza M D S S,Barbalho S M,Guiguer E L,et al.Effects of Pereskia aculeata Miller on the Biochemical profiles and body composition of wistar rats[J].Journal of Biosciences and Medicines,2015,03(07):82-89.
[19]Barbalho S M,Guiguer L,Marinelli P S,et al.Pereskia aculeata Miller Flour:Metabolic effects and composition[J].Journal of Medicinal Food,2016,19(9):890-894.
[20]Souza L,Caputo L,Inchausti De Barros I,et al.Pereskia aculeata Muller(Cactaceae)Leaves:chemical composition and biological activities[J].International Journal of Molecular Sciences,2016,17(9):1478.
[21]Pinto Ncc SRCM.Cytotoxic and antioxidant activity of Pereskia aculeata Miller[J].Pharmacology online,2012(3):63-69.
[2]Souza L F,Gasparetto B F,Lopes R R,et al.Temperature requirements for seed germination of Pereskia aculeata and Pereskia grandifolia[J].Journal of Thermal Biology,2016,57:6-10.
[3]Pinto N C,Scio E.The biological activities and chemical composition of Pereskia species(Cactaceae)-a review[J].Plant Foods Hum Nutr,2014,69(3):189-195.
[4]Kazama C C,Uchida D T,Canzi K N,et al.Involvement of arginine-vasopressin in the diuretic and hypotensive effects of Pereskia grandifolia Haw.(Cactaceae)[J].Journal of Ethnopharmacology,2012,144(1):86-93.
[5]Tan M L,Sulaiman S F,Najimuddin N,et al.Methanolic extract of Pereskia bleo(Kunth)DC.(Cactaceae)induces apoptosis in breast carcinoma,T47-D cell line[J].Journal of Ethnopharmacology,2005,96(1-2):287-294.
[6]Silva D O,Seifert M,Nora F R,et al.Acute toxicity and cytotoxicity of pereskia aculeata,a highly nutritious cactaceae Plant[J].Journal of Medicinal Food,2017,20(4):403-409.
[7]Takeiti C Y,Antonio G C,Motta E M P,et al.Nutritive evaluation of a non-conventional leafy vegetable(Pereskia aculeata Miller)[J].International Journal of Food Sciences and Nutrition,2009,60(sup1):148-160.
[8]Concei觭觔o M C,Junqueira L A,Guedes Silva K C,et al.T hermal and microstructural stability of a powdered gum derived from Pereskia aculeata Miller leaves[J].Food Hydrocolloids,2014,40:104-114.
[9]Merce A L,Landaluze J S,Mangrich A S,et al.Complexes of arabinogalactan of Pereskia aculeata and Co2+,Cu2+,Mn2+,and Ni2+[J].Bioresource technology,2001,76(1):29-37.
[10]Sobrinho S S,Costa L L,Alves C A A G,et al.Emulsified cooked sausages enriched with flour from ora-pro-nobis leaves(Pereskia aculeata Miller)[J].2015,22(1):318.
[11]Lima Junior F A,Concei觭觔o M C,Vilela De Resende J,et al.Response surface methodology for optimization of the mucilage extraction process from Pereskia aculeata Miller[J].Food Hydrocolloids,2013,33(1):38-47.
[12]Agostini-Costa T S,Pêssoa G K A,Silva D B,et al.Carotenoid composition of berries and leaves from a Cactaceae Pereskia species[J].Journal of Functional Foods,2014,11:178-184.
[13]Souza L F,De Barros I B,Mancini E,et al.Chemical composition and biological activities of the essential oils from two Pereskia species grown in Brazil[J].Nat Prod Commun,2014,9(12):1805-1808.
[14]Pinto N D C C,Duque A P D N,Pacheco N R,et al.Pereskia aculeata:A plant food with a ntinociceptive activity[J].Pharmaceutical Biology,2015,53(12):1780-1785.
[15]Pinto N D C C,Machado D C,Da Silva J M,et al.Pereskia aculeata Miller leaves present in vivo topical antiinflammatory activity in models of acute and chronic dermatitis[J].Journal of Ethnopharmacology,2015,173:330-337.
[16]Pinto N D C C,Cassini-Vieira P,Souza-Fagundes EMD,et al.Pereskia aculeata Miller leaves accelerate excisional wound healing in mice[J].Journal of Ethnopharmacology,2016,194:131-136.
[17]Pinto N D C C,Duque A P D N,Pacheco N R,et al.Pereskia aculeata:A plant food with antinociceptive activity[J].Pharmaceutical Biology,2015,53(12):1780-1785.
[18]de Souza M D S S,Barbalho S M,Guiguer E L,et al.Effects of Pereskia aculeata Miller on the Biochemical profiles and body composition of wistar rats[J].Journal of Biosciences and Medicines,2015,03(07):82-89.
[19]Barbalho S M,Guiguer L,Marinelli P S,et al.Pereskia aculeata Miller Flour:Metabolic effects and composition[J].Journal of Medicinal Food,2016,19(9):890-894.
[20]Souza L,Caputo L,Inchausti De Barros I,et al.Pereskia aculeata Muller(Cactaceae)Leaves:chemical composition and biological activities[J].International Journal of Molecular Sciences,2016,17(9):1478.
[21]Pinto Ncc SRCM.Cytotoxic and antioxidant activity of Pereskia aculeata Miller[J].Pharmacology online,2012(3):63-69.