海南霉素预混剂对鸡柔嫩艾美耳球虫病的疗效试验
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摘要
为研究海南霉素预混剂对鸡球虫病的疗效,采用人工感染的方式进行试验,并与盐霉素、莫能菌素、尼卡巴嗪、地克珠利相关制剂进行比较。选取180只健康雏鸡随机分为9组,每组20只,除健康对照组外,每只鸡经嗉囊接种柔嫩艾美耳球虫卵囊105个。海南霉素预混剂设低、中、高3个剂量组,海南霉素的浓度分别为2.5 mg/kg、7.5 mg/kg、12.5 mg/kg。受试药物与对照药物均经混饲给药,自由采食,连用9 d。结果显示:海南霉素预混剂连用9 d,低、中、高剂量组的平均抗球虫指数分别为122.4、164.1、159.8,海南霉素预混剂高、中剂量组能显著降低发病死亡率,对鸡柔嫩艾美耳球虫病有较好的疗效。
To evaluate the curative effect of Hainanmycin premix on chicken coccidiosis, artificial infection was conducted and compared with the preparations of Salinomycin, Monensin, Nicarbazin and Diclazuril. One hundred and eighty healthy chicks were randomly divided into 9 groups, 20 birds in each. Except for the healthy control group,105 oocysts of Eimeria tenella were inoculated into the chickens via crop. The low, medium and high dose groups of Hainanmycin premix were 2.5 mg/kg, 7.5 mg/kg and 12.5 mg/kg respectively. The tested drug and comparative drugs were mixed into feed. The chickens were fed for ten days ad libitum. The results showed that ten days after a continuous use of drugs, ACI value of low, medium and high dose groups were 122.4, 164.1 and 159.8 respectively. Medium and high dose groups of Hainanmycin premix could significantly reduce the morbidity and mortality, and had a good effect against Eimeria tenella.
To evaluate the curative effect of Hainanmycin premix on chicken coccidiosis, artificial infection was conducted and compared with the preparations of Salinomycin, Monensin, Nicarbazin and Diclazuril. One hundred and eighty healthy chicks were randomly divided into 9 groups, 20 birds in each. Except for the healthy control group,105 oocysts of Eimeria tenella were inoculated into the chickens via crop. The low, medium and high dose groups of Hainanmycin premix were 2.5 mg/kg, 7.5 mg/kg and 12.5 mg/kg respectively. The tested drug and comparative drugs were mixed into feed. The chickens were fed for ten days ad libitum. The results showed that ten days after a continuous use of drugs, ACI value of low, medium and high dose groups were 122.4, 164.1 and 159.8 respectively. Medium and high dose groups of Hainanmycin premix could significantly reduce the morbidity and mortality, and had a good effect against Eimeria tenella.
引文
[1]刘高生,卢升云.鸡球虫病的防治[J].中国家禽,2004,26(11):30-32.
[2]黄兵,赵其平,韩红玉,等.海南霉素对鸡球虫病的预防和治疗效果评价[J].中国兽医杂志,2002,38(10):6-9.
[3]JOHNSON J,REID W M.Anticoccidial drugs:Lesion scoring techniques in battery and floor-pen experiments with chickens[J].Experimental Parasitology,1970,28(1):30-36.
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[7]蒋金书,林昆华.Lerbek等3种药物对鸡球虫病的抗球虫效果[J].中国兽医杂志,1992(9):41-42.
[8]角田清监修,陈宜译.鸡球虫病[M].上海:上海科技出版社,1986:90-91.
[9]郑月华,褚德明,卜仕金,等.海南霉素抗球虫效力试验[J].中国饲料,1992(5):30-31.
[10]聂奎,包尔泉,李明伟,等.鸡球素防治柔嫩艾美尔球虫的疗效试验[J].黑龙江畜牧兽医,1995(3):20-21.
[11]吴薛忠,黄兵,赵其平,等.鸡球素对五种鸡球虫的药效试验[J].中国兽医科学,1994(11):25-26.
[12]聂奎,李明伟.鸡球素对鸡球虫病治疗和预防效果观察[J].畜禽业,1994(10):17-18.
[2]黄兵,赵其平,韩红玉,等.海南霉素对鸡球虫病的预防和治疗效果评价[J].中国兽医杂志,2002,38(10):6-9.
[3]JOHNSON J,REID W M.Anticoccidial drugs:Lesion scoring techniques in battery and floor-pen experiments with chickens[J].Experimental Parasitology,1970,28(1):30-36.
[4]MSD VETERINARY.Agricultural technical service anticoccidial index-a measure of coccidiostat efficacy[M].New York:Merck Sharp&Dohme International,1976:1-4.
[5]MOREHOUSE N F,BARON R R.Coccidiosis:Evaluation of coccidiostats by mortality,weight grains,and fecal scores[J].Experimental Parasitology,1970,28(1):25-29.
[6]NORTON C C,HEIN H E.Eimeria maxima:A comparison of two laboratory strains with a fresh isolate[J].Parasitology,1976,72(3):345-354.
[7]蒋金书,林昆华.Lerbek等3种药物对鸡球虫病的抗球虫效果[J].中国兽医杂志,1992(9):41-42.
[8]角田清监修,陈宜译.鸡球虫病[M].上海:上海科技出版社,1986:90-91.
[9]郑月华,褚德明,卜仕金,等.海南霉素抗球虫效力试验[J].中国饲料,1992(5):30-31.
[10]聂奎,包尔泉,李明伟,等.鸡球素防治柔嫩艾美尔球虫的疗效试验[J].黑龙江畜牧兽医,1995(3):20-21.
[11]吴薛忠,黄兵,赵其平,等.鸡球素对五种鸡球虫的药效试验[J].中国兽医科学,1994(11):25-26.
[12]聂奎,李明伟.鸡球素对鸡球虫病治疗和预防效果观察[J].畜禽业,1994(10):17-18.