超分子水杨酸在医学美容中的应用与展望
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摘要
超分子水杨酸作为一种非常重要的天然活性成分,因其良好的药理活性作用,在皮肤治疗、医疗美容领域有着重大的应用价值,是临床应用较为广泛的药物之一。本文阐述了超分子水杨酸在美容、抗菌、修复、抗衰老等方面的多种功效,它具有抗炎、调理角质细胞、淡化色素沉着,抗血凝促进微循环、舒缓炎症、改善皮肤外观、增强皮肤细胞新陈代谢的作用,此外,超分子水杨酸还具有保湿、控油、清理缩小毛孔、抗敏祛屑的作用,超分子水杨酸广泛应用于治疗痤疮、炎症后色素沉着、皮肤炎症、皮肤光老化等疾病,在减少皮肤斑点、改善皮肤外观和加速皮肤新陈代谢方面都有主要作用,可以从整体上改善皮肤外观质地、减少细纹和皱纹。在治疗合适的适应证时,可以考虑较长时间的使用,超分子水杨酸的应用,极大的拓展了水杨酸的研究视野,使水杨酸在医学治疗和美容中具有更加安全、稳定、高效的作用,显示出水杨酸应用的崭新前景。
Salicylic acid, as a very important natural active ingredient, is one of the most widely used drugs in the ? eld of skin treatment and medical cosmetology due to its good pharmacological activity. This paper expounds the supramolecular salicylic acid in hairdressing, antibacterial, repair, anti-aging, etc, with a variety of efficacy, supramolecular salicylic acid has antiin? ammatory, regulate cutin cell, the desalination pigment AD cool-headed, which promote microcirculation, build the skin weak acid ring, relieve in? ammation, improve skin appearance, enhance the effect of the metabolism of skin cells, in addition,the supramolecular salicylic acid also has the moisturizing, containment, clean up shrink the pores, anti-allergic remove crumbs,supramolecular salicylic acid is widely used in treatment of acne, pigmentation after in? ammation, skin in? ammation, skin aging diseases such as light, Reduce skin spots in appearance and accelerate the metabolism of skin, improve skin has main effect, can improve skin appearance from the overall quality of a material, reduce ? ne lines and wrinkles, in the treatment of appropriate indications, can consider to use a long time, the application of supramolecular salicylic acid, greatly broadened the research ? eld of vision of salicylic acid, salicylic acid in medical treatment and beauty with a more secure, stable, ef? cient,shows a new prospect of salicylic acid application.
Salicylic acid, as a very important natural active ingredient, is one of the most widely used drugs in the ? eld of skin treatment and medical cosmetology due to its good pharmacological activity. This paper expounds the supramolecular salicylic acid in hairdressing, antibacterial, repair, anti-aging, etc, with a variety of efficacy, supramolecular salicylic acid has antiin? ammatory, regulate cutin cell, the desalination pigment AD cool-headed, which promote microcirculation, build the skin weak acid ring, relieve in? ammation, improve skin appearance, enhance the effect of the metabolism of skin cells, in addition,the supramolecular salicylic acid also has the moisturizing, containment, clean up shrink the pores, anti-allergic remove crumbs,supramolecular salicylic acid is widely used in treatment of acne, pigmentation after in? ammation, skin in? ammation, skin aging diseases such as light, Reduce skin spots in appearance and accelerate the metabolism of skin, improve skin has main effect, can improve skin appearance from the overall quality of a material, reduce ? ne lines and wrinkles, in the treatment of appropriate indications, can consider to use a long time, the application of supramolecular salicylic acid, greatly broadened the research ? eld of vision of salicylic acid, salicylic acid in medical treatment and beauty with a more secure, stable, ef? cient,shows a new prospect of salicylic acid application.
引文
[1]AL-Talib H,AL-Khateed A,Hameed A,et al.Efficacy and safety of superfi cial chemical peeling in treadment of active acne vulgaris[J].An Bras Dermatol,2007,92(2):212-216.
[2]车敦发,管海宏,曹扬.2%水杨酸凝胶治疗寻常痤疮的随机双盲对照研究[J].中国美容医学,2006,15(5):561-563.
[3]OConnor AA,Lowe PM,Shumack S,et al.Chemical peels:A review of current practice[J].Australas J Dermatol,2018,59(3):171-181.
[4]Cunliffe WJ,Gollnick HPM.Acne diagnosis and management[M].Martin Dunitz Ltd,2001:107-114.
[5]Grimes PE.The safety and effi cacy of salicylic acid chemical peels in darker racial-ethnic groups[J].Derm Surg,1999,25(1):18-22.
[6]Kligman D,Kligman AM.Salicylic acid as a peeling agent for the treatment of acne[J].Cosm Derm,1997,5:44-47.
[7]Ahn HH,Kim IH.Whitening effectc of salicylic acid peel in Asian patients[J].Dermatol Surg,2006,32(3):372-375.
[8]AbdelMeguid AM,ElazizAhmedAttallah DA,Omar H.Trichloroacetic acid versus salicylic acid in the treatment of acne vulgaris in darkskinned patients[J].Dermatol Surg,2015,41(12):1398-1404.
[9]Seite S,Rougier A,Talarico S.Randomized study comparing the efficacy and tolerance of a lipohydroxy acid shampoo to a ciclopiroxolamine shampoo in the treatment of scalp seborrheic dermatitis[J].J Cosmet Dermatol,2009,8(4):249-253.
[10]Lee HS,Kim IH.Salicylic acid peels for the treatment of acne vulgaris in Asian patients[J].Dermatol Surg,2003,29(12):1196-1199.
[11]Kligman D,Kligman AM.Salicylic acid peels for the treatment of photoaging[J].Dermatol Surg,1998,24(3):325-328.
[12]Imayama S,Ueda S,Isoda M.Histologic changes in the skin of hairless mice following peeling with salicylic acid[J].Arch Dermatol,2000,136(11):1390-1395.
[13]Baran R,Maibach H.Textbook of Cosmetic Dermatology[M].2nd edit.Martin Dunitz,1998:436.
[2]车敦发,管海宏,曹扬.2%水杨酸凝胶治疗寻常痤疮的随机双盲对照研究[J].中国美容医学,2006,15(5):561-563.
[3]OConnor AA,Lowe PM,Shumack S,et al.Chemical peels:A review of current practice[J].Australas J Dermatol,2018,59(3):171-181.
[4]Cunliffe WJ,Gollnick HPM.Acne diagnosis and management[M].Martin Dunitz Ltd,2001:107-114.
[5]Grimes PE.The safety and effi cacy of salicylic acid chemical peels in darker racial-ethnic groups[J].Derm Surg,1999,25(1):18-22.
[6]Kligman D,Kligman AM.Salicylic acid as a peeling agent for the treatment of acne[J].Cosm Derm,1997,5:44-47.
[7]Ahn HH,Kim IH.Whitening effectc of salicylic acid peel in Asian patients[J].Dermatol Surg,2006,32(3):372-375.
[8]AbdelMeguid AM,ElazizAhmedAttallah DA,Omar H.Trichloroacetic acid versus salicylic acid in the treatment of acne vulgaris in darkskinned patients[J].Dermatol Surg,2015,41(12):1398-1404.
[9]Seite S,Rougier A,Talarico S.Randomized study comparing the efficacy and tolerance of a lipohydroxy acid shampoo to a ciclopiroxolamine shampoo in the treatment of scalp seborrheic dermatitis[J].J Cosmet Dermatol,2009,8(4):249-253.
[10]Lee HS,Kim IH.Salicylic acid peels for the treatment of acne vulgaris in Asian patients[J].Dermatol Surg,2003,29(12):1196-1199.
[11]Kligman D,Kligman AM.Salicylic acid peels for the treatment of photoaging[J].Dermatol Surg,1998,24(3):325-328.
[12]Imayama S,Ueda S,Isoda M.Histologic changes in the skin of hairless mice following peeling with salicylic acid[J].Arch Dermatol,2000,136(11):1390-1395.
[13]Baran R,Maibach H.Textbook of Cosmetic Dermatology[M].2nd edit.Martin Dunitz,1998:436.