选择性断流术对门静脉高压症治疗作用的临床研究
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摘要
目的:研究选择性断流术对门静脉高压症治疗效果。方法:2012年3月~2016年7月间门静脉高压行选择性断流术治疗的38例为研究组,同时与此前接受联合断流术治疗的40例(对照组)治疗结果比较。结果:术后两组比较,研究组门静脉压力明显的低于对照组,差异具有统计学意义(P<0.05);研究组术后门静脉血栓、门静脉高压性胃病及食道曲张静脉再发明显的低于对照组,差异具有统计学意义(P<0.05);研究组术后好转率明显高于对照组,差异具有统计学意义(P<0.05)。结论:选择性断流术应用于门静脉高压症疗效显著,有效缓解门静脉压力,明显的降低食道曲张静脉再发、门静脉高压性胃病及门静脉血栓等并发症的发生,有利于患者术后康复,值得推广。
Objective: To study the effect of selective discontinuation on the treatment of portal hypertension. Methods:between March 2012 to July 2012 for the treatment of portal hypertension line selective depletion of 38 cases for the team, at the same time and the previous combination for the treatment of block of 40 cases(control group) compared treatment results.Results: compared with the two groups, the pressure of the portal vein was significantly lower than that in the control group,and the difference was statistically significant(P<0.05). In the study group, the postoperative portal vein thrombosis, portal hypertension and esophageal varicose veins were significantly lower than the control group, and the difference was statistically significant(P<0.05). The postoperative rate of the study group was significantly higher than the control group, and the difference was statistically significant(P<0.05). Conclusion: selective cut-out used in portal hypertension curative effect is distinct, effectively alleviate the pressure of the portal vein, significantly lower esophageal varicose vein recurrence, portal hypertension gastropathy and portal vein thrombosis complications, is beneficial to patients with postoperative rehabilitation, is worth promoting.
Objective: To study the effect of selective discontinuation on the treatment of portal hypertension. Methods:between March 2012 to July 2012 for the treatment of portal hypertension line selective depletion of 38 cases for the team, at the same time and the previous combination for the treatment of block of 40 cases(control group) compared treatment results.Results: compared with the two groups, the pressure of the portal vein was significantly lower than that in the control group,and the difference was statistically significant(P<0.05). In the study group, the postoperative portal vein thrombosis, portal hypertension and esophageal varicose veins were significantly lower than the control group, and the difference was statistically significant(P<0.05). The postoperative rate of the study group was significantly higher than the control group, and the difference was statistically significant(P<0.05). Conclusion: selective cut-out used in portal hypertension curative effect is distinct, effectively alleviate the pressure of the portal vein, significantly lower esophageal varicose vein recurrence, portal hypertension gastropathy and portal vein thrombosis complications, is beneficial to patients with postoperative rehabilitation, is worth promoting.
引文
[1]卢翔,赵青川,韩国宏,等.肝硬化门静脉高压症术后门静脉血栓形成危险因素研究[J].中国实用外科杂志,2013,33(03):205-207.
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[3]赵亮,谭贵芳.脾切断流术对肝硬化门静脉高压患者血清HGF、TGF-β1和肝功能的影响[J].中国老年学杂志,2015,35(13):3677-3678.
[4]贺加星,阴继凯,刘凡,等.肝硬化门静脉高压并发上消化道出血的相关危险因素分析[J].中国普通外科杂志,2015,24(01):127-130.
[5]李宏为,陈皓.当代门静脉高压症治疗方法合理选择[J].中国实用外科杂志,2014,34(01):24-27.
[6]陈小刚,张培瑞,李志伟,等.肝硬化门静脉高压脾切断流术后影响门静脉系统血栓形成的因素[J].中国普通外科杂志,2013,22(01):67-70.
[7]李小珍,罗地来,朱程,等.保留脾脏的选择性断流联合脾肾静脉桥式分流术对肝硬化合并门静脉高压患者免疫功能的影响[J].重庆医学,2013,42(01):24-26+30.
[8]颜碧莲,马倩红,梁言珍,等.FTS理念用于肝硬化门脉高压症门静脉断流术围术期的临床价值[J].黑龙江医药,2017,30(04):746-749.
[2]孙孝东,栗素文,田洪伟.保脾断流术治疗老年肝硬化门静脉高压患者的疗效[J].中国老年学杂志,2017,37(09):2225-2227.
[3]赵亮,谭贵芳.脾切断流术对肝硬化门静脉高压患者血清HGF、TGF-β1和肝功能的影响[J].中国老年学杂志,2015,35(13):3677-3678.
[4]贺加星,阴继凯,刘凡,等.肝硬化门静脉高压并发上消化道出血的相关危险因素分析[J].中国普通外科杂志,2015,24(01):127-130.
[5]李宏为,陈皓.当代门静脉高压症治疗方法合理选择[J].中国实用外科杂志,2014,34(01):24-27.
[6]陈小刚,张培瑞,李志伟,等.肝硬化门静脉高压脾切断流术后影响门静脉系统血栓形成的因素[J].中国普通外科杂志,2013,22(01):67-70.
[7]李小珍,罗地来,朱程,等.保留脾脏的选择性断流联合脾肾静脉桥式分流术对肝硬化合并门静脉高压患者免疫功能的影响[J].重庆医学,2013,42(01):24-26+30.
[8]颜碧莲,马倩红,梁言珍,等.FTS理念用于肝硬化门脉高压症门静脉断流术围术期的临床价值[J].黑龙江医药,2017,30(04):746-749.