高强度聚焦超声消融治疗子宫腺肌症的临床效果
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摘要
目的探究高强度聚焦超声消融治疗子宫腺肌症的安全性及有效性。方法选取2013年1月～2017年1月在我院治疗的子宫腺肌症患者52例,随机分为治疗组、对比组,每组各26例。治疗组采用高强度聚焦超声消融治疗,对比组采用药物治疗。比较两组治疗后的临床疗效、并发症发生情况。结果治疗组的总有效率(88.46%)高于对照组(76.92%),差异有统计学意义(P<0.05)。治疗组治疗后的临床症状评分低于对照组,病灶体积及直径小于对照组,差异有统计学意义(P<0.05)。两组的不良事件总发生率比较,差异无统计学意义(P>0.05)。结论高强度聚焦超声消融治疗子宫腺肌症的效果显著,安全性较好,可改善患者的生活质量,具有临床应用价值。
Objective To investigate the safety and effectiveness of high intensity focused ultrasound ablation in the treatment of adenomyosis. Methods All of 52 patients with adenomyosis treated in our hospital from January 2013 to January 2017 were selected and they were randomly divided into the treatment group and control group, there were 26 cases in each group. The treatment group was treated with high intensity focused ultrasound ablation, while the control group was treated with drugs. The clinical efficacy and the incidence of complications after treatment between the two groups were compared. Results The total effective rate of the treatment group(88.46%) was higher than that of the control group(76.92%), and the difference was statistically significant(P<0.05). After treatment, the clinical symptom score of the treatment group was lower than that of the control group, and the volume and diameter of the lesion were smaller than those of the control group, and the differences were statistically significant(P<0.05). There was no significant difference in the total incidence of adverse events between the two groups(P>0.05). Conclusion The effect of high intensity focused ultrasound ablation in the treatment of adenomyosis is significant, it has good safety and can improve the quality of life of patients, and has clinical application value.
Objective To investigate the safety and effectiveness of high intensity focused ultrasound ablation in the treatment of adenomyosis. Methods All of 52 patients with adenomyosis treated in our hospital from January 2013 to January 2017 were selected and they were randomly divided into the treatment group and control group, there were 26 cases in each group. The treatment group was treated with high intensity focused ultrasound ablation, while the control group was treated with drugs. The clinical efficacy and the incidence of complications after treatment between the two groups were compared. Results The total effective rate of the treatment group(88.46%) was higher than that of the control group(76.92%), and the difference was statistically significant(P<0.05). After treatment, the clinical symptom score of the treatment group was lower than that of the control group, and the volume and diameter of the lesion were smaller than those of the control group, and the differences were statistically significant(P<0.05). There was no significant difference in the total incidence of adverse events between the two groups(P>0.05). Conclusion The effect of high intensity focused ultrasound ablation in the treatment of adenomyosis is significant, it has good safety and can improve the quality of life of patients, and has clinical application value.
引文
[1]朱丽华,杜学谦.高强度聚焦超声消融治疗子宫腺肌症的临床价值分析[J].医学影像学杂志,2017,27(10):2035-2038.
[2]王体勇,刘敏.高强度聚焦超声消融治疗子宫腺肌症的临床研究[J].中国保健营养,2016,26(30):14.
[3]陈敏,李铁军,陈强等.高强度聚焦超声消融子宫腺肌症的临床剂量学研究[J].重庆医学,2013,42(20):2369-2371,2375.
[4]刘君,苏园园.高强度聚焦超声消融治疗子宫腺肌症的临床研究[J].分子影像学杂志,2016,39(2):100-102.
[5]朱晓红.高强度聚焦超声消融治疗子宫腺肌症和子宫肌瘤的安全性及短期疗效观察[J].中国实用医药,2018,13(10):68-69.
[6]王丽萍,翁亚娟,王亚金,等.高强度聚焦超声在子宫腺肌症治疗中的价值[J].陕西医学杂志,2012,41(10):1318-1319.
[7]杨欣,王晓娜,胡美丽,等.保定地区高强度聚焦超声消融治疗子宫肌瘤及腺肌症的临床分析[J].重庆医学,2015,44(36):5126-5129.
[8]杨欣,王晓娜,胡美丽,等.高强度聚焦超声消融子宫腺肌症48例临床疗效观察[J].河北医科大学学报,2016,37(1):83-86.
[9]贾红知,张瑶瑶.高强度聚焦超声消融治疗子宫腺肌症的临床应用分析[J].中国实用医药,2018,13(27):62-64.
[10]刘小丽,马华.高强度聚焦超声治疗子宫腺肌症致腹壁子宫瘘临床报告[J].临床误诊误治,2016,29(8):60-62.
[11]吴莺,高悦,王燕,等.音乐治疗在高强度聚焦超声消融子宫腺肌症中的应用[J].中国医学装备,2013,10(10):83-85.
[12]陈红坚,甘娜,文勇,等.高强度聚焦超声治疗子宫肌瘤和子宫腺肌瘤的临床应用[J].临床超声医学杂志,2012,14(2):127-130.
[13]许永华.磁共振导航高强度聚焦超声的临床应用及进展[J].中国介入影像与治疗学,2011,8(4):341-343.
[14]崔杰,许永华,田绍创,等.影响聚焦超声治疗子宫腺肌病消融率的相关因素初步分析[J].中华临床医师杂志(电子版),2015,9(10):82-85.
[15]范宏杰,彭清,寸江平,等.高强度聚焦超声消融局限型子宫腺肌症[J].中国介入影像与治疗学,2018,15(9):540-543.
[2]王体勇,刘敏.高强度聚焦超声消融治疗子宫腺肌症的临床研究[J].中国保健营养,2016,26(30):14.
[3]陈敏,李铁军,陈强等.高强度聚焦超声消融子宫腺肌症的临床剂量学研究[J].重庆医学,2013,42(20):2369-2371,2375.
[4]刘君,苏园园.高强度聚焦超声消融治疗子宫腺肌症的临床研究[J].分子影像学杂志,2016,39(2):100-102.
[5]朱晓红.高强度聚焦超声消融治疗子宫腺肌症和子宫肌瘤的安全性及短期疗效观察[J].中国实用医药,2018,13(10):68-69.
[6]王丽萍,翁亚娟,王亚金,等.高强度聚焦超声在子宫腺肌症治疗中的价值[J].陕西医学杂志,2012,41(10):1318-1319.
[7]杨欣,王晓娜,胡美丽,等.保定地区高强度聚焦超声消融治疗子宫肌瘤及腺肌症的临床分析[J].重庆医学,2015,44(36):5126-5129.
[8]杨欣,王晓娜,胡美丽,等.高强度聚焦超声消融子宫腺肌症48例临床疗效观察[J].河北医科大学学报,2016,37(1):83-86.
[9]贾红知,张瑶瑶.高强度聚焦超声消融治疗子宫腺肌症的临床应用分析[J].中国实用医药,2018,13(27):62-64.
[10]刘小丽,马华.高强度聚焦超声治疗子宫腺肌症致腹壁子宫瘘临床报告[J].临床误诊误治,2016,29(8):60-62.
[11]吴莺,高悦,王燕,等.音乐治疗在高强度聚焦超声消融子宫腺肌症中的应用[J].中国医学装备,2013,10(10):83-85.
[12]陈红坚,甘娜,文勇,等.高强度聚焦超声治疗子宫肌瘤和子宫腺肌瘤的临床应用[J].临床超声医学杂志,2012,14(2):127-130.
[13]许永华.磁共振导航高强度聚焦超声的临床应用及进展[J].中国介入影像与治疗学,2011,8(4):341-343.
[14]崔杰,许永华,田绍创,等.影响聚焦超声治疗子宫腺肌病消融率的相关因素初步分析[J].中华临床医师杂志(电子版),2015,9(10):82-85.
[15]范宏杰,彭清,寸江平,等.高强度聚焦超声消融局限型子宫腺肌症[J].中国介入影像与治疗学,2018,15(9):540-543.